Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients

Antibody responses are important in the control of viral respiratory infection in the human host. What is not clear for SARS-CoV-2 is how rapidly this response occurs, or when antibodies with protective capability evolve.... read more

Temporal development and neutralising potential of antibodies against SARS-CoV-2 in hospitalised COVID-19 patients

Barriers to reporting guideline adherence in POCUS research

Although investigators and editors recognise the importance of completely reported research, reporting quality is still a core issue for point-of-care ultrasound (POCUS) research. The shared opinion held by investigators... read more

Barriers to reporting guideline adherence in POCUS research

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

Urine foaming test (UFT) is useful, particularly in predicting the clinical severity of COVID-19. The UFT could be recommended as a point of care test, rapid and non-invasive method in the diagnosis and follow-up of COVID-19. A... read more

COVID-19 Diagnosis and Prognosis Using the Urine Foaming Test

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

A 62-year-old male with a history of hypertension, congestive heart failure, type II diabetes mellitus, and tobacco use presents to the emergency department (ED) with severe left lower leg pain that started six hours ago.... read more

Systematic Approach to the Peripheral Vascular Exam: Pearls & Pitfalls

Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine

In this review, we provide an overview of the role of fatty acid-derived lipid mediators as endogenous regulators of the inflammatory, anti-inflammatory and pro-resolving response and future directions for use of clinical... read more

Lipid Mediators in Critically Ill Patients: A Step Towards Precision Medicine

Smell test may help spot COVID-19 cases

A scratch-and-sniff screening tool that identifies impaired sense of smell, a common symptom of COVID-19, could help quickly pinpoint cases. Researchers from the University of Colorado in Boulder studied a smell test called... read more

Smell test may help spot COVID-19 cases

An Online Tool to Simulate the Effect of Pooled Testing for COVID-19

This diagnostic study describes an online tool created with actual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus copy number data to help policy makers understand how pooled testing compares with single-sample... read more

An Online Tool to Simulate the Effect of Pooled Testing for COVID-19

Cancer Biomarker Measurement using a Smartphone

Canadian researchers create technology that reads cancer biomarker like a blood-sugar monitor. Researchers at the Canadian McMaster and Brock universities have created the prototype for a smartphone device to measure a biomarker... read more

Cancer Biomarker Measurement using a Smartphone

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually... read more

Critical Care Medicine: Principles of Diagnosis and Management in the Adult

The Royal Marsden Manual of Clinical Nursing Procedures

Now in its tenth edition, The Royal Marsden Manual of Clinical Nursing Procedures has been the definitive, market-leading guide to clinical nursing skills for over three decades. This internationally best-selling title sets... read more

The Royal Marsden Manual of Clinical Nursing Procedures

Wallach’s Interpretation of Diagnostic Tests

An excellent resource for appropriate test ordering and interpretation, Wallach's Interpretation of Diagnostic Tests, 11th Edition, helps you save time, avoid errors, and arrive at an accurate diagnosis. Organized into two... read more

Wallach’s Interpretation of Diagnostic Tests

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

Appropriate clinical decision-making in the initial evaluation and management of trauma patients in the emergency department is critical to optimize patient outcomes. This supplement provides evidence-based recommendations... read more

Limiting Radiation in Trauma Imaging & Trauma Resuscitation

When Should I Worry About a PE in a Patient with COVID-19

PE diagnosis in COVID-19 patients is challenging. Many of the features of PE, such as shortness of breath and hypoxemia, are very common in patients with COVID-19, even in the absence of PE. Further, the diagnostic tests... read more

30% of COVID-19 Patients Had No Symptoms of Fever, Cough, or Shortness of Breath

The findings of this cohort study suggest that screening based on conventional COVID-19 symptoms or corresponding examination findings of febrile respiratory illness may not possess the necessary sensitivity for early diagnostic... read more

30% of COVID-19 Patients Had No Symptoms of Fever, Cough, or Shortness of Breath

Review of Viral Testing and Antibody/Serology Testing for COVID-19 for the Intensivist

The severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) (coronavirus disease 2019 [COVID-19]) pandemic has led to the rapid development of many diagnostic tests. The initial focus of these tests was on molecular... read more

Review of Viral Testing and Antibody/Serology Testing for COVID-19 for the Intensivist

Infectious Meningitis and Encephalitis in ICU

Infectious meningitis and encephalitis are a major concern in ICU since they are associated with high mortality and permanent neurological injury. About 3% of central nervous system infections will be admitted in the ICU. Three... read more

Infectious Meningitis and Encephalitis in ICU

Early Prediction of ICU-Acquired Weakness

The previously developed prediction model for ICU-AW showed poor performance in a new independent multicenter validation cohort. Model updating methods improved calibration but not discrimination. The newly derived prediction... read more

Early Prediction of ICU-Acquired Weakness

Clinical Characteristics of Patients With COVID-19 Receiving Emergency Medical Services

This cohort study of 124 patients with COVID-19 revealed that most patients with COVID-19 presenting to emergency medical services were older and had multiple chronic health conditions. Initial concern, symptoms, and examination... read more

Clinical Characteristics of Patients With COVID-19 Receiving Emergency Medical Services