Learning to talk about death should start early in doctors' careers

At first glance, physicians’ poor understanding of death and the process of dying is baffling, since they are supposed to be custodians of health across the lifespan. Look deeper, though, and it may reflect less the attitudes... read more

Learning to talk about death should start early in doctors' careers

Palliative care from diagnosis to death

Evidence is growing that people can benefit from palliative care earlier in their illness, say Scott Murray and colleagues, but care must be tailored to different conditions. Many people still associate palliative care with... read more

Palliative care from diagnosis to death

How survival of cancer patients in critical care has improved in the last 3 decades

Comprehensive care for critically ill patients with cancer is a collaborative effort, and close cooperation between oncology as well as palliative and critical care is essential. Collaborative decision making is a cornerstone... read more

How survival of cancer patients in critical care has improved in the last 3 decades

Biopsy first: Lessons learned from CALGB 140503

In a carefully monitored cohort of patients with suspected small NSCLC <2 cm, a substantial number are misdiagnosed (benign nodules) or understaged. These patients may not have benefited from a thoracic surgical procedure.... read more

Biopsy first: Lessons learned from CALGB 140503

Characterizing Hydrogels for use in drug delivery systems

The delivery of drugs to a precise location at the desired concentration without causing toxic effects to the rest of the body has been a challenge to biomedical science for many years. Although several approaches have been... read more

Characterizing Hydrogels for use in drug delivery systems

Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors

A case study published in the December 29 issue of the New England Journal of Medicine outlines the results of a patient treated with his own genetically modified CAR-T cells, using central memory T cells, a stem-cell-like... read more

Patient Achieves Remission With CAR-T Cell Therapy for Aggressive Brain Tumors

Epstein-Barr risk increased by Immune Molecule Deficiency

Researchers from the National Institutes of Health National Institute of Allergy and Infectious Diseases, or NIAID, have found a genetic immune disorder causing increased risk and poor control of Epstein-Barr virus and EBV-associated... read more

Epstein-Barr risk increased by Immune Molecule Deficiency

Study shows Tumor cells move differently than normal cells

Drexel University researchers have found that some tumor cells are unable to move like healthy cells, which could impact the way cancer is spread and treated. The team found that certain tumor cells called fibrosarcoma cannot... read more

Study shows Tumor cells move differently than normal cells

Upright CT for lung cancer therapy planning used at Chicago Proton Center

The Northwestern Medicine Chicago Proton Center will be the first proton center in the U.S. to use P-Cure new P-ARTIS CT on patients being treated for lung cancer. Traditionally, patients lie flat on their backs during CT... read more

Upright CT for lung cancer therapy planning used at Chicago Proton Center

Quality of Outpatient Care Delivered to Adults in USA

This cross-sectional survey study measures changes in outpatient quality and patient experience in the United States from 2002 to 2013 to determine whether efforts to improve outpatient quality have been successful. Three... read more

Quality of Outpatient Care Delivered to Adults in USA

Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

The researchers found that the drugs were well tolerated, with no serious adverse events reported. The indexed left ventricular end diastolic volume increased in patients treated with perindopril, bisoprolol, and placebo... read more

Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History

Having a history of cancer does not worsen outcomes for patients with STEMI who undergo primary PCI and should not be a barrier to revascularization and optimal therapy.... read more

Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History

Value of Expedited Drug Approvals for Cancer Care

This study examines potential benefits of cancer drugs approved by the FDA on the basis of surrogate endpoints.... read more

Value of Expedited Drug Approvals for Cancer Care

USPSTF: Don’t Screen Asymptomatic Adults for Thyroid Cancer

After reviewing studies on the benefits and harms of screening and treatment for thyroid cancer, a newly released U.S. Preventive Services Task Force draft statement recommends against screening asymptomatic adults for the... read more

USPSTF: Don’t Screen Asymptomatic Adults for Thyroid Cancer

Successfully treating genetically determined autoimmune enteritis

Using targeted immunotherapy, doctors have succeeded in curing a type of autoimmune enteritis caused by a recently discovered genetic mutation.... read more

Successfully treating genetically determined autoimmune enteritis

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

CDC estimates preventable deaths from 5 leading causes

The federal Centers for Disease Control and Prevention released data naming the five leading causes of death among Americans under age 80 for 2014.... read more

CDC estimates preventable deaths from 5 leading causes