Tag: coronavirus
Epidemiology and microbiology of ventilator-associated pneumonia in COVID-19 patients
The COVID-19 pandemic is responsible for many hospitalizations in intensive care units (ICU), with widespread use of invasive mechanical ventilation (IMV) which exposes patients to the risk of ventilator-associated pneumonia... read more
Central and peripheral nervous system complications of COVID-19
CNS and PNS complications were common in hospitalized COVID-19 patients, particularly in the ICU, and often attributable to critical illness. When COVID-19 was the primary cause for neurological disease, no signs of viral... read more
Duty of Care: One NHS Doctor’s Story of Courage and Compassion on the COVID-19 Frontline
The first book to tell the full story of the Covid-19 pandemic, from an NHS doctor working inside hospitals to save lives and combat the virus on the front line. Duty of Care is the first book to tell the full story of... read more
Effect of a Single High Dose of Vitamin D3 on Hospital LOS in Patients with COVID-19
Among hospitalized patients with COVID-19, a single high dose of vitamin D3, compared with placebo, did not significantly reduce hospital length of stay. The findings do not support the use of a high dose of vitamin D3 for... read more
The Plague Cycle: The Unending War Between Humanity and Infectious Disease
For four thousand years, the size and vitality of cities, economies, and empires were heavily determined by infection. Striking humanity in waves, the cycle of plagues set the tempo of civilizational growth and decline, since... read more
Study finds genetic clues to pneumonia risk and COVID-19 disparities
Researchers at Vanderbilt University Medical Center and colleagues have identified genetic factors that increase the risk for developing pneumonia and its severe, life-threatening consequences. Their findings, published... read more
Human ACE2 peptide-mimics block SARS-CoV-2 pulmonary cells infection
The current pandemic originated by SARS-CoV-2 causes an unprecedented health crisis. The medical world has found itself helpless in the face of this virus, having to deal with the absence of specific effective treatment.... read more
Is chloroquine or hydroxychloroquine useful in treating people with COVID-19, or in preventing infection in people who have been exposed to the virus?
COVID-19 is an infectious respiratory disease caused by a coronavirus called SARS-CoV-2. If the infection becomes severe, people may need intensive care and support in hospital, including mechanical ventilation. Drugs... read more
Barotrauma in Mechanically-ventilated Patients with COVID-2019
Within the limits of a survey, patients with COVID-19 might be at high risk for barotrauma during invasive (and allegedly lung-protective) mechanical ventilation. The response rate was 38/61 (62%). The incidence of... read more
Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients
Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve.... read more
RECOVERY trial shows tocilizumab reduces deaths in patients hospitalised with COVID-19
The NIHR-supported RECOVERY trial has shown that tocilizumab - an anti-inflammatory rheumatoid arthritis treatment - reduces the risk of death for hospitalised patients with severe COVID-19. Researchers also found that... read more
Surviving Sepsis Campaign Guidelines on the Management of Adults with COVID-19 in the ICU
The Surviving Sepsis Campaign Coronavirus Disease 2019 panel issued several recommendations to guide healthcare professionals caring for adults with critical or severe coronavirus disease 2019 in the ICU. Based on a living... read more
COVID-19 and VILI: Mechanical Power Measurement
The COVID-19 pandemic has increased the need for a bedside tool for lung mechanics assessment and ventilator-induced lung injury (VILI) monitoring. Mechanical power is a unifying concept including all the components which... read more
COVID-19 Awake Proning – All Hype?
In this prospective meta-analysis of observational studies of patients with acute hypoxemic respiratory failure due to COVID-19, APP did not result in lower intubation or mortality rates, despite reported improvements in... read more
Mediastinal lymphadenopathy may predict 30-day mortality in COVID-19 patients
Along with older age and consolidation pattern,enlarged mediastinal lymphadenopathy was found to be an independent predictor of 30-day mortality in patients with COVID-19. Although enlarged mediastinal lymphadenopathy... read more
COVID-19: Clinical manifestations of blood cell parameters and inflammatory factors
CRP and Lymphocyte count (LYM#) showed strong correlation with disease progression, suggesting that these parameters could be used to monitor changes in patient condition. 92 patients with confirmed COVID-19 at Jingzhou... read more
Covid PPE: How healthcare workers came to feel expendable
Over the course of the coronavirus pandemic, there have been hundreds of deaths among healthcare staff from Covid and many thousands off sick or self-isolating, but many hospital staff say they still don't feel properly protected... read more
