Managing Recurrent Septic Shock – Dual Blood Purification with CytoSorb and oXiris

This case report presents a patient with recurrent septic shock who experienced significant clinical improvement after receiving adjunctive treatment with a combination of continuous renal replacement therapy (CRRT) using... read more

Cellular Therapy with Mesenchymal Stromal Cells in Sepsis

Cellular therapy with mesenchymal stromal cells (MSCs) is a promising therapeutic modality in sepsis. Positive effects are mainly associated with frequent infusions and the dose of 1 × 106 cell/kg. Larger scale studies... read more

Association Between Early Ondansetron Use and Sepsis Risk in ICU Patients

In both patients with SOFA 3, early ondansetron use was correlated with a reduced risk of sepsis. Patients with early ondansetron use had lower odds of experiencing sepsis than patients without early ondansetron use, which... read more

Handbook of Sepsis

This recently released practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the ICU. Readers will find information on... read more

Handbook of Sepsis

Code Sepsis – Early Decompensation and Predictors

Early recognition and management of sepsis within the first hour of a sepsis alert is critical for patient survival, requiring healthcare providers to be trained to identify "red flag" symptoms like rapid breathing (tachypnea)... read more

Predicting Sepsis Outcomes – Efficacy of Early Warning Scores

In resource-limited settings, NEWS proved to be the most effective tool for early risk stratification in sepsis patients. Its adoption could significantly enhance sepsis management and improve outcomes in emergency departments... read more

Rhabdomyolysis Due to Nutritional Supplements Intake

habdomyolysis is a condition characterized by the destruction of muscle cells and subsequent release of it's intracellular contents. It is typically asymptomatic, with moderate creatine kinase elevation. Severe cases... read more

Single Lumen vs. Double Lumen Endotracheal Tube For Postoperative Swallowing Function in Lung Transplantation Patients

BackgroundThis study was conducted to investigate the effect of endotracheal tube type on post operative dysphagia in patients undergoing lung transplant surgery. Will patients who are intubated with a single lumen endotracheal... read more

Handbook of Evidence-Based Critical Care

This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding... read more

Handbook of Evidence-Based Critical Care

Prognostic Value of Composite Inflammatory Markers in COPD Patients

Elevated systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), pan-immune inflammation value (PIV), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) are associated... read more

Approach to Peripheral Neuropathy

Peripheral neuropathy is frequently encountered in the clinical setting by doctors of various specialties. Neuropathies can be approached based on the temporal profile, spatial pattern and pathology. There is a need for... read more

Using Critical Ultrasound To Predict Early Diagnosis of ICU-acquired Weakness in Septic Patients

This study uncovered pivotal indicators for predicting the occurrence of ICUAW in septic patients. Despite no significant difference in age, gender, BMI, BSA, or SOFA scores between the two groups, the significant differences... read more

The Point of Care Ultrasound Handbook

This NEW book is meant to be a reference for both the new and experienced point of care sonographer; to be a pocket guide to carry with you during your shift. We have included our best tips, tricks and any additional... read more

The Point of Care Ultrasound Handbook

Prolonged vs. Intermittent Infusion of Meropenem For Patients with Severe Infection

Prolonged infusion of meropenem is more effective than intermittent infusion in reducing mortality, improving clinical outcomes, and enhancing microbial eradication, without increasing adverse events. These benefits are... read more

Zosyn vs. Efepime: Which One Is Safer?

While both piperacillin-tazobactam and cefepime are commonly used to treat infections caused by Pseudomonas aeruginosa in hospitalized patients, there is a concern that piperacillin-tazobactam may lead to acute kidney injury... read more

Handbook of Critical Care Medicine

The management of critically ill patients is an important and integral part of internal medicine practice. Often, junior doctors and medical students receive insufficient training in this area of medicine. There are important... read more

Handbook of Critical Care Medicine

Pleural Drainage, Clinical Characteristics, and Management Strategies in the Perioperative Fontan Patient

Prolonged pleural drainage and chylothorax are common in postoperative Fontan patients and are associated with increased morbidity and mortality. Multiple medical and interventional treatment strategies exist and vary between... read more

Expert Consensus Statements on Lipids in Parenteral Nutrition

Lipids are integral to parenteral nutrition (PN) in all settings where PN is required, serving as a source of energy and essential fatty acids. In addition, lipids modulate a variety of biological functions, including inflammatory... read more

Workbook on Hemodynamic Management

This workbook focuses on hemodynamics management. Hemodynamic management should be aimed at minimizing the ischemic injury. Cerebral ischemia impairs the brain's ability to autoregulate its circulation through vasoconstriction... read more

Workbook on Hemodynamic Management