Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle

Effectiveness and Safety of the Awakening and Breathing Coordination, Delirium Monitoring/Management, and Early Exercise/Mobility Bundle

Critically ill patients managed with the Awakening and Breathing Coordination, Delirium monitoring/management, and Early exercise/mobility bundle spent three more days breathing without assistance, experienced less delirium,... read more

COVID-19 and AKI

COVID-19 and AKI

Recent reports from China, Italy, and the US indicate that there is a 25-37% incidence of AKI among critically ill COVID-19 patients (Singh 2020, Hirsch et al. 2020). In a study of 5,449 hospitalized COVID-19 patients, acute... read more

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

From despair to hope: advanced therapy gives a lifeline to the sickest COVID-19 patients

More than two months later, that piece of paper still lies on her coffee table with four letters on it: "E-C-M-O." Irena Veronese had never heard that acronym before, but when it was first mentioned to her, it meant moving... read more

AKI in Critically Ill Patients with COVID-19

AKI in Critically Ill Patients with COVID-19

Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-CoV-2 infection, especially in those with underlying comorbidities. AKI is associated with high mortality rates in this setting,... read more

Rescue Therapy for Severe COVID-19 Associated ARDS with tPA

Rescue Therapy for Severe COVID-19 Associated ARDS with tPA

The COVID-19 pandemic has led to unprecedented stresses on modern medical systems, overwhelming the resource infrastructure in numerous countries while presenting a unique series of pathophysiologic clinical findings. Thrombotic... read more

COVID-19: 10 Things I Wished I’d Known Some Months Ago

COVID-19: 10 Things I Wished I’d Known Some Months Ago

The COVID-19 pandemic is ongoing and spreading, affecting individuals in over 200 countries now. While COVID-19-related articles are being published every day, including guidelines of optimal clinical management, there are... read more

Prolonged Prone Position Ventilation for SARS-CoV-2 Patients is Feasible and Effective

Prolonged Prone Position Ventilation for SARS-CoV-2 Patients is Feasible and Effective

Recently, novel coronavirus 2019 (nCOV-19) is spreading all around the world causing severe acute respiratory syndrome (SARS-CoV-2) requiring mechanical ventilation in about 5% of infected people. Prone position ventilation... read more

Predictors of Care in Persons Under Investigation for COVID-19

Predictors of Care in Persons Under Investigation for COVID-19

The healthcare burden of the coronavirus disease 2019 (COVID-19) pandemic extends beyond patients who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a retrospective cohort study... read more

How to Intubate the Critically Ill Like a Boss

How to Intubate the Critically Ill Like a Boss

Despite decades of experience with endotracheal intubation, we continue to find approaches to improving the process of how we intubate. In today's post we are not only going to talk about how to avoid post intubation cardiac... read more

Implantation of Impella CP LV Assist Device Under the Guidance of 3D Intracardiac Echocardiography

Implantation of Impella CP LV Assist Device Under the Guidance of 3D Intracardiac Echocardiography

This translational study in ovine model confirms that three-dimensional intracardiac echocardiography is a feasible option to guide implantation of the Impella CP® for left ventricular mechanical support and should be considered... read more

Sharing Data is the Key to Unlocking Remdesivir Challenges

Sharing Data is the Key to Unlocking Remdesivir Challenges

Critical care teams should consider using remdesivir to treat patients with severe acute SARS-CoV-2 infection, but supply of the drug is limited and best practices for maximizing its effectiveness are not completely understood. The... read more

A Transdisciplinary COVID-19 Early Respiratory Intervention Protocol

A Transdisciplinary COVID-19 Early Respiratory Intervention Protocol

In the days after COVID-19 arrived in our region, there were many such stories of patients sent to the floor from the Emergency Department who were intubated shortly after admission. Many of those patients subsequently... read more

The Utility of Diaphragm Ultrasound in Reducing Time to Extubation

The Utility of Diaphragm Ultrasound in Reducing Time to Extubation

Predicting the optimal time for extubation is challenging, especially in patients with underlying diaphragm dysfunction. Incorporating ultrasound information on diaphragm function into usual care allowed clinicians to identify... read more

Global Effort to Collect Data on Ventilated Patients With COVID-19

Global Effort to Collect Data on Ventilated Patients With COVID-19

As the new chair of the Asia-Pacific Chapter of the Extracorporeal Life Support Organization (ELSO), John Fraser, MBChB, PhD, began talking with the group's members last November about why influenza affects some people worse... read more