Implementing Clinical Practice Changes in Critical Care

Lessons learned in a national collaborative of over 60 ICU teams. Improving care in the intensive care unit (ICU) is a global area of focus for clinicians worldwide. The complexity of the ICU environment, compounded by multiple... read more

Spotlight Interview: The World of Fluids

Looking at the data from a new perspective, the article "Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill" published in Critical Care Medicine in August 2017,... read more

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Precision medicine in critical care is a key part of our present and future. However, many challenges limit its application for all patients in the ICU. Complex acute illness among patients with multi-morbidity, integrated... read more

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

In patients undergoing cardiac surgery who were at moderate-to-high risk for death, a restrictive strategy regarding red-cell transfusion was noninferior to a liberal strategy with respect to the composite outcome of death... read more

Critical Care Cycling Study (CYCLIST) Trial Protocol

Critical Care Cycling Study (CYCLIST) trial protocol: a randomised controlled trial of usual care plus additional in-bed cycling sessions versus usual care in the critically ill. In-bed cycling with patients with critical... read more

Kinetic Estimated Glomerular Filtration Rate in Critically Ill Patients

Both the Acute kidney injury (AKI) classification system and the nonsteady-state (kinetic) estimated glomerular filtration rate (KeGFR) are complementary to each other. Assessing both AKI stage and KeGFR can help to identify... read more

Multicenter Assessment of Sedation and Delirium Practices in the ICU in Poland

A majority of Polish ICUs do not adhere to international guidelines regarding sedation and delirium practices. There continues to be inadequate use of sedation and delirium monitoring tools. High usage of benzodiazepines... read more

Better AKI Patient Survival Linked to Negative Fluid Balance

Optimal fluid management of critically ill patients with or at risk for acute kidney injury (AKI) is still uncertain. Now a new prospective study from India confirms that patients with negative fluid balance live longer.... read more

Long-Term Cognitive Impairment after Critical Illness

Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment. A longer duration of delirium in the hospital was associated with worse global cognition and executive function scores at 3 and 12... read more

ICU Diary Impact on Patients and Families Wellbeing

The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs. This study will provide new insights on the impact of ICU diaries on... read more

Association of the Hospital Readmissions Reduction Program Implementation With Readmission and Mortality Outcomes in Heart Failure

Among fee-for-service Medicare beneficiaries discharged after heart failure hospitalizations, implementation of the HRRP was temporally associated with a reduction in 30-day and 1-year readmissions but an increase in 30-day... read more

The Quiet Room

The grim reality for trauma healthcare clinicians. From the vantage point of a trauma surgeon, conversation seems a terribly feeble response. Gun violence, whether on the streets of Chicago or in the churches of Charleston... read more

Better Living Quality for Intensive Care

Aiming to bring "Better Living in Intensive Care" for both patients and caregivers, the French Intensive Care Society issued guidelines to promote quality of life for ICU. As the largest premier reference and teaching hospital... read more

Successful Strategy to Decrease Indwelling Catheter Utilization Rates in an Academic Medical ICU

Our interventions demonstrated that aggressive and comprehensive indwelling urinary catheters (IUCs) restriction protocol and provider training can lead to a successful decrease in IUC use, leading to a lower IUC utilization... read more

High Flow Nasal Cannula Use Outside of the ICU – Factors Associated with Failure

High FiO2 requirements, history of intubation, and cardiac co-morbidity are associative predictors of HFNC failure. Bronchiolitis patients may be treated with HFNC outside of the ICU with lower odds of failure. Two hundred... read more

Review of Strategies to Reduce CLABSI and CAUTI in Adult ICUs

Central line–associated bloodstream infection (CLABSI) and catheter-associated urinary tract infection (CAUTI) are costly and morbid. Despite evidence-based guidelines, Some intensive care units (ICUs) continue to have... read more

Are Biomarkers Ready for Prime Time?

Kyle Enfield, MD, speaks with John A. Kellum, MD, MCCM, about his talk presented at the 46th Critical Care Congress in Honolulu, Hawaii entitled, "Are Biomarkers Ready for Prime Time?" Dr. Kellum works as an Intensivist in... read more

Despite My Best Intentions

The resident looked worried and the intern was nervous. They were concerned about an elderly patient with low cardiac output heart failure. We reviewed our plans for the day, and as we entered his intensive care unit (ICU)... read more

RRT Modality in the ICU and Renal Recovery at Hospital Discharge

In this large retrospective study, intermittent hemodialysis as an initial modality was associated with lower renal recovery at hospital discharge among patients with acute kidney injury, although the difference seems somewhat... read more

Animal-assisted Activity in the ICU

Animals are being introduced into hospital settings in ever-increasing numbers. Emerging literature suggests that incorporating trained animals to assist with medical care and rehabilitation therapies can promote patient... read more

Focus on Ventilation and Airway Management in the ICU

Airway and ventilation management are particularly challenging in the intensive care unit (ICU), and are associated with high morbidity and mortality. Figure summarizes some of the more recent findings from the literature.... read more