Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Therapeutic Interchange of Clevidipine For Sodium Nitroprusside in Cardiac Surgery

Sodium nitroprusside (SNP) has been used clinically for decades for the treatment of hypertension associated with cardiac surgery.... read more

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Metformin and Aspirin Potential Key in Treating Inflammatory Diseases

Ingredient in aspirin combined with popular diabetes drug can turn off faulty protein that plays a key role in inflammatory diseases, such as rheumatoid arthritis. ... read more

Drug does not significantly reduce duration of mechanical ventilation for COPD patients

Drug does not significantly reduce duration of mechanical ventilation for COPD patients

Among mechanically ventilated patients with COPD, administration of the respiratory stimulant acetazolamide did not significantly reduce the duration of invasive mechanical ventilation.... read more

Examining When to Provide Pain Management for Patients

Examining When to Provide Pain Management for Patients

Sometimes a lack of pain medication is the patient's best form of treatment. Eradicating pain has been a focus of medicine throughout history, from the early use of cocaine to the current use of fentanyl. As a prehospital... read more

Acetaminophen in the ICU: Mixed Findings

Acetaminophen in the ICU: Mixed Findings

Does having a fever help fight infection? Patients who got acetaminophen to relieve fever while in intensive care units did about as well as patients who got a placebo when it came to mortality. But in a puzzling finding,... read more

Prescribed Morphine Milligram Equivalents of Opioids by County

Prescribed Morphine Milligram Equivalents of Opioids by County

Despite reductions in opioid prescribing in some parts of the USA, the amount of opioids prescribed remains high relative to 1999 levels and varies substantially at the county-level. Given associations between opioid prescribing,... read more

Update: Implementation of Antibiotic Stewardship Core Elements

Update: Implementation of Antibiotic Stewardship Core Elements

This document provides guidance on practical strategies to implement antibiotic stewardship programs in small and critical access hospitals. It was developed as a collaboration between The Centers for Disease Control and... read more

Ketamine: A Drug at War with Itself

Ketamine: A Drug at War with Itself

KETAMINE has always been the odd one out. Like an eccentric uncle who always turns up at the holiday season with a new partner, ketamine has never really comfortably fitted in to simple classifications of anesthetic drugs.... read more

Four ways to reduce dangerous medical errors at your hospital

Four ways to reduce dangerous medical errors at your hospital

It's human nature, everyone makes mistakes. But the consequences of those mistakes can range wildly not only according to their severity, but also depending on who commits them. When a marketer makes a typo on a press release,... read more

Acetaminophen, Among Other Medications, Triggers Drug-Induced Liver Injury

Acetaminophen, Among Other Medications, Triggers Drug-Induced Liver Injury

More than 1,000 medications, with acetaminophen being the most common, have been associated with drug-induced liver injury (DILI). Diagnosis can be challenging due to the multitude of contributing factors, and timely recognition... read more

Sepsis Algorithm a Deadly Marker

Sepsis Algorithm a Deadly Marker

An attempt by a Phoenix, AZ, hospital to develop a marker for deadly sepsis instead found that the algorithm identified patients at an increased risk of dying. Increasingly, algorithms govern daily life, playing an important... read more

Characterizing Hydrogels for use in drug delivery systems

Characterizing Hydrogels for use in drug delivery systems

The delivery of drugs to a precise location at the desired concentration without causing toxic effects to the rest of the body has been a challenge to biomedical science for many years. Although several approaches have been... read more

Alpha blockers more effective for large kidney stones

Alpha blockers more effective for large kidney stones

Researchers report a 57 percent higher risk of stone passage for larger stones with an alpha blocker, but no benefit for smaller stones. Location did not make a difference, nor did type of alpha blocker used.... read more

Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

Drugs Don’t Cut Trastuzumab-Tied Left Ventricular Remodeling

The researchers found that the drugs were well tolerated, with no serious adverse events reported. The indexed left ventricular end diastolic volume increased in patients treated with perindopril, bisoprolol, and placebo... read more