Tocilizumab vs. IVIG in Patients with Severe COVID-19 Pneumonia

Severe COVID-19 patients who received IVIG in the early phase of the disease did not show better clinical outcomes in terms of mortality, hospitalization time and intensive care unit admission compared to those who received... read more

Ventilator-associated Pneumonia Pathogenesis: Old and New Mechanisms

Ventilator-associated pneumonia (VAP), defined as a lung infection that occurs in patients after 48 hours on mechanical ventilation, is among the most frequently found nosocomial infections in intensive care units around... read more

Cardiac Intensive Care

Using a multidisciplinary, team-oriented approach, this unique title expertly covers all the latest approaches to the assessment, diagnosis, and treatment of patients with critical cardiac illness. Led by Dr David L. Brown,... read more

Cardiac Intensive Care

Clinical Respiratory Anatomy and Physiology in the ICU: Anatomophysiopathology and gasometry of patients on invasive mechanical ventilation

Breathing is a physiological process that is fundamental to life. The respiratory system can be likened to a vital pump allowing the exchange of gases between the cells of an organism and the external environment. A number... read more

Clinical Respiratory Anatomy and Physiology in the ICU: Anatomophysiopathology and gasometry of patients on invasive mechanical ventilation

Weaning Failure Prediction Using Electrocardiographic Time-frequency Analysis and Respiration Flow Signals

Weaning patients from mechanical ventilation (MV) is a crucial process that requires meticulous assessment of their ability to breathe independently without ventilatory assistance. Spontaneous breathing test (SBT) is... read more

Ventilator Management: A Pre-Hospital Perspective

The goal of this book is to provide the most up to date information on mechanical ventilation based on current research, evidence based practice and my experiences as a flight paramedic and educator. A comprehensive look... read more

Ventilator Management: A Pre-Hospital Perspective

Anesthesia Role in Sedation and Weaning From Mechanical Ventilation

This systematic review highlights the advantages of anesthetic sedation strategies, particularly the use of dexmedetomidine, methadone, or sequential sedation protocols, in improving weaning outcomes, enhancing sedation quality,... read more

Analgosedation Practice During Noninvasive Respiratory Supports

Sedation is frequently used in patients with acute respiratory failure (ARF) undergoing Noninvasive Respiratory Supports (NRSs). Current analgesic practices are becoming more standardized, with analgosedation strategies increasingly... read more

Lung-protective Ventilation Strategies for Mechanical Ventilation

This study is an important step toward optimizing mechanical ventilation strategies, addressing the interplay between mechanical power, gas exchange and long-term respiratory outcomes could further refine lung-protective... read more

Severe Adenoviral Infections: Disease Progression and Poor Prognostic Markers

Low hemoglobin, high serum ferritin, and high LDH in the second week are markers of disease progression and poor prognostic markers in severe adenoviral infections, emphasizing further research and targeted interventions. The... read more

Increased Sodium Levels Associated with Ceftriaxone Administration

Serum sodium elevation is considered a frequent manifestation in critically ill patients, with significant clinical outcomes and requiring timely management. This case report suggests a possible association between the... read more

Dynamic Left Ventricular Outflow Tract Obstruction Induced by IABP in Patient with Angioedema

Mechanical circulatory support with intra-aortic balloon pump (IABP) can aid in the treatment of cardiogenic shock but may rapidly become detrimental due to the reduction in systolic arterial afterload in patients with predispositions... read more

Glycemic Control Role in Inflammation Markers and Clinical Outcomes in Type 2 Diabetes Patients with Severe COVID-19

This study demonstrates that among hospitalized COVID-19 patients with type 2 diabetes mellitus, poor glycemic control (HbA1c ≥ 7%) correlates with increased systemic inflammation, greater disease severity, and worse clinical... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

This new book will serve as a useful resource for all pharmacists involved in the management of critically ill patients, whatever their level of experience and training. There are few textbooks aimed specifically at critical... read more

The Pharmacist’s Expanded Role in Critical Care Medicine: A Comprehensive Guide for Practitioners and Trainees

Mechanical Ventilation in Patient with Respiratory Failure

This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more

Mechanical Ventilation in Patient with Respiratory Failure

Rapid Clinical Effects of Convalescent Plasma Therapy in Severe COVID-19 ARDS

Administration of convalescent plasma (CP) in critically ill COVID-19 patients leads to a rapid and highly significant improvement of sequential organ failure assessment (SOFA) score along with improvements in respiratory... read more

Promising Prognostic Predictors in Sepsis Patients Using Lactate and Albumin Ratio

Serum Lactate/Albumin ratio and BAR ratio were significantly higher in sepsis and/or septic shock and associated with increased length of hospital stay and increased in-hospital mortality and poor clinical outcome inside... read more

Prophylactic IV Antibiotics Outcomes in Patients with Acute Severe Brain Injury on Mechanical Ventilation

Among critically ill patients with acute brain injury, prophylactic IV antibiotics were associated with less VAP but not with changes in length of stay, mortality, or neurologic outcomes. Patients with structural brain... read more

Association Between Ketamine Use and Mortality in Critically Ill Patients Receiving Mechanical Ventilation

In this retrospective study, we observed that younger patients with acute respiratory distress syndrome (ARDS) may benefit from ketamine use in terms of 14-day mortality. However, these benefits were not observed in longer-term... read more

Peritoneal Dialysis in AKI: 20 Years of Experience at a Single Center

Peritoneal dialysis (PD) may be an effective solution for acute kidney injury (AKI) patients, allowing adequate metabolic and fluid control. Age, APACHE score, hepatorenal syndrome and dropout from PD were associated... read more

Flow Control Ventilation in ICU

Flow control ventilation is an innovative technique of mechanical ventilation with a potentially lung protective characteristics. The constant inspiratory and expiratory flow, no ventilation pauses, and inspiration to... read more

ICU-acquired Weakness: Critical Illness Myopathy and Polyneuropathy

Critical illness myopathy (CIM) and critical illness polyneuropathy (CIP) are significant complications in intensive care unit (ICU) patients, first identified in the late 20th century. These conditions often present... read more