COVID-19: Critical Care and Airway Management Issues

COVID-19: Critical Care and Airway Management Issues

Among patients hospitalized with coronavirus disease 2019 (COVID-19), up to one-quarter require intensive care unit (ICU) admission. Profound hypoxemic respiratory failure from acute respiratory distress syndrome (ARDS)... read more

Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections

Virus-Induced Changes of the Respiratory Tract Environment Promote Secondary Infections

Secondary bacterial infections enhance the disease burden of influenza infections substantially. Streptococcus pneumoniae (the pneumococcus) plays a major role in the synergism between bacterial and viral pathogens, which... read more

ICU-specific Virtual Reality for Psychological Recovery After ICU COVID-19 Treatment

ICU-specific Virtual Reality for Psychological Recovery After ICU COVID-19 Treatment

A substantial number of ICU survivors are expected due to the SARS-CoV-2 outbreak, who are at risk for psychological impairments, such as post-traumatic stress disorder (PTSD), anxiety, and depression. We designed a COVID-19... read more

Prone Position in Intubated, Mechanically Ventilated COVID-19 Patients

Prone Position in Intubated, Mechanically Ventilated COVID-19 Patients

During the COVID-19 pandemic, prone position has been widely adopted to treat mechanically ventilated patients with respiratory failure. The majority of patients improved their oxygenation during prone position, most likely... read more

Effects of Ventilatory Rescue Therapies on the Cerebral Oxygenation of COVID-19 Patients

Effects of Ventilatory Rescue Therapies on the Cerebral Oxygenation of COVID-19 Patients

A new study by Masimo published in Critical Care evaluated the impact of a variety of rescue therapies on the systemic and cerebral oxygenation of mechanically ventilated COVID-19 patients suffering from acute respiratory... read more

Effect of intubation timing on clinical outcomes of critically ill patients with COVID-19

Effect of intubation timing on clinical outcomes of critically ill patients with COVID-19

The synthesized evidence suggests that timing of intubation may have no effect on mortality and morbidity of critically ill patients with COVID-19. These results might justify a wait-and-see approach, which may lead to fewer... read more

Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?

Could Physical Therapy Interventions Be Adopted in the Management of Critically Ill Patients with COVID-19?

As part of COVID-19 consequences, it has been estimated that 5% of patients affected by this disease will require admission to the intensive care unit (ICU), and physical therapy techniques have been implemented in patients... read more

People with long-COVID at high risk of ongoing mental health issues

People with long-COVID at high risk of ongoing mental health issues

People living with long-COVID are at significant risk of experiencing depression and post-traumatic stress disorder (PTSD), according to research published in the European Respiratory Journal. The research is one of the... read more

Drug Treatments for COVID-19

Drug Treatments for COVID-19

Corticosteroids and interleukin-6 inhibitors probably confer important benefits in patients with severe covid-19. Janus kinase inhibitors appear to have promising benefits, but certainty is low. Azithromycin, hydroxychloroquine,... read more

On Cytokines, Fluvoxamine and COVID-19

On Cytokines, Fluvoxamine and COVID-19

Early in the COVID-19 pandemic, the role of ‘cytokine storm’ in patients with severe course was raised. Indeed, this triggered multiple investigations centred around calming excessive inflammation with pharmacotherapies... read more

Practice Recommendations on Neuraxial Anesthesia and Peripheral Nerve Blocks during the COVID-19 Pandemic

Practice Recommendations on Neuraxial Anesthesia and Peripheral Nerve Blocks during the COVID-19 Pandemic

General anesthesia (GA) with airway intervention leads to aerosol generation, which exposes the health care team to risk of transmission of COVID-19 both during intubation and extubation. The odds of transmission of acute... read more

COVID-19 vaccines effective for pregnant women, likely protect their babies too

COVID-19 vaccines effective for pregnant women, likely protect their babies too

COVID-19 mRNA vaccines are extremely effective at protecting pregnant and lactating women against the virus, and likely provide protection for their babies as well, according to a study published March 25 in the American... read more

Vaccine-Induced Prothrombotic Immune Thrombocytopenia After AstraZeneca COVID-19 Vaccination

Vaccine-Induced Prothrombotic Immune Thrombocytopenia After AstraZeneca COVID-19 Vaccination

The United Kingdom, European Union, and Scandinavian countries have reported that the AstraZeneca COVID-19 vaccine appears to be associated with rare cases of serious blood clots, including blood clots in the brain. These... read more

NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure

NeuroRx Announced Completion of Data Analysis for COVID-19 Treatment Respiratory Failure

NeuroRx, Inc. announced completion of top line data analysis of the 60-day results in its phase 2b/3 clinical trial, conducted under FDA Fast Track Designation, of ZYESAMI™ (aviptadil acetate) for the treatment of critically-ill... read more