Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Ingredient in aspirin combined with popular diabetes drug can turn off faulty protein that plays a key role in inflammatory diseases, such as rheumatoid arthritis. ... read more

Drug does not significantly reduce duration of mechanical ventilation for COPD patients

Drug does not significantly reduce duration of mechanical ventilation for COPD patients

Among mechanically ventilated patients with COPD, administration of the respiratory stimulant acetazolamide did not significantly reduce the duration of invasive mechanical ventilation.... read more

The Ability of ICU Physicians to Estimate Long-Term Prognosis in Survivors of Critical Illness

The Ability of ICU Physicians to Estimate Long-Term Prognosis in Survivors of Critical Illness

Prognoses estimated by physicians incorrectly predicted long-term survival and HRQoL in one-third of ICU survivors. Moreover, inaccurate prognoses were generally the result of overoptimistic expectations of outcome. Among... read more

Association Between mRNA Expression of CD74 and IL10 and Risk of ICU-acquired Infections

Association Between mRNA Expression of CD74 and IL10 and Risk of ICU-acquired Infections

Intensive care unit (ICU)-acquired infections (IAI) result in increased hospital and ICU stay, costs and mortality. To date, no biomarker has shown sufficient evidence and ease of application in clinical routine for the identification... read more

Sepsis National Hospital Inpatient Quality Measure

Sepsis National Hospital Inpatient Quality Measure

The Center for Medicare and Medicaid Services adopted the Early Management Bundle, Severe Sepsis/Septic Shock (SEP-1) performance measure to the Hospital Inpatient Quality Reporting Program in July 2015 to help address the... read more

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

Variation in Monitoring and Treatment Policies for Intracranial Hypertension in TBI

Substantial variation was found regarding monitoring and treatment policies in patients with Traumatic Brain Injury (TBI) and intracranial hypertension. The results of this survey indicate a lack of consensus between European... read more

Raising Sepsis Awareness

Raising Sepsis Awareness

Most recent parody created by ILAS (Brazil) aimed at health professionals with English subtitles. Share this video with your multidisciplinary teams because together we can overcome sepsis.... read more

Nutrition in Surgery and Critical Care

Nutrition in Surgery and Critical Care

DCRI Perioperative Nutrition focuses on the study of hospital-based treatments to improve preparation and recovery from surgery, major illness, and critical care. We put real science into improving patients' lives with interventions... read more

The Overlaps of Asthma or COPD with OSA

The Overlaps of Asthma or COPD with OSA

Asthma, chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are the most common respiratory disorders worldwide. Given demographic and environmental changes, prevalence for each is likely to increase. Some... read more

Antibiotic Prescription Fill Rates Declining

Antibiotic Prescription Fill Rates Declining

Since 2010, antibiotic prescription rates in the U.S. have been declining among the commercially insured population, falling 9 percent during this period. In this report, the Blue Cross Blue Shield Association, in partnership... read more

Sepsis Awareness Month

Sepsis Awareness Month

September is Sepsis Awareness month. To mark the occasion we invited Marijke Vroomen Durning, Director of Content at Sepsis Alliance, to tell us more about Sepsis, the organization’s work, and the importance of raising... read more

Post-ICU Psychological Morbidity in Very Long ICU Stay Patients with ARDS and Delirium

Post-ICU Psychological Morbidity in Very Long ICU Stay Patients with ARDS and Delirium

Delirium was associated with memory impairment and PTSS-14 scores suggestive of PTSD, but not illness severity. 181 subjects were included. Illness severity did not correlate with delirium duration. On logistic regression,... read more

Biomarkers in AKI: That’s All the Story?

Biomarkers in AKI: That’s All the Story?

We would like to add to the recent editorial by McMahon on biomarkers of acute kidney injury (AKI), with a specific focus on biomarkers in the clinical setting of cardiac surgery-associated AKI (CSA-AKI). We agree with McMahon... read more

CDC Urges Early Recognition, Prompt Treatment of Sepsis

CDC Urges Early Recognition, Prompt Treatment of Sepsis

The Centers for Disease Control and Prevention today launched Get Ahead of Sepsis, an educational initiative to protect Americans from the devastating effects of sepsis. This initiative emphasizes the importance of early... read more

Cochrane Strategy to 2020

Cochrane Strategy to 2020

Strategy to 2020 aims to put Cochrane evidence at the heart of health decision-making all over the world. It defines how we intend to accomplish this and provides a framework for Cochrane's future decision-making, helping... read more

Emergency Preparedness in Healthcare

Ludwig Lin, MD, speaks with Grete Porteous, MD, about emergency preparedness in healthcare and the role of critical care personnel in catastrophic situations. Dr. Porteous advises on how to prepare institutions for disaster... read more

Ultrasound-guided Central Venous Catheter Placement

Ultrasound-guided Central Venous Catheter Placement

Ultrasound-guided central venous catheter placement: a structured review and recommendations for clinical practice. Although placement of a central venous catheter (CVC) is a routine procedure in intensive care medicine and... read more