Methylnaltrexone for Treatment of Opioid-induced Constipation in Critically Ill Patients

Methylnaltrexone for Treatment of Opioid-induced Constipation in Critically Ill Patients

No evidence to support the addition of methylnaltrexone to regular laxatives for the treatment of opioid-induced constipation in critically ill patients; however, the confidence interval was wide and a clinically important... read more

Initial Therapy Affects Duration of Diarrhoea in Critically Ill Patients with Clostridioides Difficile Infection

Initial Therapy Affects Duration of Diarrhoea in Critically Ill Patients with Clostridioides Difficile Infection

Clostridioides Difficile Infection (CDI) further harms critically ill patients by increasing 28-day mortality and in case of prolonged diarrhoea the length of their hospital stay. Appropriate therapy should be initiated... read more