Improving Handovers By Learning From Ferrari Team

We were able to improve our vulnerable processes by translating good practice found in two industries – aviation and motor racing – into healthcare. We were able to do this by taking into account the subtle complexities... read more

A supplemental intravenous amino acid infusion sustains a positive protein balance for 24 hours in critically ill patients

Providing supplemental amino acids to ICU patients during a 3-h period results in improved whole-body net protein balance, without an increase in amino acid oxidation. The primary objective was to investigate if a 24-h intravenous... read more

Key Steps Can Help Patients Recover From A Stay In The ICU

Chances of recovering after an ICU stay rise when families keep patients oriented, stay on top of care plans and encourage seniors to get moving. As many as 1.4 million seniors survive a stay in the ICU every year. And most... read more

Diagnostic Importance of Pulmonary Interleukin-1β and Interleukin-8 in VAP

BALF IL-1β and IL-8 are amongst the strongest markers yet identified for accurately demarcating VAP within the larger population of patients with suspected VAP. These findings have potential implications for reduction in... read more

Music and Medicine: Something Important

Every week or 2 when I don’t have a daytime shift, I set up my iPad and play piano for an hour or so. Nothing depressing or too complicated—feel-good music from the 1930s to the latest by John Legend or Coldplay. The... read more

Intensive Care Syndrome: Promoting Independence and Return to Employment (InS:PIRE)

Many patients suffer significant physical, social and psychological problems in the months and years following critical care discharge. At present, there is minimal evidence of any effective interventions to support this... read more

A tailored multicomponent program to reduce discomfort in critically ill patients

Critically ill patients are exposed to stressful conditions and experience several discomforts. The primary objective was to assess whether a tailored multicomponent program is effective for reducing self‑perceived discomfort.... read more

There are no wrong questions to ask in the ICU

A common confusion is differentiating between critical care and emergency medicine. Essentially, in emergency medicine, doctors and nurses stabilize patients and then transfer them to the appropriate area of the hospital,... read more

I help bring music to patients in intensive care

After my own experience in ICU, I became convinced of the therapeutic benefits of live music to those who are critically ill. Soothing acoustic music drifted through the clinical, high-tech ward. As the professional musician... read more

What’s the Effective Antibiotic Dosing in Critically Ill Patients?

Mortality due to severe infections in the intensive care unit (ICU) remains high despite recent therapeutic advancements. It is believed that ICU pathogens are relatively different from those in the general wards as they... read more

Use of Wearable Devices for Post-discharge Monitoring of ICU patients

Wearable devices generate signals detecting activity, sleep, and heart rate, all of which could enable detailed and near-continuous characterization of recovery following critical illness. We found that wearable devices could... read more

Critical Illness, Disability, and the Road Home

Ability to participate in the community is an important outcome for all patients after a major illness, it signposts reaching the end of the road home. A patient's ability to return to the priority tasks of daily living impacts... read more

Implementing Clinical Practice Changes in Critical Care

Lessons learned in a national collaborative of over 60 ICU teams. Improving care in the intensive care unit (ICU) is a global area of focus for clinicians worldwide. The complexity of the ICU environment, compounded by multiple... read more

Spotlight Interview: The World of Fluids

Looking at the data from a new perspective, the article "Both Positive and Negative Fluid Balance May Be Associated With Reduced Long-Term Survival in the Critically Ill" published in Critical Care Medicine in August 2017,... read more

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Precision medicine in critical care is a key part of our present and future. However, many challenges limit its application for all patients in the ICU. Complex acute illness among patients with multi-morbidity, integrated... read more

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

In patients undergoing cardiac surgery who were at moderate-to-high risk for death, a restrictive strategy regarding red-cell transfusion was noninferior to a liberal strategy with respect to the composite outcome of death... read more

Critical Care Cycling Study (CYCLIST) Trial Protocol

Critical Care Cycling Study (CYCLIST) trial protocol: a randomised controlled trial of usual care plus additional in-bed cycling sessions versus usual care in the critically ill. In-bed cycling with patients with critical... read more

Kinetic Estimated Glomerular Filtration Rate in Critically Ill Patients

Both the Acute kidney injury (AKI) classification system and the nonsteady-state (kinetic) estimated glomerular filtration rate (KeGFR) are complementary to each other. Assessing both AKI stage and KeGFR can help to identify... read more

Multicenter Assessment of Sedation and Delirium Practices in the ICU in Poland

A majority of Polish ICUs do not adhere to international guidelines regarding sedation and delirium practices. There continues to be inadequate use of sedation and delirium monitoring tools. High usage of benzodiazepines... read more

Better AKI Patient Survival Linked to Negative Fluid Balance

Optimal fluid management of critically ill patients with or at risk for acute kidney injury (AKI) is still uncertain. Now a new prospective study from India confirms that patients with negative fluid balance live longer.... read more

Long-Term Cognitive Impairment after Critical Illness

Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment. A longer duration of delirium in the hospital was associated with worse global cognition and executive function scores at 3 and 12... read more