Plasma Proteome Temporal Changes Associated with Sepsis Mortality

Our proteomics approach revealed significant associations between changes in the plasma proteome within the first days of sepsis and mortality as well as disease severity. We identified and characterised the underlying... read more

Mini Bronchoalveolar Lavage vs. Endo-Tracheal Aspirate in Diagnosing Bacterial Pneumonia in ICU

This study supports the use of endotracheal aspirate (ETA) as a cost-effective and efficient alternative to mBAL for the diagnosis of pneumonia in intubated ICU patients, particularly in settings where resources are limited.... read more

Sepsis: Clinical Diagnosis and Treatment

Sometimes our body's reaction to infection can result in damage to internal tissues and organs. Such a condition is referred to as sepsis. Some of the symptoms of sepsis are high fever, increased heart and breathing rate,... read more

Sepsis: Clinical Diagnosis and Treatment

The Infectious Disease Diagnosis: A Case Approach

This text uses cases to illustrate differential diagnoses of various infectious diseases. Unlike any other book on the market, this book is specifically designed for ease of use and can cater to a variety of medical professionals... read more

The Infectious Disease Diagnosis: A Case Approach

Outcomes of Older Adults With Sepsis at Admission to an ICU

Our study suggests that treating older adults with therapies recommended by the Surviving Sepsis Campaign may improve outcomes in this age group, although mortality remains high for older adults with sepsis. In addition,... read more

ARF Caused by Penicillium Marneffei Infection After Kidney Transplantation

Penicillium Marneffei (PM) infections often present with nonspecific clinical manifestations, and severe respiratory failure (ARF) after infection is particularly uncommon. This case report a patient who developed severe... read more

Septic Shock in the Prehospital Setting

Septic shock (SS) is a potential life-threatening condition in which an early identification and immediate therapy stand out as the main cornerstones to improve survival chance; in this context, emergency medical services... read more

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

The hemodynamic evaluation of patients with acute circulatory failure and respiratory failure has in the past usually been performed using invasive procedures but in recent years less invasive monitoring devices have been... read more

Hemodynamic Monitoring Using Echocardiography in the Critically Ill

Invasive Fungal Infections in Non-neutropenic Patients

Critically ill patients, particularly those with features of immunosuppression, are susceptible to invasive fungal infections (IFI), which pose significant diagnostic and therapeutic challenges. Candida and Aspergillus,... read more

Pulmonary Hypertension: Controversial and Emerging Topics

This book is a clinical guide to controversial and emerging topics in pulmonary hypertension. There are multiple challenges and unanswered questions encountered by clinicians that evaluate, diagnose and treat patients with... read more

Pulmonary Hypertension: Controversial and Emerging Topics

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19's impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic... read more

COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management

ICU Manual

This practical guide provides a multidisciplinary, clinically oriented approach to the management of patients in intensive care. The book discusses the complete range of specialties, including cardiology, pulmonology,... read more

ICU Manual

Disease Progression Associated Cytokines in COVID-19 Patients with Deteriorating and Recovering Health Conditions

Understanding the immune response to COVID-19 is challenging due to its high variability among individuals. To identify differentially expressed cytokines between the deteriorating and recovering phases, we analyzed the Electronic... read more

Association Between Comorbid COPD and Prognosis of Patients Admitted to ICU for Non-COPD Reasons

Comorbid COPD increased the risk of 28-day mortality among patients admitted to the ICU for non-COPD reasons, especially for those admitted to the cardiac surgery recovery unit. A retrospective cohort study was performed... read more

Risk Factors for Traumatic Intracranial Hemorrhage in Mild TBI Patients

The findings from this study provide additional context to risk factors currently in use as components in guidelines for the management of mild traumatic brain injury (mTBI) in the ED setting, contrasting high risk predictors... read more