Restoring Voices: Safety and Success of In-Line Speaking Valves

A retrospective cohort study evaluated the safety and tolerability of placing a speaking valve directly in-line with the ventilator circuit for critically ill, tracheostomized patients who were difficult to wean from mechanical... read more

Non-invasive Mechanical Ventilation in Critical Care, Anesthesiology and Palliative Care

This book provides an easy, modern and practical way for physicians to approach the world of noninvasive mechanical ventilation (NIMV). Noninvasive ventilation is well-established and increasingly used in routine clinical... read more

Non-invasive Mechanical Ventilation in Critical Care, Anesthesiology and Palliative Care

PEEP’s Hidden Impact: The Rise in Mechanical Power

This study investigated how a stepwise increase in Positive End-Expiratory Pressure (PEEP) affects respiratory mechanics and mechanical power in mechanically ventilated adults. Using an incremental titration strategy,... read more

Mastering Non-Invasive Respiratory Support: A Guide to Success

This clinical guide provides an overview of non-invasive respiratory support (NIRS) techniques—including High-Flow Nasal Therapy (HFNT), Continuous Positive Airway Pressure (CPAP), and Bilevel Positive Airway Pressure (BiPAP)-for... read more

ICU Alert: Unraveling Mortality in Obstructive Pyelonephritis

This retrospective multicenter study investigated in-hospital mortality among 483 patients admitted to the ICU (8 centers) over a decade due to obstructive pyelonephritis, a severe condition often caused by kidney stones,... read more

Mechanical Ventilation in Patient with Respiratory Failure

This handbook covers the principles of mechanical ventilation, making them easy to understand and apply in clinical settings. Presented in an accessible style and supplemented by a wealth of illustrations and graphs, it includes... read more

Mechanical Ventilation in Patient with Respiratory Failure

Scarred Lungs: Identifying Fibrosis Risk After COVID-19 ARDS

This substudy of the large, multicenter RECOVIDS cohort investigated the predictive factors for developing fibrotic changes (FC) in survivors of COVID-19-related Acute Respiratory Distress Syndrome (ARDS) six months after... read more

Gut Feeling vs. Data: SDD Doesn’t Beat Standard Care for Ventilated Patients

This multi-center trial, spanning 26 Intensive Care Units (ICUs) in Australia and Canada and involving over 20,000 critically ill patients on mechanical ventilation, put a long-debated practice, Selective Decontamination... read more

The Crystal Ball of the ICU: Machine Learning Predicts Who’s Staying and Who’s Not

The PREMIER Study dove into the data of 996 patients experiencing Acute Hypoxemic Respiratory Failure (AHRF) who had been on mechanical ventilation (MV) for at least two days, aiming to develop a reliable way to predict their... read more

The Vitamin C Verdict: Not a COVID-19 Mortality Fix

This systematic review and meta-analysis investigated the efficacy of Vitamin C as a treatment for COVID-19, focusing on key patient outcomes like mortality and critical care resource utilization. Objective: To determine... read more

Mechanical Ventilation in Emergency Medicine

This book discusses mechanical ventilation in emergency settings, covering the management of patients from the time of intubation until transfer to the ICU. It provides an introduction to key concepts of physiology pertinent... read more

Mechanical Ventilation in Emergency Medicine

Corticosteroids in ARDS: Delaying High-Dose Methylprednisolone Doesn’t Kill

This large retrospective study investigated whether starting high-dose (2 mg/kg) methylprednisolone therapy after 14 days of Acute Respiratory Distress Syndrome (ARDS) onset increased the risk of complications or mortality... read more

Dexmedetomidine’s ICU Advantage: Faster Exit, Longer Stay?

This updated meta-analysis compared the outcomes of using dexmedetomidine versus other standard sedatives in mechanically ventilated patients with sepsis. Objective: To synthesize recent evidence (2020–2025) from Randomized... read more

Voice Breakthrough: Bringing Speech Back to Ventilator Patients

This retrospective cohort study investigated the safety and success of placing a speaking valve in-line with the mechanical ventilator circuit for critically ill, tracheostomized patients who struggled to wean from the ventilator. Study... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

In the present book, a broad description of the processes carried out in patients with mechanical ventilation in the ICU is made. It covers from an overview of mechanical ventilation and some of its history to the processes... read more

Mechanical Ventilation in the ICU: A New Approach and Treatment

Basics of Mechanical Ventilation

This book is a practical and easily understandable guide for mechanical ventilation. With a focus on the basics, this text begins with a detailed account of the mechanisms of spontaneous breathing as a reference point to... read more

Basics of Mechanical Ventilation

Beyond the Diaphragm: Combined Muscle Ultrasound Predicts Extubation Success in Sepsis

This prospective observational study investigated a novel approach using combined ultrasound measurements of both the diaphragm and intercostal muscles to better predict extubation outcomes in mechanically ventilated patients... read more

Most ICU Infections Miss the Mark for Classic Fever

The large number of patients being treated for infection without a high fever suggests that many could be ideal candidates for a clinical trial investigating induced hyperthermia (purposely raising body temperature) as a... read more

Melatonin for Delirium Prevention: The Sleep Hormone Doesn’t Pass the ICU Test

Despite its frequent occurrence and association with increased mortality in critically ill patients, delirium prevention remains challenging. A recent meta-analysis sought to resolve conflicting results from randomized controlled... read more

Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

The new edition presents updates regarding new clinical applications of noninvasive mechanical ventilation and discusses recent technical advances in this field. The opening sections are devoted to theory, equipment, with... read more

Noninvasive Mechanical Ventilation: Theory, Equipment, and Clinical Applications

VAEs are Real: Advanced Modeling Confirms Ventilator Events Drive Worse Outcomes

The study by Nakahashi et al. significantly advances our understanding of Ventilator-Associated Events (VAEs) by using advanced causal modeling. Their findings firmly establish that VAEs are clinically significant events... read more

Lung Ultrasound Speeds Up VAP Diagnosis and Improves ICU Outcomes

This prospective randomized controlled study investigated whether using Lung Ultrasound (LUS) as a primary bedside tool for diagnosing Ventilator-Associated Pneumonia (VAP) could outperform the standard radiological approach... read more