Tag: hypoxemia
Management and Outcomes of ARDS Patients With and Without Comorbid Conditions
Half the patients with acute respiratory distress syndrome (ARDS) had major comorbidities, which were associated with severe ARDS, multiple organ dysfunction, and day‑28 mortality. These findings do not support the exclusion... read more
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Evaluating the Cost-Effectiveness of Proportional-Assist Ventilation Plus vs. Pressure Support Ventilation in the ICU in Two Countries
The published reductions in asynchrony and length of stay in the ICU with proportional assist ventilation (PAV ventilation by Medtronic) led to shorter time on ventilation, and reduced incidence of ventilator-associated pneumonia... read more
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The Answer My Friend is Blowin’ in your Nose – High Flow Nasal Oxygen
High flow nasal oxygen is a novel device that actively humidifies and heats air to make flows of up to 60 liters a minutes tolerable. These incredibly high flows are important, because in order to provide 100% fiO2 to patients... read more
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Resuscitation Sequence Intubation – Hypoxemia Kills
This blog post is the second part of a series of 3, on a recent lecture I was asked to give on Critical Care Updates: Resuscitation Sequence Intubation. This talk was mostly derived from a podcast by Scott Weingart (Twitter:... read more
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ECMO for Severe Middle East Respiratory Syndrome Coronavirus
Extracorporeal membrane oxygenation (ECMO) use, as a rescue therapy, was associated with lower mortality in MERS patients with refractory hypoxemia. The results of this, largest to date, support the use of ECMO as a rescue... read more
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Gas Exchange in ARDS
Acute respiratory distress syndrome (ARDS) is characterized by severe impairment of gas exchange. Hypoxemia is mainly due to intrapulmonary shunt, whereas increased alveolar dead space explains the alteration of CO2 clearance.... read more
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A multicenter, randomized trial of a checklist for endotracheal intubation of critically ill adults
The verbal performance of a written, pre-procedure checklist does not increase the lowest arterial oxygen saturation or lowest systolic blood pressure during endotracheal intubation of critically ill adults compared to usual... read more
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Oxygen Therapy in Suspected Acute Myocardial Infarction
Routine use of supplemental oxygen in patients with suspected myocardial infarction who did not have hypoxemia was not found to reduce 1-year all-cause mortality. A total of 6629 patients were enrolled. The median duration... read more
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Video vs direct laryngoscopy in the ICU: are we asking the right question?
Endotracheal intubation in the operating room (OR) and the ICU are different procedures, but this is not always recognized. The ICU patient should be evaluated as a physiologically difficult airway, in contrast to the traditional... read more
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Rocketamine vs. Keturonium for Rapid Sequence Intubation
Airway management is a detail-oriented sport. Minor nuances of patient positioning can be essential. Or gentle laryngeal manipulation. Apneic oxygenation can improve first-pass success. Placing the pulse oximeter on the... read more
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Comparison of Alveolar Recruitment Strategies for Preventing Postoperative Pulmonary Complications
This randomized clinical trial compares the effects of adding an intensive vs moderate alveolar recruitment strategy to protective ventilation on the number and severity of pulmonary complications following cardiac surgery.... read more
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Normal Saline as Resuscitation Fluid in Critically Ill
The study of Van Regenmortel et al. indirectly underscores growing equipoise in the expert medical community regarding the presumed harmful effects of NS compared with balanced crystalloids. Future studies, such as the ongoing... read more
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Guidelines for Neuromuscular Blockade in the Adult Critically Ill Patient
The Society of Critical Care Medicine recently released guidelines addressing sustained neuromuscular blockade in the adult critically ill patient.... read more
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