One Doctor’s Life on the Coronavirus Front Lines
Driving one evening in Wuhan, China, last month, Zhang Xiaochun pulled her car to the side of the road. She was on the verge of a breakdown. She'd been working nonstop for days at the center of China's coronavirus outbreak,... read more
Effect of Vitamin C and Thiamine on Time Alive and Free of Vasopressor Support Among Patients With Septic Shock
A 2020 randomized trial reported no difference in duration of time alive and free of vasopressor administration at 7 days among intensive care unit (ICU) patients with septic shock assigned to vitamin C, thiamine, and hydrocortisone... read more
COVID-19 Situation in Japan
Dr Adrian Wong speaks to Prof Satoru Hashimoto on the #COVID19 situation in Japan in this ESICM podcast. Dr Adrian Wong is a consultant in critical care in King’s College Hospital, London. He is the chair of the Editorial... read more
Relative Hypoglycemia in Diabetic Patients With Critical Illness
In ICU patients with diabetes, relative hypoglycemia is common, increases with higher hemoglobin A1C levels, and is a modifiable risk factor for both mortality and subsequent absolute hypoglycemia. These findings provide... read more
Validation of Neuromuscular Blocking Agent Use in ARDS
The use of Neuromuscular Blocking Agents (NMBA) could significantly decrease mortality in moderate-to-severe acute respiratory distress syndrome (ARDS) patients and decrease the incidence of barotrauma during mechanical ventilation.... read more
ECMO Support in Coronavirus Disease 2019 (COVID-19)
Extracorporeal membrane oxygenation (ECMO) use has been increasing in severe respiratory and/or cardiac failure despite implementation of conventional care. This technology has been proven valuable in treating viral pneumonia... read more
Multi-Modal Characterization of the Coagulopathy Associated With ECMO
The extracorporeal membrane oxygenation(ECMO)-associated coagulopathy is a multifactorial and quickly developing syndrome. It is characterized by individual changes of coagulation parameters and platelets and is aggravated... read more
Life Following Pediatric Septic Shock
Margaret M. Parker, MD, MCCM, and Jerry J. Zimmerman, MD, PhD, FCCM, talk about the trajectory of long-term mortality and significant health-related quality of life disability among children encountering septic shock. This... read more
Echocardiography in Pediatric and Congenital Heart Disease
This comprehensive textbook on the echocardiographic assessment of pediatric and congenital heart disease has been updated for a second edition with an emphasis on new technologies. This highly-illustrated full-color reference... read more
Review of the Current Evidence on COVID-19 in Intensive Care
Join Dr. David Lyness as he discusses the current evidence on COVID-19 in Intensive Care. A coronavirus is one of many viruses that cause diseases in mammals and birds. In humans, coronaviruses cause respiratory tract... read more
Association of Initiation of Dialysis with Hospital Length of Stay and Intensity of Care in Older Adults With Kidney Failure
In this cohort study, compared with non-dialysis care, patients who received maintenance dialysis spent more time in the hospital and were more likely to be admitted to intensive care units. This finding suggests trade-offs... read more
Critical Care Crisis and Some Recommendations During the COVID-19 Epidemic in China
The COVID-19 epidemic has placed a huge burden on the Chinese health care system. This crisis has dramatically affected the delivery of critical care due to a lack of resources, lack of prediction models and of course the... read more
Imaging Changes of Severe COVID-19 Pneumonia in Advanced Stage
The imaging changes of acute stage from a case of 75-year-old male patient with severe COVID-19 pneumonia combined acute respiratory distress syndrome (ARDS), septic shock, and multiple organ dysfunction syndrome (MODS) who... read more
The Dyspnoea-inactivity Vicious Circle in COPD: Development and External Validation of a Conceptual Model
The vicious circle of dyspnoea-inactivity has been proposed, but never validated empirically, to explain the clinical course of chronic obstructive pulmonary disease (COPD). We aimed to develop and validate externally... read more
Harmful Effects of Mechanical Ventilation on Neurocognitive Functions
Whether mechanical ventilation (MV) induces neurotoxicity that can trigger or accelerate chronic cognitive disorders is controversial. The relationship between MV and neurocognitive impairment, that persisted at hospital... read more
New Study on Prehospital Airway Control Trial Underway
Emory University Department of Emergency Medicine and Grady Memorial Hospital will take part in a U.S. Department of Defense-funded clinical trial to compare different ways to help people with traumatic injuries breathe. The... read more
How to Save Lives in a COVID-19 Pandemic
The pace of COVID-19, the ongoing novel coronavirus outbreak, has been astonishing, and it is inevitable that this will become a pandemic, if it hasn't already. When a disease is a pandemic, it considered to be an ongoing... read more
Clinical Characteristics of Coronavirus Disease 2019 in China
During the first 2 months of the current outbreak, Covid-19 spread rapidly throughout China and caused varying degrees of illness. Patients often presented without fever, and many did not have abnormal radiologic findings. The... read more
The Wuhan Coronavirus Survival Manual: How to Prepare for Pandemics and Quarantines
Panic over the coronavirus that originated in Wuhan, China is becoming more widespread and people are frantically getting prepared for the possibility of a deadly pandemic that could span the globe. Things like N95 masks... read more
Sudden Abdominal Pain with a Palpable Mass
Rectus sheath hematoma (RSH) is a rare cause of abdominal pain that is often overlooked when patients present for evaluation. The disease can mimic almost any other type of abdominal pathology, and thus the diagnosis is frequently... read more
Alton’s Antibiotics and Infectious Disease: The Layman’s Guide to Available Antibacterials in Austere Settings
Alton's Antibiotics and Infectious Disease is a unique simplified guide to using antibacterial and antifungal veterinary medications. It is meant to help the non-medical professional in disaster, survival, and other austere... read more
Association Between Hypothermia/Ischemia Ratio and Functional Outcome From Out-of-Hospital Cardiac Arrest
Although a larger hypothermia/ischemia ratio was associated with good functional outcome after out-of-hospital cardiac arrest in this cohort, this association is primarily driven by duration of time to return of spontaneous... read more
