VA-ECMO in High-Risk Pulmonary Embolism

VA-ECMO in High-Risk Pulmonary Embolism

High-risk Pulmonary Embolism (PE) has an ominous prognosis and requires emergent reperfusion therapy, primarily systemic thrombolysis (ST). In deteriorating patients or with contraindications to ST, Veno-Arterial Extracorporeal... read more

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Multiple Electrolytes Solution vs. Saline as Bolus Fluid for Pediatric Septic Shock Resuscitation

Among children presenting with septic shock, fluid resuscitation with MES (balanced crystalloid) as compared with 0.9% saline resulted in a significantly lower incidence of new and/or progressive AKI during the first 7 days... read more

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification

Ground-breaking New AI Technology for Severe Sepsis Rapid Identification

ASEP Medical Holdings Inc. announced the ground-breaking use of artificial intelligence (AI) to rapidly identify infections at increased risk of severe sepsis. The method was developed by the Hancock Lab, under the guidance... read more

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

Biomarkers in Trauma, Injury and Critical Care (Biomarkers in Disease: Methods, Discoveries and Applications)

This handbook systematically presents biomarkers for traumatic injuries. The book covers topics such as traumatic brain injury, liver injury, burn severity, muscle heart damage, and acute inflammation in polytrauma and their... read more

Fluid Therapy for Critically Ill Adults with Sepsis

Fluid Therapy for Critically Ill Adults with Sepsis

Fluids are an important component of treating patients who are critically ill with sepsis. Although optimal fluid management in patients with sepsis remains uncertain, clinicians should consider the risks and benefits of... read more

Acute Kidney Injury in ICU Patients

Acute Kidney Injury in ICU Patients

Patients admitted to the intensive care unit are prone to various complications, one of which is acute kidney injury (AKI). The etiology of acute kidney injury can be multifactorial. Among the various causes, sepsis remains... read more

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Angiotensin-converting Enzyme 2 Polymorphisms and Susceptibility of Severe COVID-19

Science is digging for the varied presentation of COVID-19 patients exposed to the same risk factors, and medical conditions may be influenced by the presence of polymorphic genetic variants. This study investigated the link... read more

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon-Blowing Exercise Effect on Oxygen Saturation in COVID-19 Patients

Balloon therapy is an empirical example that patients with respiratory tract diseases can use to improve their daily care. The diaphragm and ribs are expanded and raised by the intercostal muscles, which are activated during... read more

Oxygen Support Needs in Children with RSV vs. COVID-19

Oxygen Support Needs in Children with RSV vs. COVID-19

Children with respiratory syncytial virus (RSV) had a higher risk of pneumonia, bronchiolitis, and a hospital stay of more than 4 days vs children with COVID-19 or influenza. Investigators compared demographic and clinical... read more

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Risk Factor for Superimposed Nosocomial BSI in Hospitalized COVID-19 Patients

Unmodified risk variables for nosocomial bloodstream infections (BSIs) included male sex and leukocytosis at admission. Using methylprednisolone and obtaining a cumulative dosage of dexamethasone were adjusted risk variables... read more

Bronchoscopy in ICU: A Practical Guide

Bronchoscopy in ICU: A Practical Guide

This practical guide focuses on Bronchoscopy in ICU. Bronchoscopy is one of the most commonly performed medical procedures, but is limited to the practice of a handful chest physicians and surgeons. The field of bronchoscopy... read more

Correlation of Common Carotid Artery Blood Flow Parameters With TTE-CO for Assessing Fluid Responsiveness After PLR Test in Critically Ill Patients

Correlation of Common Carotid Artery Blood Flow Parameters With TTE-CO for Assessing Fluid Responsiveness After PLR Test in Critically Ill Patients

The passive leg raising (PLR) test is a simple, non-invasive method of knowing fluid responsiveness by acting as an internal-fluid challenge. The PLR test coupled with a non-invasive assessment of stroke volume would be the... read more

The Song of the Cell: An Exploration of Medicine and the New Human

The Song of the Cell: An Exploration of Medicine and the New Human

In the late 1600s, Mukherjee sets the stage for an extraordinary tale. It revolves around two notable individuals: Robert Hooke, a renowned English polymath, and Antonie van Leeuwenhoek, an eccentric Dutch cloth-merchant.... read more

Choosing Wisely Interventions to Reduce Antibiotic Overuse

Choosing Wisely Interventions to Reduce Antibiotic Overuse

These real-world multicomponent interventions responding to physician pay-for-performance (P4P) incentives were associated with substantial reductions in antibiotic prescriptions for acute respiratory tract infections (ARTIs)... read more

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

Why We Can Thank a Polio Emergency for the Birth of Intensive Care

An outbreak of polio in 1950s Denmark led one hospital to pioneer mechanical ventilation, constant monitoring of vital signs and other innovations that are saving lives to this day. The COVID-19 pandemic has brought home... read more

The Autumn Ghost: How the Battle Against a Polio Epidemic Revolutionized Modern Medical Care

The Autumn Ghost: How the Battle Against a Polio Epidemic Revolutionized Modern Medical Care

"The Autumn Ghost" is a suspenseful and authoritative account that explores how the battle against a polio epidemic in the mid-20th century led to a revolution in medical care. Dr. Hannah Wunsch focuses on the autumn... read more

Comparison of ETA and BALF mNGS in Severe Pneumonia

Comparison of ETA and BALF mNGS in Severe Pneumonia

Our study showed that some differences in the microbiological diagnosis via endotracheal aspirate (ETA) mNGS and bronchoalveolar lavage fluid (BALF) metagenomic next-generation sequencing (mNGS) appear to exist. Clinicians... read more