The Association of Frailty with Post-ICU Disability, Nursing Home Admission, and Mortality

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Pre-ICU frailty status was associated with increased post-ICU disability and new nursing home admission among ICU survivors, and death among all admissions. Pre-ICU frailty status may provide prognostic information about outcomes after a critical illness. The mean age was 84.0 years. Frailty and pre-frailty were present prior to 213 (54.5%) and 140 (35.8%) of the 391 admissions, respectively. Relative to non-frailty, frailty was associated with 41% greater disability over the 6 months following a critical illness (adjusted RR 1.41, 95%CI 1.12, 1.78); pre-frailty conferred 28% greater disability (adjusted RR 1.28, 95%CI 1.01, 1.63). Frailty (OR 3.52, 95% CI 1.23, 10.08), but not pre-frailty (OR 2.01, 95% CI 0.77, 5.24), was associated with increased NH admission.

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