Critical care ultrasonography in acute respiratory failure

Critical care ultrasonography in acute respiratory failure

CCUS combining CCE and chest ultrasonography rapidly provides valuable information in patients presenting with ARF. A pragmatic and systematic applied protocol may first evaluate how aerated is the lung and whether there... read more

Airway Driving Pressure and Lung Stress in ARDS Patients

Airway Driving Pressure and Lung Stress in ARDS Patients

Since the first description of acute respiratory distress syndrome (ARDS) in the 1960s, numerous studies have sought the optimal tidal volume, positive end-expiratory pressure, plateau pressure, and inspired fraction of oxygen... read more

Severe Adult ARDS Prediction Models

Severe Adult ARDS Prediction Models

Outcomes and survival prediction models for severe adult acute respiratory distress syndrome treated with extracorporeal membrane oxygenation. Although the use of ECMO for severe refractory ARDS has markedly increased since... read more

End-Inspiratory Pause Prolongation in ARDS Patients

End-Inspiratory Pause Prolongation in ARDS Patients

Prolonging EIP allowed a significant decrease in Vt without changes in PaCO2 in passively ventilated ARDS patients. This produced a significant decrease in plateau pressure and driving pressure and significantly increased... read more

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more

Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit

Apnoeic oxygenation via high-flow nasal cannula oxygen combined with non-invasive ventilation preoxygenation for intubation in hypoxaemic patients in the intensive care unit

A novel strategy for preoxygenation in hypoxaemic patients, adding HFNC for apnoeic oxygenation to NIV prior to orotracheal intubation, may be more effective in reducing the severity of oxygen desaturation than the reference... read more

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

Ten trials met the inclusion criteria for this review (n = 1658 participants). We found five trials to be at low risk of bias and five to be at moderate risk of bias.... read more

Devil in the details: Endotracheal tube depth

Devil in the details: Endotracheal tube depth

According to Napoleon, "the moment of greatest vulnerability is the instant immediately after victory." In airway management, this instant occurs immediately after placement of the endotracheal tube.... read more

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome

In sepsis-associated ARDS, hydrocortisone treatment was associated with a significant improvement in pulmonary physiology, but without a significant survival benefit.... read more

Utilising the immune system in the fight against sepsis – On Medicine

Utilising the immune system in the fight against sepsis – On Medicine

In this blog, Dr. Naoshi Takeyama, Senior Editor of Journal of Intensive Care, discusses about how knowledge of immuno-oncology can also be applied to strategies for managing sepsis and severe trauma.... read more