Presenting the most up-to-date techniques for the detection, genotyping, and investigation of methicillin-resistant S. aureus (MRSA), this second edition of Methicillin-Resistant Staphylococcus aureus... read more

A superbug resistant to all known antibiotics that can cause “severe” infections or even death is spreading undetected through hospital wards across the world, scientists in Australia warned... read more

Current standard laboratory methods for detection of oxacillin resistance require for isolation, identification, and susceptibility testing at least 48–72 h, although the multiplex PCR assay used is... read more

From 2008 to 2015, total acute care utilization for the treatment of low-acuity conditions and associated spending per member in the United States increased, and utilization of non-ED acute care venues... read more

Only few new molecules have an adequate activity against MDR gram-negative pathogens, especially carbapenemase-producer strains. Among these, ceftozolane/tazobactam has been recently approved for clinical... read more

The struggle to perform well is universal: each of us faces fatigue, limited resources, and imperfect abilities in whatever we do. But nowhere is this drive to do better more important than in medicine,... read more

Standard treatment of critically ill patients undergoing mechanical ventilation is continuous sedation. Daily interruption of sedation has a beneficial effect, and in the general ICU of Odense University... read more

Care that is inadequately respectful to patients and families in the setting of critical illness is prevalent but does not appear to be associated with clinical characteristics. The incidence of such emotional... read more

The team of nurses that Tilda Shalof found herself working with in the intensive care unit (ICU) of a big-city hospital was known as “Laura’s Line.” They were a bit wild: smart, funny,... read more

These results confirm previous observational reports that the presence of an endotracheal tube (ETT) remains a major obstacle to the provision of rehabilitation for critically ill patients. Despite rehabilitation... read more

Patients rely on doctors to look after their mental health but is enough being done to help the doctors when they are the ones with problems? There are concerns that some medical professionals in England... read more

How do we choose what we wear when seeing patients? Is it by what tradition dictates? Do we need to meet our institution’s dress code? Or do we just like what makes us comfortable? (Those scrubs... read more

While representing the cutting edge of civilization everywhere, mothers and their newborn infants are a population particularly vulnerable to sepsis.1 By recognizing the importance of antiseptic prophylaxis... read more

A New York State requirement that all hospitals report compliance with protocols to treat severe sepsis and septic shock appears to improve care and reduce mortality from one of the most common causes... read more

Hypoxemia should certainly be avoided, but the fact that the liberal administration of oxygen to patients in intensive care units and emergency rooms tends to increase morbidity and mortality implies the... read more

In critically ill patients, it is frequently challenging to identify who will benefit from admission to the intensive care unit and life-sustaining interventions when the chances of a meaningful outcome... read more

The failure of systemic drug treatments to address numerous neurological disorders has spurred the development of alternative approaches that attempt localized treatment. These localized treatments focus... read more

Margaret Parker, MD, MCCM, speaks with Stefanie G. Ames, MD, about the article “Hospital Variation in Risk-Adjusted Pediatric Sepsis Mortality,” published in the May 2018 issue of Pediatric... read more

Shortages of commonplace generic drugs have plagued hospitals in recent years. And with short supplies and fewer suppliers for key drugs, there have been price increases. Hospital purchasing agents keep... read more

This mixed methods study identified that families of trauma patients have different needs to families of general patients and the nurses rated the needs of the families of trauma patients as less important... read more

Advocates of mandated staffing ratios say they improve patient outcomes. A recent study finds otherwise. Nurse-to-patient ratios are a hot button issue. Look no further than Massachusetts for an example.... read more

A research expedition to Mount Everest has shed light on the unique physiological basis of adaptations seen in the native Sherpa people, which make them better suited to life at high altitude. This improved... read more

One in seven NHS hospital operations are being cancelled just before they are due to take place, often because of a lack of beds, staff or operating theatres, research reveals. Of 26,171 procedures due... read more

With the integration of bedside echocardiography into cardiac arrest, we now have a real-time tool to help us glean some of this critical missing information, as well as offer procedural guidance and prognostic... read more