An Interview With an Italian Intensivist on the COVID Experience in Italy

An Interview With an Italian Intensivist on the COVID Experience in Italy

The current COVID-19 crisis has a huge human impact. Clearly cardiovascular issues have a central role in management and, unfortunately, in adverse outcomes. We are continually struggling to understand risks and management... read more

ARDS Diagnosis May Be Underrecognized

ARDS Diagnosis May Be Underrecognized

The February 27, 2020 Department of Internal Medicine Medical Grand Rounds "Acute Respiratory Distress Syndrome (ARDS),” was presented by Marc Moss, MD, Roger S. Mitchell Professor of Medicine; head, Division of Pulmonary... read more

ECMO Support in Coronavirus Disease 2019 (COVID-19)

ECMO Support in Coronavirus Disease 2019 (COVID-19)

Extracorporeal membrane oxygenation (ECMO) use has been increasing in severe respiratory and/or cardiac failure despite implementation of conventional care. This technology has been proven valuable in treating viral pneumonia... read more

Multi-Modal Characterization of the Coagulopathy Associated With ECMO

Multi-Modal Characterization of the Coagulopathy Associated With ECMO

The extracorporeal membrane oxygenation(ECMO)-associated coagulopathy is a multifactorial and quickly developing syndrome. It is characterized by individual changes of coagulation parameters and platelets and is aggravated... read more

Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO

Prone Positioning Monitored by Electrical Impedance Tomography in Patients with Severe ARDS on VV-ECMO

Prone positioning (PP) during veno-venous ECMO is feasible, but its physiological effects have never been thoroughly evaluated. Our objectives were to describe, through electrical impedance tomography (EIT), the impact of... read more

Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU

Impact of Levosimendan on Weaning from Peripheral VA-ECMO in ICU

This study suggests that levosimendan might be associated with a beneficial effect on venoarterial extracorporeal membrane oxygenation (VA-ECMO) weaning in ICU patients. The difference in mortality among propensity-matched... read more

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation Evolution in Patients on VA-ECMO for Refractory Cardiogenic Shock

Microcirculation is severely impaired in patients with refractory cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation (VA-ECMO). Inability to rapidly restore microcirculation during the first... read more

Cannula and Circuit Management in Peripheral ECMO

Cannula and Circuit Management in Peripheral ECMO

Variable practices regarding extracorporeal membrane oxygenation (ECMO) line management exist worldwide based on recommendations lacking specific ECMO content and context. This survey identified evidence gaps regarding... read more

Defining Benefit Threshold for ECMO in Children with Sepsis

Defining Benefit Threshold for ECMO in Children with Sepsis

This binational study demonstrates that a rapidly available sepsis mortality prediction model can define thresholds for survival benefit in children with septic shock considered for ECMO. Survival on ECMO was associated... read more

Outcomes of VV ECMO When Stratified by Age

Outcomes of VV ECMO When Stratified by Age

The purpose of this study was to evaluate survival to hospital discharge for patients on venovenous extracorporeal membrane oxygenation (VV ECMO) when stratified by age. We performed a retrospective study at single, academic,... read more

Low-flow Assessment of Current ECMO/ECCO2R Rotary Blood Pumps and the Potential Effect on Hemocompatibility

Low-flow Assessment of Current ECMO/ECCO2R Rotary Blood Pumps and the Potential Effect on Hemocompatibility

The role of blood pumps in contributing to adverse effects at the lower blood flow rates used during ECCO2R is shown here to be significant. Current rotary blood pumps should be used with caution if operated at blood... read more

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

Using Additional Pressure Control Lines When Connecting a Continuous RRT Device to an ECMO Circuit

The present study suggests that the use of additional tubing can be considered a simple and safe method for pressure control and improvement of filter survival when connecting a continuous renal replacement therapy (CRRT)... read more

Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Venoarterial Extracorporeal Membrane Oxygenation in Cardiogenic Shock

Temporary circulatory support (TCS) have become the cornerstone of the management of patients with cardiogenic shock, although the evidence supporting their efficacy is limited. VA-ECMO is considered the first-line option,... read more

ECMO in Out-of-Hospital Cardiac Arrest

ECMO in Out-of-Hospital Cardiac Arrest

In a population-based registry, 4% of out-of-hospital cardiac arrests (OHCA) were treated with extracorporeal-CPR, which was not associated with increased hospital survival. Early extracorporeal membrane oxygenation (ECMO)... read more