Early Hemorrhage Control and Management of Trauma-induced Coagulopathy

Early Hemorrhage Control and Management of Trauma-induced Coagulopathy

Trauma resuscitation should focus on early goal-directed therapy with use of viscoelastic hemostatic assays while initially applying a ratio 1:1:1 driven transfusion therapy (with red blood cells, plasma and platelets) in... read more

Bleeding During Percutaneous Dilatational Tracheostomy – What to do while waiting for the surgeon?

Bleeding During Percutaneous Dilatational Tracheostomy – What to do while waiting for the surgeon?

A patient suffered significant bleeding during an attempt at percutaneous dilatational tracheostomy due to an aberrant anterior jugular vein. Bleeding was controlled with pressure temporarily, but quickly returned necessitating... read more

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

The post-thrombotic syndrome frequently develops in patients with proximal deep-vein thrombosis despite treatment with anticoagulant therapy. Pharmacomechanical catheter-directed thrombolysis (hereafter "pharmacomechanical... read more

Should All Massively Transfused Patients Be Treated Equally?

Should All Massively Transfused Patients Be Treated Equally?

Although balanced resuscitation has become integrated into massive transfusion practice, there is a paucity of evidence supporting the delivery of high ratios of plasma and platelet to RBCs in the nontrauma setting. This... read more

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Venous Thromboembolism Prophylaxis in Major Orthopedic Surgery

Few head-to-head treatment comparisons have sufficient evidence. Most studies evaluated low molecular weight heparin (LMWH), not low-risk interventions (such as aspirin and mechanical devices); most reported on total deep... read more

Thrombocytosis in the ED

Thrombocytosis in the ED

Both reactive thrombocytosis and clonal thrombocytosis may be associated with vasomotor symptoms. The key difference is that thrombotic and bleeding events are much more common in myeloproliferative thrombocytosis, whereas... read more

Uncontrolled Bleeding Stopped By Injectable Viscous Hydrogel

Uncontrolled Bleeding Stopped By Injectable Viscous Hydrogel

A new study describes a novel embolic agent for endovascular embolization procedures that has a hemostatic activity comparable to that of metallic coils, the current gold standard. The nanocomposite STBs are injected through... read more

Examining Pantoprazole or Placebo for Stress Ulcer Prophylaxis

Examining Pantoprazole or Placebo for Stress Ulcer Prophylaxis

Pantoprazole is frequently administered to critically ill patients for prophylaxis against gastrointestinal bleeding. However, comparison to placebo has been inadequately evaluated, and pantoprazole has the potential to cause... read more

Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches

Todd Fraser, MD, speaks with Scott Kaatz, DO, FACP, SFHM, about his talk given at the 45th Critical Care Congress on, Bleeding Management and Reversal Strategies for the DOAC Patient: New and Future Approaches. Dr. Kaatz... read more

Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before

Patients benefit from tranexamic acid in surgery, withholding blood pressure meds before

Four innovative studies exploring ways to reduce complications related to heart surgery or minimize patient mortality due to risks associated with low blood pressure and surgery.... read more

More NOAC Comparisons See More Bleeding With Rivaroxaban: Is the ‘Writing on the Wall’?

More NOAC Comparisons See More Bleeding With Rivaroxaban: Is the ‘Writing on the Wall’?

Evidence is mounting, albeit from observational studies, that while all of the non-vitamin K antagonist oral anticoagulants (NOACs) appear to have similar efficacy in terms of stroke reduction in atrial fibrillation, they... read more