Caring for the Sickest COVID-19 Patients: An ICU Story

Caring for the Sickest COVID-19 Patients: An ICU Story

In an article for the latest issue of Stanford Medicine magazine, I provide a glimpse into the journey Free and his front-line Stanford Health Care colleagues took -- from Day 1 through the following weeks and months -- to... read more

Expert Consensus on Methodology for Conducting and Reporting Echocardiography Research Studies

Expert Consensus on Methodology for Conducting and Reporting Echocardiography Research Studies

Echocardiography is a common tool for cardiac and hemodynamic assessments in critical care research. However, interpretation (and applications) of results and between-study comparisons are often difficult due to the lack... read more

Early prediction of impending septic shock in children using age-adjusted Sepsis-3 criteria

Early prediction of impending septic shock in children using age-adjusted Sepsis-3 criteria

Sepsis is a syndrome which afflicts both adults and children, with many disease courses and diverse outcomes. Understanding of sepsis pathophysiology has changed over time; the Sepsis-3 criteria define sepsis in adults as... read more

COVID-19 and ARDS: The Baby Lung Size Matters

COVID-19 and ARDS: The Baby Lung Size Matters

COVID-19 in its initial manifestations has strikingly peculiar characteristics (e.g., hypoxemia with vasocentric injury and high gas lung volume), is so evident that atypical ARDS should not be a matter of further discussion.... read more

What’s new about pulmonary hyperinflation in mechanically ventilated critical patients

What’s new about pulmonary hyperinflation in mechanically ventilated critical patients

Pulmonary hyperinflation is the increase in the relaxation volume of the respiratory system at the end of a tidal expiration (end-expiratory volume). This can occur due to a number of factors, acting alone or in combination,... read more

Fishman’s Pulmonary Diseases and Disorders

Fishman’s Pulmonary Diseases and Disorders

Since 1980, Fishman's Pulmonary Diseases and Disorders has delivered unparalleled coverage of pulmonary medicine and the underlying basic and applied science upon which clinical practice is based. The Fifth Edition, with... read more

Sick Meningitis, POCUS for Pneumoperitoneum, and Treatment of CHS

Sick Meningitis, POCUS for Pneumoperitoneum, and Treatment of CHS

Today on the emDocs cast with Brit Long, MD (@long_brit) and Manpreet Singh, MD (@MprizzleER) we cover three posts: the sick meningitis patient, ultrasound for pneumoperitoneum, and treatment of cannabiniod hyperemesis syndrome. Part... read more

Mechanical Ventilators for Non-invasive Ventilation

Mechanical Ventilators for Non-invasive Ventilation

This book analyzes and describes the whole spectrum of technical elements related with non-invasive mechanical ventilators technologies, ventilator modes and complementary technologies for correct interpretation and clinical... read more

Predictors of QT Interval Prolongation in Critically-ill Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine

Predictors of QT Interval Prolongation in Critically-ill Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine

Hydroxychloroquine (HCQ) has been described as a potential treatment for SARS-CoV-2 infection. However, there are safety concerns regarding its QT interval and pro-arrhythmic effects. This trial aimed to determine the... read more

CDC cuts COVID-19 Quarantine Recommendation

CDC cuts COVID-19 Quarantine Recommendation

The CDC released new COVID-19 guidelines Dec. 2, reducing the previous 14-day quarantine recommendation for people who were exposed to 10 days without symptoms, reports CBS. The recommendation is further reduced to seven... read more

Myorelaxants in ARDS patients

Myorelaxants in ARDS patients

Neuromuscular blocking agents (NMBAs) inhibit patient-initiated active breath and the risk of high tidal volumes and consequent high transpulmonary pressure swings, and minimize patient/ ventilator asynchrony in acute respiratory... read more

Failing to Learn and Learning to Fail

Failing to Learn and Learning to Fail

Last week saw the publication of yet another damning report shining a spotlight on the culture of cover up and denial in our healthcare system. Bill Kirkup’s report—”The Life and Death of Elizabeth Dixon: A Catalyst... read more

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

ARDS, first described in 1967, is the commonest form of acute severe hypoxemic respiratory failure. Despite considerable advances in our knowledge regarding the pathophysiology of ARDS, insights into the biologic mechanisms... read more

Airway closure, more harmful than atelectasis in intensive care?

Airway closure, more harmful than atelectasis in intensive care?

Since the mid-1980s, atelectasis has been demonstrated during anesthesia in lung healthy subjects and in intensive care patients suffering from acute respiratory failure and requiring ventilator support. In the latter... read more

Assessment of Cancer Therapy Evaluation Program Advocacy and Inclusion of People With HIV in Anti–PD1/PDL1 Trials

Assessment of Cancer Therapy Evaluation Program Advocacy and Inclusion of People With HIV in Anti–PD1/PDL1 Trials

This study identified encouraging trends in the inclusion of PLWH in anti–PD1/PDL1 cancer trials that occurred in the period following the initiation of CTEP advocacy. Work is needed to examine what impact this will have... read more

CDC to vote on who gets COVID-19 vaccine priority in emergency meeting

CDC to vote on who gets COVID-19 vaccine priority in emergency meeting

Ahead of a COVID-19 vaccine authorization, the CDC's Advisory Committee for Immunization Practices plans to vote during a Dec. 2 emergency meeting on who should be the first to receive a vaccine, reports CNN. The CDC... read more

Missouri physician starts petition calling for governor to implement mask mandate

Missouri physician starts petition calling for governor to implement mask mandate

Michah Luderer, MD, PhD, internal medicine resident at St. Louis based-Barnes Jewish Hospital recently started a petition urging Gov. Mike Parson to issue a statewide mask mandate, reports local CBS affiliate KMOV. "We're... read more