Surgery guidance updated for hospitals struggling with capacity constraints
Four healthcare groups again updated their guidance for hospitals to maintain essential surgeries during the COVID-19 pandemic. The American Hospital Association, American College of Surgeons, American Society of Anesthesiologists... read more
The Impacts of Gender Disparity in Residency Matching
A critical turning point for the female physician is highlighted in the study by Lorello et al1 as another one of the numerous inequities throughout the female physician’s career life cycle. Their study’s extensive assessment... read more
Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients
Despite recent advances in the timely restoration of impairments in the oxygen supply chain to the tissue (Yealy et al. 2014; Peake et al. 2014; Mouncey et al. 2015), circulatory shock remains a major contributor to mortality... read more
Management of Children With Fever at Risk for Pediatric Sepsis
Many febrile children (41%) present with warning signs for sepsis, with only few of them undergoing investigations or treatment for true sepsis. Children with positive isolates in blood or CSF culture presented in a heterogeneous... read more
Epidemiology of Invasive Pulmonary Aspergillosis Among COVID-19 Intubated Patients
We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence seems to change the natural history of disease. A total of 108 patients were enrolled. Prospective, multicentre study... read more
Clinical Evaluation of a High-fidelity Upper Arm Cuff to Measure Arterial Blood Pressure during Noncardiac Surgery
The new high-fidelity upper arm cuff method met the current international standards in terms of accuracy and precision. It was also very accurate to track changes in blood pressure and reliably detect severe hypotension during... read more
Prior Routine Use of NSAIDs and Important Outcomes in Hospitalised COVID-19 Patients
Coronavirus disease 2019 (COVID-19) infection causes acute lung injury, resulting from aggressive inflammation initiated by viral replication. There has been much speculation about the potential role of non-steroidal inflammatory... read more
Increased Dead Space Ventilation and Refractory Hypercapnia in Patients with COVID-19
We speculate that thromboinflammation with pulmonary microvasculature occlusion leads to a sudden increase in dead space and shunt resulting in severe hypercapnia and hypoxemia in coronavirus disease 2019 patients. Early... read more
Utility of RV Remodeling Over Risk Stratification in COVID-19
This study contributes to the growing body of literature illustrating the adverse prognostic implications of RV dilation and dysfunction in the setting of severe COVID-19. Mechanistic explanations for RV failure in this population... read more
Will COVID-19 Vaccines Save Lives? Current Trials Aren’t Designed To Tell Us
The world has bet the farm on vaccines as the solution to the pandemic, but the trials are not focused on answering the questions many might assume they are. As phase III trials of covid-19 vaccines reach their target... read more
Resilience in a Prehospital Setting – A New Focus for Future Research?
Empirical research is of crucial importance to understand, build and support resilient systems and processes, including exploring and developing interventions to improve capacity for adaptive change in a prehospital setting. Handling... read more
Evidence-Based Practice of Critical Care
Objective data and expert guidance on managing critically ill patients in unique question-based chapters that focus on best practices. Now thoroughly updated by Drs. Clifford S. Deutschman, Patrick J. Neligan, and nearly... read more
Effect of Tocilizumab vs. Standard Care on Clinical Worsening in Patients Hospitalized With COVID-19 Pneumonia
The administration of tocilizumab in patients with COVID-19 pneumonia and a Pao2/Fio2 ratio between 200 and 300 mm Hg did not reduce the risk of clinical worsening. Further blinded, placebo-controlled randomized clinical... read more
The Use of Venous Doppler to Predict Adverse Kidney Events in a General ICU Cohort
This study indicates that portal and hepatic flows may be clinical useful tools to help identify patients at risk for renal injury. It is likely that they are indicative of elevated right atrial pressure causing venous congestion,... read more
Critical Care Beds Are No Use Without Enough Specialist Staff
In 2020 there have been announcements of the expansion of critical care capacity across the NHS, while at the same time headlines have detailed stories of hospitals running out of critical care beds. And this week dire warnings... read more
Lung Histopathology in COVID-19 as Compared to SARS and H1N1 Influenza
Diffuse alveolar damage (DAD) was reported in 88% of patients with COVID-19. This is similar to both H1N1 (90%) and SARS (98%). Pulmonary microthrombi was reported in 57% of patients with COVID-19. This was similar to... read more
Panel Provides a Look at the Fast-changing Science of COVID-19 Diagnosis, Therapy, and Prevention
As the pace of research related to COVID-19 continues at an unprecedented rate, clinicians on the front line of the pandemic are challenged to keep up with a deluge of information to ensure they are bringing best practices... read more
Implantation of Impella CP Left Ventricular Assist Device Under the Guidance of 3D Intracardiac Echocardiography
Three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP for left ventricular mechanical support and should be carefully considered in cases where other imaging modalities... read more
Cancer Biomarker Measurement using a Smartphone
Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more
Some Signs of Recovery From Severe COVID-19 Lung Damage
In two early studies, researchers said some patients showed signs of healing just weeks after leaving the hospital. Lingering shortness of breath and diminished stamina have dogged many COVID patients whose lungs were... read more
Outcomes of Patients Requiring Prolonged Acute vs. Short-Term Mechanical Ventilation
Over one-third of all hospitalized patients on mechanical ventilation require it for greater than or equal to 4 days. Prolonged acute mechanical ventilation patients exhibit a higher burden of both chronic and acute illness... read more
Dr. Fauci Headlines COVID-19-focused Opening Session at CHEST 2020
The COVID-19 pandemic upended the practices and lives of CHEST members—and changed CHEST 2020 into a virtual meeting—so it's fitting that this year's Opening Session focused on the defining global event of the year. Anthony... read more
