FDA Approves sNDA for Label Changes to ADASUVE

FDA Approves sNDA for Label Changes to ADASUVE

The FDA has approved the supplemental New Drug Application for label changes to ADASUVE (loxapine) inhalation powder. ADASUVE is the first orally inhaled medication for the acute treatment of agitation associated with bipolar... read more

Impaired recycling of mitochondria in autism?

Impaired recycling of mitochondria in autism?

The new study shows that autophagy is defective in TSC. The scientists further showed that two existing classes of drugs counter the defect: the epilepsy drug carbamazepine, and drugs known as mTOR inhibitors.... read more

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA Provides Guidance on Drug-Drug Interactions With Statins and CVD Medications

AHA has released a new scientific statement for managing clinically significant drug-drug interactions in patients who are prescribed statins and other agents used in the treatment of cardiovascular disease.... read more

Newer blood thinning drugs safer for reducing atrial fibrillation

Newer blood thinning drugs safer for reducing atrial fibrillation

Although warfarin has been used for nearly 60 years, researchers say newer blood thinners are a better option for lowering stroke risk among atrial fibrillation patients because they work for a shorter time with fewer side... read more

Bifunctional drug could treat tumors resistant to current mTOR inhibitors

Bifunctional drug could treat tumors resistant to current mTOR inhibitors

The first known bifunctional inhibitor for the mechanistic target of rapamycin (mTOR) protein was developed to overcome current known mechanisms of tumor resistance to mTOR inhibitors.... read more

Scientists film bacteria's maneuvers as they become impervious to drugs

Scientists film bacteria's maneuvers as they become impervious to drugs

In a creative stroke inspired by Hollywood wizardry, scientists from Harvard Medical School and Technion-Israel Institute of Technology have designed a simple way to observe how bacteria move as they become impervious to... read more

Shortages Of Essential Emergency Care Drugs Increase, Study Finds

Shortages Of Essential Emergency Care Drugs Increase, Study Finds

The problems persist even after Congress in 2012 gave the FDA enhanced powers to respond when drug levels are low. At some hospitals, posters on the wall in the emergency department list the drugs that are in short supply... read more

Non-addictive Painkiller Shows Promise in Animal Trials

Non-addictive Painkiller Shows Promise in Animal Trials

Preliminary research in monkeys suggests that a new medication might be able to provide pain relief similar to opioid drugs such as OxyContin, but without the same potential for addiction or serious side effects.... read more