Anticoagulation in the ICU: Contact Pathway Inhibition Future

Anticoagulation in the ICU: Contact Pathway Inhibition Future

Bleeding and thrombotic complications are the main cause of morbidity and mortality in critically ill patients on the intensive care unit (ICU), receiving short-term percutaneous mechanical circulatory support (pMCS) by extracorporeal... read more

COVID-19 Critical and Intensive Care Medicine Essentials

COVID-19 Critical and Intensive Care Medicine Essentials

This book provides healthcare professionals in Critical Care setting an easy consultation guide to fight against COVID-19. The book is divided into sections: Fundamentals of COVID-19, Pneumological critical care, Neurological... read more

Traumatic Hemorrhage and Chain of Survival

Traumatic Hemorrhage and Chain of Survival

Trauma is the number one cause of death among Americans between the ages of 1 and 46 years, costing more than $670 billion a year. Following death related to central nervous system injury, hemorrhage accounts for the majority... read more

Leriche Syndrome Diagnosed Due to Polytrauma

Leriche Syndrome Diagnosed Due to Polytrauma

In this case, conservative therapy was initially chosen for Leriche syndrome. However, the complex factors in the acute phase of trauma led to development of hemorrhagic necrosis, requiring amputation of the lower extremity.... read more

Neutrophilic Inflammation, Immunothrombosis May Distinguish Severe COVID-19 From Influenza

Neutrophilic Inflammation, Immunothrombosis May Distinguish Severe COVID-19 From Influenza

Severe coronavirus disease 2019 (COVID-19) is associated with immunothrombotic, neutrophil-containing vessel occlusions in the lung, with neutrophils representing the primary immune cell component associated with clinical... read more

Clinical and Pathophysiologic Aspects of ECMO-associated Hemorrhagic Complications

Clinical and Pathophysiologic Aspects of ECMO-associated Hemorrhagic Complications

Extracorporeal membrane oxygenation (ECMO) is increasingly used to treat severe cases of acute respiratory or cardiac failure. Hemorrhagic complications represent one of the most common complications during ECMO, and can... read more

Abnormalities in the Host Immune Response During Hospitalization for Sepsis

Abnormalities in the Host Immune Response During Hospitalization for Sepsis

In this cohort study of 483 patients who survived hospitalization with sepsis at 12 US hospitals, 25.8% had elevated high-sensitivity C-reactive protein levels (a marker of inflammation) at 3 months, 30.2% at 6 months, and... read more

Haemostatic Resuscitation in Trauma: The Next Generation

Haemostatic Resuscitation in Trauma: The Next Generation

The next generation of haemostatic resuscitation aims at applying a ratio 1:1:1 driven strategy while using antifibrinolytics, haemostatic monitoring and avoiding critical fibrinogen deficiency by substitution. Mortality... read more

Sepsis Prediction in Critically Ill Patients by Platelet Activation Markers on ICU Admission

Sepsis Prediction in Critically Ill Patients by Platelet Activation Markers on ICU Admission

Platelets have been involved in both immune surveillance and host defense against severe infection. To date, whether platelet phenotype or other hemostasis components could be associated with predisposition to sepsis in critical... read more