Ketamine for PTSD Treatment

Ketamine for PTSD Treatment

Post-traumatic stress disorder (PTSD) continues to be a problematic psychiatric condition that can be difficult to treat. SSRIs are the first-line treatment, and they are the only pharmaceutical class approved – their use... read more

Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

Impact of timing of continuous intravenous anesthetic drug treatment on outcome in refractory status epilepticus

Patients with refractory status epilepticus (RSE) treated with continuous intravenous anesthetic drugs (cIVADs) may benefit from early initiation of such therapy. When cIVADs are applied in RSE, prescribing them early... read more

Subanesthetic Ketamine Infusions for the Management of Pediatric Pain in Non‐critical Care Settings

Subanesthetic Ketamine Infusions for the Management of Pediatric Pain in Non‐critical Care Settings

Ketamine can effectively be used as part of a multimodal analgesic regimen in pediatric patients in non‐critical care settings. Our five‐year experience using low‐dose ketamine infusions highlights an acceptable side... read more

Ketamine Sedation for Patients With Acute Behavioral Disturbance During Aeromedical Retrieval

Ketamine Sedation for Patients With Acute Behavioral Disturbance During Aeromedical Retrieval

Acute behavioural disturbance(ABD), also known as Excited Delirium Syndrome, is a medical emergency with reported mortality of 8-10%. The management of ABD usually involves a judicious combination of de-escalation techniques,... read more

Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine

Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine

Endotracheal intubation (ETI) is a high-risk procedure commonly performed in emergency medicine, critical care, and the prehospital setting. Traditional rapid sequence intubation (RSI), the simultaneous administration of... read more

Evaluation of Medetomidine-ketamine and Atipamezole for Reversible Anesthesia of Free-ranging Gray Wolves

Evaluation of Medetomidine-ketamine and Atipamezole for Reversible Anesthesia of Free-ranging Gray Wolves

Twenty-eight anesthetic events were carried out on 24 free-ranging Scandinavian gray wolves (Canis lupus) by darting from a helicopter with 5 mg medetomidine and 250 mg ketamine during winter in 2002 and 2003. Mean±SD doses... read more

Ketamine In Acute and Chronic Pain Management

Ketamine In Acute and Chronic Pain Management

The view of chronic pain as a symptom of a disease, rather than a disease state itself, has contributed to neglect in treating this condition. Although it is generally acknowledged that patients with chronic pain use significantly... read more

Taming the Ketamine Tiger

Taming the Ketamine Tiger

THOSE who anesthetize patients with ketamine (originally given the clinical investigation number CI-581) realize it is a unique pharmacological agent. Ever since its introduction into human clinical anesthesia, ketamine has... read more

Ketamine Continuous Infusion: A Reasonable Alternative to Traditional Sedatives and Analgesics?

Ketamine Continuous Infusion: A Reasonable Alternative to Traditional Sedatives and Analgesics?

Propofol, dexmedetomidine, and opioids are commonly used for patients requiring continuous sedation or analgesia, such as for those receiving mechanical ventilation. Although these medications are generally safe, some may... read more

Controversial US Ketamine Trial Sparks Ethics Complaint

Controversial US Ketamine Trial Sparks Ethics Complaint

Advocacy group alleges that emergency medical workers in Minnesota gave patients ketamine injections without consent, despite known risks. A consumer-advocacy group is filing a complaint with the US government about two clinical... read more

Thai cave rescue: The drug that allowed boys to survive rescue mission

Thai cave rescue: The drug that allowed boys to survive rescue mission

Thai schoolboys were rescued from the cave using dissociative ketamine plus positive-pressure facemask ventilation (to prevent water from leaking into their masks), so they basically used delayed sequence intubation strategy.... read more

Intubation in Special Patient Populations: Intracranial Hemorrhage

Intubation in Special Patient Populations: Intracranial Hemorrhage

Lidocaine has weak evidence to support its ICP blunting effects. Fentanyl may be a better choice. Ketamine is a reasonable alternative to etomidate during induction. No differnce in mortality exists between usage of succinylcholine... read more

A Nightmare Airway with Rob Bryant

A Nightmare Airway with Rob Bryant

In terms of airway management, cricothyrotomy is one of the most advanced airway procedures an ED physician will perform. It is a last resort procedure when a patient is not able to be ventilated/oxygenated and/or intubated.... read more

Getting Creative with Ketamine

Getting Creative with Ketamine

Versatile and safe, Ketamine can help with sedation, induction, asthma and pain. Can a shot of it even treat suicidality? New indications for Ketamine seem to be popping up every day. Its primary ED use is for procedural... read more