Prone Positioning of ARDS Patients

A prospective international observational prevalence study on prone positioning of ARDS patients: the APRONET (ARDS Prone Position Network) study. While prone positioning (PP) has been shown to improve patient survival in... read more

On Diagnosing Sepsis

Two years ago, a panel appointed by the Society of Critical Care Medicine and the European Society of Intensive Care Medicine, referred to as a consensus conference, proposed a new definition for sepsis and new diagnostic... read more

Animal-assisted Intervention in the ICU: A Tool for Humanization

The combination of an aging population and advances in critical care medicine is resulting in a growing number of survivors of critical illness. Survivors' descriptions of their stay in an intensive care unit (ICU) are frequently... read more

Trends of Incidence and Risk Factors of VAP in Elderly Patients Admitted to French ICUs

This study assesses trends and risk factors of ventilator-associated pneumonia (VAP) according to age, particularly in the elderly admitted to French ICUs between 2007 and 2014. Ventilator-associated pneumonia incidence is... read more

Distributions and Behavior of Vital Signs in Critically Ill Children by Admission Diagnosis

This is the first study reporting distributions of continuously measured physiologic variables and trends in their behavior according to admission diagnosis in critically ill children. Differences detected between and within... read more

Is Overall Mortality the Right Composite Endpoint in Clinical Trials of ARDS?

Most deaths in acute respiratory distress syndrome (ARDS) patients are not directly related to lung damage but to extrapulmonary multisystem organ failure. It would be challenging to prove that specific lung-directed therapies... read more

Persistence of Delirium after Cessation of Sedatives and Analgesics and Impact on Clinical Outcomes in Critically Ill Patients

As delirium is a common manifestation in critically ill patients and is associated with worse clinical outcomes, we sought to characterize the reversibility of delirium after discontinuation of sedation and to determine whether... read more

Music as Therapy in the ICU

Music has been shown to reduce respiratory, cardiac and blood pressure frequencies in response to the reduction of stress hormones. In a randomized clinical trial, it was shown to reduce anxiety and sedation doses/intervals... read more

Recovery After Critical Illness: Putting the Puzzle Together

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new... read more

The Effects of Antibiotic Cycling and Mixing on Antibiotic Resistance in ICU

Whether antibiotic rotation strategies reduce prevalence of antibiotic-resistant, Gram-negative bacteria in intensive care units (ICUs) has not been accurately established. We aimed to assess whether cycling of antibiotics... read more

Long-term Recovery Following Critical Illness in an Australian Cohort

Almost all data on 5-year outcomes for critical care survivors come from North America and Europe. The aim of this study was to investigate long-term mortality, physical function, psychological outcomes and health-related... read more

Adjuvant Therapies in Critical Care: Music Therapy

Emerging from the perioperative and oncology fields, music therapy (MT) and patient-directed music interventions (PDMI) have recently garnered interest in the area of critical care. The main goal of these music-based adjuvant... read more

Receiving a Letter of Condolence After Loss of a Loved One in the ICU

This study describes the benefits of receiving a letter of condolence; mainly, it humanizes the medical institution (feeling of support, confirmation of the role played by the relative, supplemental information). However,... read more

Cerebral Autoregulation in the Prediction of Delayed Cerebral Ischemia and Clinical Outcome in Poor-Grade Aneurysmal Subarachnoid Hemorrhage Patients

High initial pressure reactivity index, presumably reflecting early brain injury, but not oxygen reactivity index, was associated with delayed cerebral ischemia and worse clinical outcome in poor-grade subarachnoid hemorrhage... read more

Outcomes of Ethics Consultations in Adult ICUs

Our review identified outcome-based assessment as the predominant measure used to report effectiveness of clinical ethics consultation consultations. In particular, clinical ethics consultation decreased ICU length of stay... read more

The Utility of ICU Readmission as a Quality Indicator and the Effect of Selection

Intensive care readmission rates are used to signal quality, yet it is unclear whether they represent poor quality in the transition of care from the ICU to the ward, patient factors, or differences in survival of the initial... read more

Mastering Intensive Care – Making an Excellent Start to an Intensive Care Career

What are the biggest challenges when beginning as a fully-fledged intensive care clinician? How do you best use your senior colleagues when your experience bank is still small? What can you do to help achieve gender equity... read more

The Effect of a Quality Improvement Intervention on Perceived Sleep Quality and Cognition in the ICU

An ICU-wide quality improvement intervention to improve sleep and delirium is feasible and associated with significant improvements in perceived nighttime noise, incidence of delirium/coma, and daily delirium/coma-free status.... read more

Physician Genders and the Likelihood of ICU Admission in Hospital with Restricted ICU Bed Capacity

Despite the evidence that the patient gender is an important component in the intensive care unit (ICU) admission decision, the role of physician gender and the interaction between the two remain unclear. We demonstrated... read more

Effect of Emergency Department and ICU Occupancy on Admission Decisions and Outcomes for Critically Ill Patients

ICU admission decisions for critically ill emergency department patients are affected by medical ICU bed availability, though higher emergency department volume and other ICU occupancy did not play a role. Prolonged emergency... read more

Moral distress and its contribution to the development of burnout syndrome among critical care providers

Correlation between moral distress and burnout was assessed among all intensive care unit (ICU) and the step–down unit (SDU) providers (physicians, nurses, nurse technicians and respiratory therapists). Researchers reported... read more

Effect of Nocturnal Sound Reduction on the Incidence of Delirium in ICU Patients

The incidence of delirium in ICU patients was significantly reduced after implementation of a nocturnal sound-reduction protocol. However, reported sleep quality did not improve. A significant difference in slope in the percentage... read more