Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia

Effect of a National Standard for Deteriorating Patients on Intensive Care Admissions Due to Cardiac Arrest in Australia

The main objective of this study is to assess whether a national standard for improving care of deteriorating patients affected ICU admissions following cardiac arrests from hospital wards. Introducing a national standard... read more

TAC on Computed Tomography and the Risk of COPD Progression

TAC on Computed Tomography and the Risk of COPD Progression

Total Airway Count (TAC) may reflect the airway-related disease changes that accumulate in the “quiet” zone in early/mild Chronic Obstructive Pulmonary Disease (COPD), indicating that TAC acquired with commercially available... read more

Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction

Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction

Effect of Individualized vs Standard Blood Pressure Management Strategies on Postoperative Organ Dysfunction Among High-Risk Patients Undergoing Major Surgery. Among patients predominantly undergoing abdominal surgery who... read more

Severity of Illness Scores May Misclassify Critically Ill Obese Patients

Severity of Illness Scores May Misclassify Critically Ill Obese Patients

Severity of illness scores rest on the assumption that patients have normal physiologic values at baseline and that patients with similar severity of illness scores have the same degree of deviation from their usual state.... read more

The Contents of a Patient Diary and its Significance in the ICU

The Contents of a Patient Diary and its Significance in the ICU

The aim of this study was to describe the contents of a patient diary and its significance for persons cared for in an ICU. What formerly critically ill patients appreciate most about the diary is that the diary is personally... read more

Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation

Early Identification of Acute Respiratory Distress Disorder in the Absence of Positive Pressure Ventilation

Almost all patients with pulmonary bilateral infiltrates and a PaO2/FIO2 less than or equal to 300 mm Hg under standard oxygen fulfilled the acute respiratory distress syndrome criteria under noninvasive ventilation within... read more

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

A Comparison of the qSOFA and SIRS Criteria for the Diagnosis of Sepsis and Prediction of Mortality

Several studies were published to validate quick-SOFA (qSOFA), namely in comparison with Systemic Inflammatory Response Syndrome (SIRS) criteria. We performed a systematic review and a meta-analysis with the aim of comparing... read more

Effect of Boarding on Mortality in ICUs

Effect of Boarding on Mortality in ICUs

Mortality increased with boarding of critically ill patients. Further research is needed to identify safer practices for managing patients during periods of high ICU occupancy. The study population consisted of 8,429 patients... read more

Dexmedetomidine-Associated Hyperthermia

Dexmedetomidine-Associated Hyperthermia

Dexmedetomidine-associated hyperthermia: a retrospective cohort study of intensive care unit admissions between 2009 and 2016. Dexmedetomidine-associated hyperthermia has not been previously studied. Analysis is warranted... read more

Regional Variation of Computed Tomographic Imaging and the Risk of Nephrectomy

Regional Variation of Computed Tomographic Imaging and the Risk of Nephrectomy

In this analysis of 306 hospital referral regions, regional CT risk was significantly correlated with nephrectomy, and scanning an additional 1000 Medicare beneficiaries was associated with 4 additional nephrectomies. Beneficiaries... read more

Predicting the Hemodynamic Response to Prone Positioning

Predicting the Hemodynamic Response to Prone Positioning

Graphical models of physiology are heuristically appealing as they facilitate qualitative conclusions at the bedside of the critically ill. Historically, the Rahn diagram has portrayed the physiology of the lungs, chest wall... read more

Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

While guidance on statistical principles for clinical trials exists, there is an absence of guidance covering the required content of statistical analysis plans (SAPs) to support transparency and reproducibility. Recommendations... read more

The Effect of ICU Out-of-Hours Admission on Mortality

The Effect of ICU Out-of-Hours Admission on Mortality

Adjusted risk of death for ICU admission was greater over the weekends compared with weekdays. The absence of a dedicated intensivist on-site overnight may be associated with increased mortality for acute admissions. These... read more

Improving Handovers By Learning From Ferrari Team

Improving Handovers By Learning From Ferrari Team

We were able to improve our vulnerable processes by translating good practice found in two industries – aviation and motor racing – into healthcare. We were able to do this by taking into account the subtle complexities... read more