Metabolomic Diferences: COVID-19 vs. H1N1 Influenza in ARDS

Metabolomic Diferences: COVID-19 vs. H1N1 Influenza in ARDS

This study aimed to compare the specificity of the metabolic alterations induced by COVID-19 or Influenza A pneumonia (IAP) in acute respiratory distress syndrome (ARDS). Our findings support the concept that ARDS is associated... read more

Lung Histopathology in COVID-19 as Compared to SARS and H1N1 Influenza

Lung Histopathology in COVID-19 as Compared to SARS and H1N1 Influenza

Diffuse alveolar damage (DAD) was reported in 88% of patients with COVID-19. This is similar to both H1N1 (90%) and SARS (98%). Pulmonary microthrombi was reported in 57% of patients with COVID-19. This was similar to... read more

Severe Influenza in Critically Ill Patients

Severe Influenza in Critically Ill Patients

The present review summarizes current knowledge on pathogenesis and clinical manifestations of severe influenza. Immunological dysfunction during viral infection correlates with severity and mortality among ICU patients.... read more

The Efficacy of ECMO for Severe ARDS

The Efficacy of ECMO for Severe ARDS

The H1N1 epidemic demonstrated that extracorporeal membrane oxygenation (ECMO) use in the most critically ill patients with acute respiratory distress syndrome (ARDS) resulted in a substantial decrease in mortality. The CESAR... read more

Early Oseltamivir Therapy Improves the Outcome in Critically Ill with Influenza

Early Oseltamivir Therapy Improves the Outcome in Critically Ill with Influenza

This real-life study emphasizes oseltamivir efficacy on in-hospital outcome when administrated within 2 days of the onset of symptoms. Even if physicians' awareness of the influenza disease has been undeniably enhanced... read more