Frequency of Exacerbations in Patients with COPD

Present treatment strategies to stratify exacerbation risk in patients with chronic obstructive pulmonary disease (COPD) rely on a history of two or more events in the previous year. We aimed to understand year to year variability... read more

Frequency of Exacerbations in Patients with COPD

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease

ILD is a serious complication in RA, with a significantly increased mortality compared with a large matched cohort of RA comparisons without ILD. Mortality risks were assessed using Kaplan-Meier mortality curves, and hazard... read more

A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease

Volume responsiveness and volume tolerance: a conceptual diagram

So I know I've be-laboured the point about the difference between volume responsiveness (i.e. will there be significant increase in cardiac output with volume infusion) and volume tolerance (is the volume I am considering... read more

Volume responsiveness and volume tolerance: a conceptual diagram

Lung Microbiome: Key to Respiratory Ills?

Recently, JAMA discussed this research and its potential clinical applications with 2 experts on the front lines, Jack Gilbert, PhD, a microbial ecologist at the University of Chicago and director of its new Microbiome Center... read more

Lung Microbiome: Key to Respiratory Ills?

Utility and diagnostic accuracy of bedside lung ultrasonography during MET activations for respiratory deterioration

We investigated the feasibility and diagnostic accuracy of lung ultrasonography during medical emergency team (MET) activations for respiratory deterioration. The ultrasound exam was completed in 49/50 (98%) patients enrolled... read more

Utility and diagnostic accuracy of bedside lung ultrasonography during MET activations for respiratory deterioration

Opening pressures and atelectrauma in ARDS

Data show that the prerequisites of the open lung strategy are not satisfied using PEEP up to 15 cmH2O and plateau pressure up to 30 cmH2O. For an effective open lung strategy, higher pressures are required. Therefore,... read more

Opening pressures and atelectrauma in ARDS

Effects of Neuromuscular Blockers on Transpulmonary Pressures in Moderate to Severe ARDS

Thirty patients were included, 24 with moderate ARDS and 6 with severe ARDS. NMBA infusion was associated with an improvement in oxygenation in both moderate and severe ARDS, accompanied by a decrease in both plateau pressure... read more

Effects of Neuromuscular Blockers on Transpulmonary Pressures in Moderate to Severe ARDS

Critical care ultrasonography in acute respiratory failure

CCUS combining CCE and chest ultrasonography rapidly provides valuable information in patients presenting with ARF. A pragmatic and systematic applied protocol may first evaluate how aerated is the lung and whether there... read more

Critical care ultrasonography in acute respiratory failure

COPD and Life Expectancy

COPD is the third leading cause of death after heart disease and cancer. Chronic obstructive pulmonary disease is a term for many health conditions that affect a person's lungs on a chronic basis. The condition causes... read more

COPD and Life Expectancy

Professor Wins Outstanding Investigator Award for Lung Disease Antioxidant Studies

The National Heart, Lung and Blood Institute (NHLBI) has named the recipient of its inaugural Outstanding Investigator Award: Yvonne Janssen-Heininger, PhD, professor of pathology and laboratory medicine at the Larner College... read more

Professor Wins Outstanding Investigator Award for Lung Disease Antioxidant Studies

Here is Why COPD Disrupts Lung-Repair Ability

In chronic obstructive pulmonary disease (COPD), the patients' lungs lose their ability to repair damage on their own. Scientists at the Helmholtz Zentrum München, partner in the German Center for Lung Research, now... read more

Here is Why COPD Disrupts Lung-Repair Ability

Upright CT for lung cancer therapy planning used at Chicago Proton Center

The Northwestern Medicine Chicago Proton Center will be the first proton center in the U.S. to use P-Cure new P-ARTIS CT on patients being treated for lung cancer. Traditionally, patients lie flat on their backs during CT... read more

Upright CT for lung cancer therapy planning used at Chicago Proton Center

A closer step to artificial blood

Researchers have created an artificial red blood cell that effectively picks up oxygen in the lungs and delivers it to tissues throughout the body. This artificial blood can be freeze-dried, making it easier for combat medics... read more

A closer step to artificial blood

Pulmaquin Looks Promising for Treating Lung Infections in Non-CF Bronchiectasis Patients

Aradigm has announced top-line results from two Phase 3 clinical trials of Pulmaquin (inhaled ciprofloxacin) for the treatment of patients with non-cystic fibrosis bronchiectasis (non-CF BE) who have chronic lung infections... read more

Pulmaquin Looks Promising for Treating Lung Infections in Non-CF Bronchiectasis Patients

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

Ten trials met the inclusion criteria for this review (n = 1658 participants). We found five trials to be at low risk of bias and five to be at moderate risk of bias.... read more

Recruitment manoeuvres for adults with acute respiratory distress syndrome receiving mechanical ventilation

Devil in the details: Endotracheal tube depth

According to Napoleon, "the moment of greatest vulnerability is the instant immediately after victory." In airway management, this instant occurs immediately after placement of the endotracheal tube.... read more

Devil in the details: Endotracheal tube depth

New technique keeps donor lungs viable longer

A technique that allows lungs destined for transplants to be preserved longer works well, a new Canadian study finds.... read more

New technique keeps donor lungs viable longer

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

Higher PEEP, lower peak, plateau, and driving pressures, and lower respiratory rate are associated with improved survival from ARDS.... read more

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

Can a CT Scan Determine Lung Age?

A recent study in the American Journal of Respiratory and Critical Care Medicine sought to characterize age-related lung changes using CT.... read more

Can a CT Scan Determine Lung Age?

New Treatment Guidelines for Rare Lung Disease

Clinical practice guidelines created for the treatment and diagnosis of lymphangioleiomyomatosis (LAM).... read more

New Treatment Guidelines for Rare Lung Disease