Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation

Effect of Home Noninvasive Ventilation With Oxygen Therapy vs Oxygen Therapy Alone on Hospital Readmission or Death After an Acute COPD Exacerbation

In this randomized clinical trial of 116 patients, the addition of home noninvasive ventilation significantly prolonged time to readmission or death from 1.4 months to 4.3 months. Among patients with persistent hypercapnia... read more

Clinical Implications of Sarcopenia on Decreased Bone Density in Men With COPD

Clinical Implications of Sarcopenia on Decreased Bone Density in Men With COPD

Sarcopenia and osteoporosis are systemic features of COPD. The present study investigated the association between sarcopenia and osteopenia/osteoporosis and the factors associated with low bone mineral density (BMD) in men... read more

Using Ventilator to Control Oxygen May Be COPD Game-changer

Using Ventilator to Control Oxygen May Be COPD Game-changer

Using a ventilator to control the level of supplemental oxygen a chronic obstructive pulmonary disease (COPD) patient receives halved patients' trips to the hospital from disease flare-ups, according to a clinical trial. British... read more

Effect of Home NIV on Outcomes After Acute COPD Exacerbation

Effect of Home NIV on Outcomes After Acute COPD Exacerbation

This randomized clinical trial compares the effects of home oxygen therapy with vs without home noninvasive ventilation (NIV) on time to readmission or death in patients with persistent hypercapnia after an acute chronic... read more

We're Bad at Death. Can We Talk?

We're Bad at Death. Can We Talk?

Despite growing recognition that more care isn't necessarily better care, particularly at the end of life, many Americans still receive an enormous dose of medicine in their final days. On average, patients make 29 visits... read more

Bi-level Ventilation: Who Needs it and Who Doesn't?

Bi-level Ventilation: Who Needs it and Who Doesn't?

Bi-level ventilation is commonly used in patients with respiratory failure in the emergency department. This is a brief review of the indications for bi-level ventilation as well as a review of the complications of this popular... read more

Extra Corporeal Carbon Dioxide Removal

Extra Corporeal Carbon Dioxide Removal

In patients with chronic obstructive airway disease and hypercapneic acidosis, who are failing non-invasive ventilation, does extra corporeal carbon dioxide removal compared to non-invasive ventilation alone, reduce the... read more

Lung Microbiome: Key to Respiratory Ills?

Lung Microbiome: Key to Respiratory Ills?

Recently, JAMA discussed this research and its potential clinical applications with 2 experts on the front lines, Jack Gilbert, PhD, a microbial ecologist at the University of Chicago and director of its new Microbiome Center... read more

Addition of vitamin B12 to exercise training improves cycle ergometer endurance in advanced COPD patients

Addition of vitamin B12 to exercise training improves cycle ergometer endurance in advanced COPD patients

Vitamin B12 is essential in the homocysteine, mitochondrial, muscle and hematopoietic metabolisms, and its effects on exercise tolerance and kinetics adjustments of oxygen consumption (V'O2p) in rest-to-exercise transition... read more

Clinical review: The ABC of weaning failure

Clinical review: The ABC of weaning failure

About 20% to 30% of patients are difficult to wean from invasive mechanical ventilation. The pathophysiology of difficult weaning is complex. Accordingly, determining the reason for difficult weaning and subsequently developing... read more

Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline

Management of COPD exacerbations: a European Respiratory Society/American Thoracic Society guideline

This document provides clinical recommendations for treatment of chronic obstructive pulmonary disease (COPD) exacerbation. This recommendation places a high value on improving clinical outcomes and a lower value on the burden... read more

Sepsis Readmissions Compared With Other Medical Conditions

Sepsis Readmissions Compared With Other Medical Conditions

This study uses data from a US readmissions database to assess whether sepsis hospitalizations account for a higher proportion of unplanned 30-day readmissions than hospitalizations for acute myocardial infarction, heart... read more

Exacerbation of COPD: Causes, Warning Signs, and Treatment

Exacerbation of COPD: Causes, Warning Signs, and Treatment

What is a COPD exacerbation and what are the main causes? Learn about what the symptoms are and what is suggested to try to prevent COPD. Most commonly referred to as COPD, the term describes emphysema and chronic bronchitis.... read more

COPD Patients in US Often Skip Medications

COPD Patients in US Often Skip Medications

People with chronic obstructive pulmonary disease (COPD) often have other chronic conditions, like heart disease, and those who are poor about keeping up with treatments for these comorbidites are also less likely to adhere... read more