Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

Guidelines for the Content of Statistical Analysis Plans in Clinical Trials

While guidance on statistical principles for clinical trials exists, there is an absence of guidance covering the required content of statistical analysis plans (SAPs) to support transparency and reproducibility. Recommendations... read more

Dietitians in Critical Care

Dietitians in Critical Care

Patients in the critical care setting are at risk of malnutrition. The provision of nutrition support (enteral or parenteral) to critically ill patients is vital, but achieving the optimum quantity and balance is a contentious... read more

Four in Five U.S. Physicians Have Been Affected by Cyberattacks

Four in Five U.S. Physicians Have Been Affected by Cyberattacks

More than four in five U.S. physicians (83 percent) have experienced some form of a cybersecurity attack, according to new research released by Accenture and the American Medical Association (AMA). This, along with additional... read more

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency – Part I

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency – Part I

Evidence-based recommendations for the use of corticosteroids in critically ill patients with sepsis and septic shock, acute respiratory distress syndrome, and major trauma have been developed by a multispecialty task force.... read more

Recommendations for a Standardized Pulmonary Function Report

Recommendations for a Standardized Pulmonary Function Report

The American Thoracic Society committee on Proficiency Standards for Pulmonary Function Laboratories has recognized the need for a standardized reporting format for pulmonary function tests. Although prior documents have... read more

Eye Protection in Anaesthesia and Intensive Care

Eye Protection in Anaesthesia and Intensive Care

New guidelines on prevention of eye injuries during anaesthesia and intensive care have been developed by the French Society for Anaesthesia and Intensive Care Medicine (SFAR), together with the French Ophthalmology Society... read more

New Guidance for Medication Safety in the ICU

New Guidance for Medication Safety in the ICU

Critically ill patients are a population at high risk for more frequent and more severe medication-related events. Critically ill patients receive twice the number of medications that non-critically ill, hospitalized patients... read more

Post Resuscitation Management of Cardiac Arrest Patients in the Critical Care Environment

Post Resuscitation Management of Cardiac Arrest Patients in the Critical Care Environment

There is a clear relationship between evidence-based post resuscitation care and survival and functional status at hospital discharge. The Australian Resuscitation Council (ARC) recommends protocol driven care to enhance... read more

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Increase in antibiotic-resistant bacteria hinders treatment of kidney infections

Researchers use hospital emergency room data from around the country to document emergence of E. coli strain that fights medication. They recommend development of new antibiotics and treatment guidelines.... read more

iSepsis – A 30ml/kg Bolus: Yes or No -The Results

iSepsis – A 30ml/kg Bolus: Yes or No -The Results

The results of both surveys are not surprising. This recommendation has never been prospectively tested in a large RCT and has little supporting evidence. Imagine the American Heart Association (AHA) or the American Diabetes... read more

50 Years of Research in ARDS

50 Years of Research in ARDS

Mechanical ventilation (MV) is critical in the management of many patients with the acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate... read more

Promoting High-Value Practice by Reducing Unnecessary Transfusions With a Patient Blood Management Program

Promoting High-Value Practice by Reducing Unnecessary Transfusions With a Patient Blood Management Program

Although blood transfusion is a lifesaving therapy for some patients, transfusion has been named 1 of the top 5 overused procedures in US hospitals. As unnecessary transfusions only increase risk and cost without providing... read more

Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation

Early Exercise in Critically Ill Youth and Children, a Preliminary Evaluation

Early mobilization is safe and feasible in the PICU. In-bed cycling may facilitate greater duration and intensity of mobilization, in critically ill children. A full-scale randomized controlled trial is warranted to evaluate... read more

The New Blood Pressure Guidelines

The New Blood Pressure Guidelines

The last time a major updates to the identification, classification and treatment of high blood pressure (hypertension) was 2003. Finally, the long anticipated updated comprehensive guidelines were released earlier this month... read more

Better Living Quality for Intensive Care

Better Living Quality for Intensive Care

Aiming to bring "Better Living in Intensive Care" for both patients and caregivers, the French Intensive Care Society issued guidelines to promote quality of life for ICU. As the largest premier reference and teaching hospital... read more

Is Intravenous Administration of Iodixanol Associated with Increased Risk of AKI, Dialysis, or Mortality?

Is Intravenous Administration of Iodixanol Associated with Increased Risk of AKI, Dialysis, or Mortality?

Among patients at the highest perceived risk of post-contrast Acute Kidney Injury (AKI), intravenous administration of iodixanol for contrast material enhanced CT was not an independent risk factor for AKI, dialysis, or... read more

Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs

Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs

Central line–associated bloodstream infection (CLABSI) and catheter-associated urinary tract infection (CAUTI) are costly and morbid. Despite evidence-based guidelines, Some intensive care units (ICUs) continue to have... read more