CDC Urges Early Recognition, Prompt Treatment of Sepsis
The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more
Causes for Pauses During Simulated Pediatric Cardiac Arrest
Pauses in cardiopulmonary resuscitation occurred frequently during simulated pediatric cardiac arrest, with variable duration and underlying causes. A large percentage of pauses were greater than 10 seconds and occurred more... read more
Cochrane Strategy to 2020
Strategy to 2020 aims to put Cochrane evidence at the heart of health decision-making all over the world. It defines how we intend to accomplish this and provides a framework for Cochrane's future decision-making, helping... read more
Emergency Preparedness in Healthcare
Ludwig Lin, MD, speaks with Grete Porteous, MD, about emergency preparedness in healthcare and the role of critical care personnel in catastrophic situations. Dr. Porteous advises on how to prepare institutions for disaster... read more
Ultrasound-guided Central Venous Catheter Placement
Ultrasound-guided central venous catheter placement: a structured review and recommendations for clinical practice. Although placement of a central venous catheter (CVC) is a routine procedure in intensive care medicine and... read more
A multifaceted intervention to improve treatment with oral anticoagulants in atrial fibrillation
Oral anticoagulation is underused in patients with atrial fibrillation. We assessed the impact of a multifaceted educational intervention, versus usual care, on oral anticoagulant use in patients with atrial fibrillation.... read more
FDA Approves ‘living drug’ to Cure Cancer
FDA has approved the first treatment to redesign immune system so it attacks the cancer cells. Kymriah therapy, which leaves 83% of people free of a type of blood cancer, costs about $475,000 and was developed by Novartis.... read more
Individualizing Thresholds of Cerebral Perfusion Pressure Using Estimated Limits of Autoregulation
Individualized autoregulation-guided cerebral perfusion pressure management may be a plausible alternative to fixed cerebral perfusion pressure threshold management in severe traumatic brain injury patients. Prospective randomized... read more
Oxygen Therapy in Suspected Acute Myocardial Infarction
Routine use of supplemental oxygen in patients with suspected myocardial infarction who did not have hypoxemia was not found to reduce 1-year all-cause mortality. A total of 6629 patients were enrolled. The median duration... read more
Current Clinical Nutrition Practices in Critically Ill Patients in Latin America
In the ICU setting in Latin America, malnutrition was highly prevalent and caloric intake failed to meet targeted energy delivery in 40% of critically ill adults receiving nutrition therapy. Supplemental administration of... read more
Are contact isolation precautions (CP) necessary when caring for patients infected or colonized with endemic MRSA or VRE?
Researchers from the University of Nebraska Medical Center Division of Infectious Diseases and Nebraska Medicine Department of Infection Control and Epidemiology recently published results from a two-year observational study... read more
Hyperfibrinolysis in Severe Isolated TBI May Occur Without Tissue Hypoperfusion
Hyperfibrinolysis is associated with tissue injury in both patients with traumatic brain injury (TBI) and in non-TBI patients. However, tissue hypoperfusion is associated with hyperfibrinolysis in non-TBI patients, but not... read more
Microcirculatory assessment of patients under VA-ECMO
Of the 24 patients included in the study population, 15 survived and 9 died while on VA-ECMO. PVD of the sublingual microcirculation at initiation of VA-ECMO can be used to predict ICU mortality in patients with cardiogenic... read more
Acetaminophen in the ICU: Mixed Findings
Does having a fever help fight infection? Patients who got acetaminophen to relieve fever while in intensive care units did about as well as patients who got a placebo when it came to mortality. But in a puzzling finding,... read more
Most pediatric ICU physicians don’t use current guidelines to diagnose acute kidney injury
A study by University at Buffalo researchers has shown that physicians in pediatric intensive care units are not using the newest guidelines to diagnose acute kidney injury (AKI) in critically ill children, a practice that... read more
Septic shock with no diagnosis at 24 hours: a pragmatic multicenter prospective cohort study
The lack of a patent source of infection after 24 hours of management of shock considered septic is a common and disturbing scenario. A multicenter observational cohort study in ten intensive care units (ICU) in France.... read more
Performance of a Modern Glucose Meter in ICU
Performance of a Modern Glucose Meter in ICU and General Hospital Inpatients: 3 Years of Real-World Paired Meter and Central Laboratory Results. Due to accuracy concerns, the Food and Drug Administration issued guidance to... read more