Checklist for Early Recognition and Treatment of Acute Illness and Injury

Checklist for Early Recognition and Treatment of Acute Illness and Injury

A quality-improvement intervention with remote simulation training to implement a decision support tool was associated with decreased nonadherence to daily care processes, shorter length of stay, and decreased mortality. The... read more

New Approaches Reduces Inappropriate Antibiotic Usage

New Approaches Reduces Inappropriate Antibiotic Usage

A UC Davis study of 9 emergency departments and urgent care centers in California and Colorado found educating physicians and patients about safe antibiotic use can cut overuse by 30%. The study, funded under a contract from... read more

Superbugs Pose a Dangerous, $65 Billion Threat to the US Health-Care System

Superbugs Pose a Dangerous, $65 Billion Threat to the US Health-Care System

A new report released Wednesday from the OECD estimates that antimicrobial resistant infection is on track to kill 30,000 Americans per year by 2050. The financial cost to the 33 developed countries included in the study... read more

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock

Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock. Despite a progressive increase in mortality... read more

Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

Antimicrobials for the Treatment of Drug-Resistant Acinetobacter Baumannii Pneumonia in Critically Ill Patients

This Bayesian network meta-analysis demonstrated the comparative effectiveness of fifteen antimicrobial treatments for drug-resistant A. baumannii pneumonia in critically ill patients. For survival benefit, SUL appears to... read more

Role of Combination Antimicrobial Therapy for Vancomycin‐Resistant Enterococcus faecium Infections

Role of Combination Antimicrobial Therapy for Vancomycin‐Resistant Enterococcus faecium Infections

Enterococcus species are the second most common cause of nosocomial infections in the United States and are particularly concerning in critically ill patients with preexisting comorbid conditions. Rising resistance to antimicrobials... read more