Tag: ECMO
Platelet Function During ECMO in Adult Patients
Employing impedance aggregometry and flow cytometry, we found both impaired platelet aggregation and decreased platelet activation on day 1 of Extracorporeal Membrane Oxygenation (ECMO) support compared with healthy controls.... read more
Implementation of a Standardized Transfusion Protocol for Cardiac Patients Treated With Venoarterial ECMO Is Associated With Decreased Blood Component Utilization and May Improve Clinical Outcome
The data indicate that implementation of a standardized transfusion protocol, using more restrictive transfusion indications in cardiac ECMO patients, was associated with reduced blood product utilization, decreased complications,... read more
Mechanical Ventilation Management during ECMO for ARDS
Ultra-protective lung ventilation on ECMO was largely adopted across medium to high case-volume ECMO centers. In contrast with previous observations, mechanical ventilation settings during ECMO did not impact patients' prognosis... read more
Mechanical Circulatory Support Devices in Cardiogenic Shock and Acute Heart Failure
Randomized, controlled trials are utterly needed to guide treatment with mechanical circulatory support for patients with cardiogenic shock. Importantly, such trials should focus patient selection criteria. In recent years,... read more
Lung Recruitability in Severe ARDS Requiring ECMO
Significant variability in potential for lung recruitment in patients with severe acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO). 47 adults with severe ARDS requiring ECMO... read more
Emergency Department Resuscitation of the Critically Ill
A crash course in Critical Care! Stabilize, treat, and save your sickest patients in the ed or the field – with ACEP's ultimate resuscitation guide. packed with succinct evidence-based chapters written by the nation's foremost... read more
Sedation Practices of Neonates Receiving ECMO
Neonatal sedation practices during extracorporeal membrane oxygenation (ECMO) are not well described and no universal guidelines exist. Current literature describes types of medications used in adult and pediatric ECMO... read more
Risk Factors Associated with 30-day Mortality for Out-of-Center ECMO Support
Out-of-hospital extracorporeal membrane oxygenation (ECMO) implantation and ECMO transport have become a growing field useful for emergent treatment of heart or lung failure with increasing number of centers launching such... read more
Interhospital Transport on Extracorporeal Membrane Oxygenation of Neonates
In recent years the number of extracorporeal membrane oxygenation (ECMO) cases in neonates has been relatively constant. Future expansion lays in new indications for treatment. Regionalization to high-volume ECMO centers... read more
Hemodynamic Monitoring – The Why, When, Which and What
Although the need to properly assess and monitor the hemodynamic status of a critically ill patient appears self-evident, the plethora of information in the published literature over the past two decades has resulted in complexity... read more
ECMO and Bloodstream Infection in Congenital Diaphragmatic Hernia
The objective of this review is to characterize the risk of bloodstream infection (BSI) and urinary tract infection (UTI) and describe antibiotic use in infants with congenital diaphragmatic hernia (CDH) requiring extracorporeal... read more
How Best to Set the Ventilator on Extracorporeal Membrane Lung Oxygenation
Mechanical ventilation and extracorporeal support are marginally integrated. The best environment for lung healing – complete lung collapse or protective ventilation strategy or fully open and immobile lung (all three conditions... read more
Time-Course of Clinical Physiologic Variables in ARDS Patients Undergoing ECMO
In patients undergoing extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS), it is unknown which clinical physiologic variables should be monitored to follow the evolution of lung injury... read more
Hemodynamic Monitoring in the ECMO Patient
Hemodynamic monitoring in extracorporeal membrane oxygenation (ECMO) patients requires familiarity with the underlying pathophysiology and circulatory mechanics of extracorporeal flow. This review discusses the various monitoring... read more
Prevalence and outcome of heparin-induced thrombocytopenia diagnosed under veno-arterial extracorporeal membrane oxygenation
Prevalence of HIT among patients under VA‑ECMO is extremely low at 0.36% with an associated mortality rate of 33.3%, which appears to be in the same range as that observed in patients treated with VA‑ECMO without HIT.... read more
Identifying At-Risk Patients for Sub-optimal Beta-lactam Exposure in Critically Ill Patients with Severe Infections
Conventional beta-lactam dosing is flawed in critically ill patients. Useful tools such as the MeroRisk Calculator need to be comprehensively evaluated clinically, and if successful should be added into clinical practice... read more
Neuromuscular Blockade for ARDS Was No Help, In Supine Patients
Continuous neuromuscular blockade for severe ARDS became common practice after the ACURASYS trial showed it reduced mortality by an absolute 9%. A larger trial, ROSE, now finds no benefit of the therapy over usual care, but... read more