Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Sodium Bicarbonate Versus Sodium Chloride for Preventing Contrast-Associated AKI

Except for urinary pH, none of the outcomes differed between the two groups. Among ICU patients with stable renal function, the benefit of using sodium bicarbonate rather than isotonic sodium chloride for preventing contrast-associated... read more

How survival of cancer patients in critical care has improved in the last 3 decades

How survival of cancer patients in critical care has improved in the last 3 decades

Comprehensive care for critically ill patients with cancer is a collaborative effort, and close cooperation between oncology as well as palliative and critical care is essential. Collaborative decision making is a cornerstone... read more

Thrombocytosis in the ED

Thrombocytosis in the ED

Both reactive thrombocytosis and clonal thrombocytosis may be associated with vasomotor symptoms. The key difference is that thrombotic and bleeding events are much more common in myeloproliferative thrombocytosis, whereas... read more

Central Line Versus Peripheral IV Flow Rates In Resuscitation

Central Line Versus Peripheral IV Flow Rates In Resuscitation

The indications for central venous catheters (CVCs) include invasive hemodynamic monitoring, transvenous cardiac pacing, hemodialysis, lack of peripheral venous access, administration of vasopressors, nutritional support,... read more

Portable Imaging Device Assesses Tissue Oxygenation

Portable Imaging Device Assesses Tissue Oxygenation

A handheld, battery operated diagnostic imaging device measures oxygen saturation (O2Sat) and other measures in superficial tissues for patients with potential circulatory compromise. The HyperView is intended for use by... read more

Interventions to improve antibiotic prescribing practices for hospital inpatients

Interventions to improve antibiotic prescribing practices for hospital inpatients

This review includes 221 studies (58 RCTs, and 163 NRS). Most studies were from North America (96) or Europe (87). The remaining studies were from Asia (19), South America (8), Australia (8), and the East Asia (3). We found... read more

Catheter System Drains Recurrent Pleural Effusions

Catheter System Drains Recurrent Pleural Effusions

A novel catheter system enables patients to drain pleural fluid at home, instead of requiring them to return to the hospital for thoracentesis. The PleurX catheter system consists of a catheter that is inserted in the chest... read more

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Deaths After PCI: Study Compares Public Reporting Models Both With and Without Cardiogenic Shock

Three distinct models for reporting risk-adjusted mortality rates among hospitals and physicians performing PCI in New York State demonstrate a high degree of agreement, despite variation in how they handle the inclusion... read more

Crizanlizumab use lowers rates of sickle cell crises

Crizanlizumab use lowers rates of sickle cell crises

Patients with sickle cell disease treated with high-dose crizanlizumab experienced lower annualized rates of sickle cell crisis compared to placebo treatment, regardless of their baseline use of hydroxyurea. Those treated... read more

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

Thromboprophylaxis after Knee Arthroscopy and Lower-Leg Casting

The results of our trials showed that prophylaxis with low-molecular-weight heparin for the 8 days after knee arthroscopy or during the full period of immobilization due to casting was not effective for the prevention of... read more

Social Media Helps Forecast Outbreak Transmission Patterns

Social Media Helps Forecast Outbreak Transmission Patterns

A new study suggests then when epidemiological data are scarce, social media and Internet reports can be reliable tools for forecasting infectious disease outbreaks. Researchers at Georgia State University and the U.S. National... read more

Biopsy first: Lessons learned from CALGB 140503

Biopsy first: Lessons learned from CALGB 140503

In a carefully monitored cohort of patients with suspected small NSCLC <2 cm, a substantial number are misdiagnosed (benign nodules) or understaged. These patients may not have benefited from a thoracic surgical procedure.... read more

Manufacturer guidelines fall short for endoscope reprocessing

Manufacturer guidelines fall short for endoscope reprocessing

A just-published study finds that current endoscopic manufacturer cleaning instructions for a wide range of GI, urological and respiratory devices used in diagnostic procedures still fail to protect patients from the risk... read more

Hydrocortisone Fails to Prevent Septic Shock

Hydrocortisone Fails to Prevent Septic Shock

Hydrocortisone failed to reduce the risk of septic shock in severe sepsis patients in recent research, though its authors held out hope that a larger study could show a better result. Current guidelines recommend hydrocortisone... read more

Six myths promoted by the new surviving sepsis guidelines

Six myths promoted by the new surviving sepsis guidelines

The Rivers trial and the Surviving Sepsis Campaign popularized sepsis protocols, which saved lives. Massive accomplishment. However, that doesn’t validate the individual components of early goal-directed therapy. Any protocol... read more

Benefits and harms of duloxetine for treatment of stress urinary incontinence

Benefits and harms of duloxetine for treatment of stress urinary incontinence

Duloxetine was significantly better than placebo in terms of percentage change in weekly incontinence episodes (mean difference - 13.56%, 95% confidence interval [CI] -21.59% to -5.53%) and change in Incontinence Quality... read more

Scientist Invents Hand-Held Breath Monitor to Detect Flu

Scientist Invents Hand-Held Breath Monitor to Detect Flu

Dr. Perena Gouma, a professor at the University of Texas at Arlington, has published an article in the journal Sensors that describes her invention of a hand-held breath monitor designed to detect the flu virus. Gouma’s... read more