Tag: ketamine
Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus
Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. When cIVADs are applied in RSE, prescribing them early... read more
Subanesthetic Ketamine Infusions for the Management of Pediatric Pain in Non‐critical Care Settings
Ketamine can effectively be used as part of a multimodal analgesic regimen in pediatric patients in non‐critical care settings. Our five‐year experience using low‐dose ketamine infusions highlights an acceptable side... read more
Ketamine Sedation for Patients With Acute Behavioral Disturbance During Aeromedical Retrieval
Acute behavioural disturbance(ABD), also known as Excited Delirium Syndrome, is a medical emergency with reported mortality of 8-10%. The management of ABD usually involves a judicious combination of de-escalation techniques,... read more
Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine
Endotracheal intubation (ETI) is a high-risk procedure commonly performed in emergency medicine, critical care, and the prehospital setting. Traditional rapid sequence intubation (RSI), the simultaneous administration of... read more
Evaluation of Medetomidine-ketamine and Atipamezole for Reversible Anesthesia of Free-ranging Gray Wolves
Twenty-eight anesthetic events were carried out on 24 free-ranging Scandinavian gray wolves (Canis lupus) by darting from a helicopter with 5 mg medetomidine and 250 mg ketamine during winter in 2002 and 2003. Mean±SD doses... read more
Ketamine In Acute and Chronic Pain Management
The view of chronic pain as a symptom of a disease, rather than a disease state itself, has contributed to neglect in treating this condition. Although it is generally acknowledged that patients with chronic pain use significantly... read more
Taming the Ketamine Tiger
THOSE who anesthetize patients with ketamine (originally given the clinical investigation number CI-581) realize it is a unique pharmacological agent. Ever since its introduction into human clinical anesthesia, ketamine has... read more
Ketamine Continuous Infusion: A Reasonable Alternative to Traditional Sedatives and Analgesics?
Propofol, dexmedetomidine, and opioids are commonly used for patients requiring continuous sedation or analgesia, such as for those receiving mechanical ventilation. Although these medications are generally safe, some may... read more
Controversial US Ketamine Trial Sparks Ethics Complaint
Advocacy group alleges that emergency medical workers in Minnesota gave patients ketamine injections without consent, despite known risks. A consumer-advocacy group is filing a complaint with the US government about two clinical... read more
Thai cave rescue: The drug that allowed boys to survive rescue mission
Thai schoolboys were rescued from the cave using dissociative ketamine plus positive-pressure facemask ventilation (to prevent water from leaking into their masks), so they basically used delayed sequence intubation strategy.... read more
Intubation in Special Patient Populations: Intracranial Hemorrhage
Lidocaine has weak evidence to support its ICP blunting effects. Fentanyl may be a better choice. Ketamine is a reasonable alternative to etomidate during induction. No differnce in mortality exists between usage of succinylcholine... read more
A Nightmare Airway with Rob Bryant
In terms of airway management, cricothyrotomy is one of the most advanced airway procedures an ED physician will perform. It is a last resort procedure when a patient is not able to be ventilated/oxygenated and/or intubated.... read more
Getting Creative with Ketamine
Versatile and safe, Ketamine can help with sedation, induction, asthma and pain. Can a shot of it even treat suicidality? New indications for Ketamine seem to be popping up every day. Its primary ED use is for procedural... read more
Hemodynamic Response After Rapid Sequence Induction With Ketamine in Out-of-Hospital Patients at Risk of Shock as Defined by the Shock Index
After ketamine induction, high shock index patients exhibited blunted hypertensive responses and more frequent hypotension, whereas low shock index patients had sustained increases in pulse rate and SBP. One hundred twelve... read more
Ketamine Alters Hippocampal Cell Proliferation and Improves Learning in Mice after TBI
Ketamine alters hippocampal cell proliferation after traumatic brain injury (TBI). Surprisingly, these changes were associated with improvement in a neurogenesis-related behavioral recall task, suggesting a possible benefit... read more
Comparison of Etomidate and Ketamine for Induction During Rapid Sequence Intubation of Adult Trauma Patients
Induction doses of etomidate during rapid sequence intubation cause transient adrenal dysfunction, but its clinical significance on trauma patients is uncertain. Ketamine has emerged as an alternative for rapid sequence intubation... read more
Considerations for Physicians Using Ketamine for Sedation of Children in EDs
Ketamine use in emergency departments (EDs) for procedural sedation and analgesia is becoming increasingly common. However, few studies have examined patient factors related to adverse events associated with ketamine. This... read more