Saline vs. Balanced Crystalloid in Patients with Diabetic Ketoacidosis

Saline vs. Balanced Crystalloid in Patients with Diabetic Ketoacidosis

In patients with diabetic ketoacidosis (DKA), the use of saline may be associated with longer time to DKA resolution, higher post-resuscitation serum chloride levels, lower post-resuscitation serum bicarbonate levels, and... read more

Hyperchloremia Is Associated With AKI in Patients With Subarachnoid Hemorrhage

Hyperchloremia Is Associated With AKI in Patients With Subarachnoid Hemorrhage

Critically ill patients with subarachnoid hemorrhage show a strong association between hyperchloremia and acute kidney injury as well as acute kidney injury and mortality. Of 1,267 patients included in this cohort, 16.7%... read more

Serum Chloride Levels in Critical Illness – The Hidden Story

Serum Chloride Levels in Critical Illness – The Hidden Story

Chloride is the principal anion of the extracellular fluid and vital for both serum electroneutrality and acid-base homeostasis. The aim of this review is to investigate the relevance of dyschloremia in the critically... read more

Normal Saline as Resuscitation Fluid in Critically Ill

Normal Saline as Resuscitation Fluid in Critically Ill

The study of Van Regenmortel et al. indirectly underscores growing equipoise in the expert medical community regarding the presumed harmful effects of NS compared with balanced crystalloids. Future studies, such as the ongoing... read more