Awake Proning for COVID-19

Awake Proning for COVID-19

Prone positioning improves oxygenation in spontaneous breathing nonintubated patients with hypoxemic acute respiratory failure: A retrospective study. This is a retrospective case series describing 15 non-intubated patients... read more

High Risk of Thrombosis in Patients with Severe COVID-19

High Risk of Thrombosis in Patients with Severe COVID-19

Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications. Higher anticoagulation targets than in usual critically ill patients should therefore... read more

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

Rapid Development of an Inactivated Vaccine Candidate for COVID-19

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health crisis. There are currently no SARS-CoV-2-specific... read more

The Pandemic Is a Perfect Storm for ICU Delirium

The Pandemic Is a Perfect Storm for ICU Delirium

Spending time in the ICU, especially for anyone with COVID-19, is a dangerous, physically taxing experience: Only the most seriously ill patients land in intensive care, where many undergo a number of complex medical treatments... read more

Pathological Inflammation in Patients with COVID-19

Pathological Inflammation in Patients with COVID-19

The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than 200,000 deaths worldwide. Several studies have now established that the hyperinflammatory response induced by SARS-CoV-2 is a major cause of disease... read more

Provider Burnout and Fatigue During the COVID-19 Pandemic

Provider Burnout and Fatigue During the COVID-19 Pandemic

The novel Coronavirus Disease 2019 (COVID-19) pandemic has resulted in an overall surge in new cases of depression and anxiety and an exacerbation of existing mental health issues, with a particular emotional and physical... read more

COVID-19: Tube Exchange

COVID-19: Tube Exchange

Emergency physicians rarely are involved in tube exchanges; I can't remember the last time I had to do one. However, during the COVID19 surge, we found ourselves boarding intubated patients for days and even weeks as our... read more

Let’s Save Some Lives: A Doctor’s Journey Into the Pandemic

Let’s Save Some Lives: A Doctor’s Journey Into the Pandemic

There is no hope of outrunning the suffering that has settled into the hospital and the world around it, so Andrew Ibrahim laces up his blue waterproof sneakers and walks. In the time it has taken the daffodils to poke... read more

30 Days as a Medical Resident in New York City

30 Days as a Medical Resident in New York City

The coronavirus pandemic has reshaped everyone's lives. But for health-care workers, the impact of covid-19 is felt acutely, tragically, every day. To capture the lived reality of this, we asked Shaoli Chaudhuri, 29,... read more

What’s Working for COVID-19 Patients in the Epicenter

Our large tertiary care ED in Queens, NY, usually sees more than 100,000 adults a year. As we write this, we have 850 COVID-19-likely or -positive patients (several hundred above our bed capacity just one month ago), more... read more

The Fight Against COVID-19 Threatens to Cause Collateral Health Damage

The Fight Against COVID-19 Threatens to Cause Collateral Health Damage

The pandemic is no excuse to abandon chronic disease management and prevention. By one estimate 70,000 Americans will die in the first wave of the COVID-19 pandemic. This is a shocking number, of course, but it is far fewer... read more

On the Front Lines in Fight Against COVID-19

On the Front Lines in Fight Against COVID-19

As a worldwide pandemic washes over the St. Louis region, the Washington University Medical Campus is eerily quiet. Most visitors, students, staff and research faculty are no longer on campus. Limited patients come to its... read more

COVID-19 Patients with Respiratory Failure: What Can We Learn From Aviation Medicine?

COVID-19 Patients with Respiratory Failure: What Can We Learn From Aviation Medicine?

Patients with COVID-19 may present to hospitals and emergency medical services with an atypical form of acute respiratory distress syndrome (ARDS). Although anecdotal, a common clinical pattern has emerged, with a remarkable... read more

COVID-19: Two More Trials Just Published on Remdesivir

COVID-19: Two More Trials Just Published on Remdesivir

Currently, there are no approved medications for the treatment of COVID-19, but, there are many investigational agents that have shown antiviral activity against SARS-CoV-2 in vitro. Unfortunately in vitro studies do... read more

Pandemic Science Out of Control

Pandemic Science Out of Control

A toxic legacy of poor-quality research, media hype, lax regulatory oversight, and vicious partisanship has come home to roost in the search for effective treatments for COVID-19. The rush to offer unproven treatments... read more

Nationwide System to Centralize Decisions Around ECMO Use for Severe COVID-19 Pneumonia in Japan

Nationwide System to Centralize Decisions Around ECMO Use for Severe COVID-19 Pneumonia in Japan

The novel coronavirus disease 2019 (COVID-19) is spreading in Japan. The number of patients who need extracorporeal membrane oxygenation (ECMO) is expected to increase; however, the clinical characteristics of the patients... read more

POCUS for COVID-19

POCUS for COVID-19

This session peaked with 308 international participants logged on but many were watching in groups so likely to have been lots more tuned in! No longer Cinderella's ugly sister compared to Echo, lung ultrasound (LUS) is clearly... read more