Translating Evidence Into Practice in ARDS

Although the treatment of the acute respiratory distress syndrome (ARDS) with low tidal volume (LTV) mechanical ventilation improves mortality, it is not consistently administered in clinical practice. This review examines... read more

Translating Evidence Into Practice in ARDS

Single-Center Experience With Venovenous ECMO for Influenza-Related ARDS

Influenza-related ARDS has a high mortality rate and patients treated only with mechanical ventilation have worse outcome than those managed with VV ECMO. More liberal use of ECMO should be considered in patients with influenza-related... read more

Single-Center Experience With Venovenous ECMO for Influenza-Related ARDS

Simplifying Mechanical Ventilation

Mechanical Ventilation is a modality commonly used in the critically ill, but many providers, may not have a strong understanding of the basics. Emergency Medicine and Critical Care Physicians need to have a firm grasp of... read more

Simplifying Mechanical Ventilation

Lack of Association of High Backrest With Sacral Tissue Changes in Adults Receiving Mechanical Ventilation

Although higher backrest elevation may be a theoretical risk for integrity of sacral tissues, few data support use of high backrest elevation. Level of backrest elevation is not associated with changes in tissue integrity.... read more

Lack of Association of High Backrest With Sacral Tissue Changes in Adults Receiving Mechanical Ventilation

Factors Associated With Bed Utilization and Development of a Benchmarking Model

ICU length of stay (LOS) is an important measure of resource use and economic performance. Our primary aims were to characterize the utilization of PICU beds and to develop a new model for PICU length of stay. PICU bed utilization... read more

Factors Associated With Bed Utilization and Development of a Benchmarking Model

Near-Infrared Cerebral Oximetry to Predict Outcome After Pediatric Cardiac Surgery

Increased SD of a smoothed cerebral tissue oxygen saturation signal and increased depth and duration of desaturation below the 50% saturation threshold were associated with longer PICU and hospital stays and with longer duration... read more

Near-Infrared Cerebral Oximetry to Predict Outcome After Pediatric Cardiac Surgery

What Role Do Dogs Play in ICUs?

Dr. Megan Hosey PhD speaks about how dogs in the ICU can help lessen patients' pain & make them more hopeful. Getting people out of bed in intensive care units, even when they're being mechanically ventilated, is associated... read more

Finding the Best Strategy to Improve Weaning Outcomes

Respiratory muscle dysfunction, being a common cause of weaning failure, is strongly associated with prolonged mechanical ventilation (MV) and prolonged stay in intensive care units. Strategies to improve weaning outcomes... read more

Finding the Best Strategy to Improve Weaning Outcomes

Recovery After Critical Illness: Putting the Puzzle Together

In this review, we seek to highlight how critical illness and critical care affect longer-term outcomes, to underline the contribution of ICU delirium to cognitive dysfunction several months after ICU discharge, to give new... read more

Recovery After Critical Illness: Putting the Puzzle Together

The Association Between ARDS Hospital Case Volume and Mortality

In this cohort, at both an individual- and hospital-level, higher acute respiratory distress syndrome hospital case volume is associated with lower acute respiratory distress syndrome hospital mortality. We analyzed 2,686... read more

The Association Between ARDS Hospital Case Volume and Mortality

Training Approaches for the Deployment of a Mechanical Chest Compression Device

Pit-crew training, compared with standard training, did not improve team deployment of a mechanical chest device in a simulated cardiac arrest scenario. Twenty teams participated in this study, each comprising three clinicians.... read more

Training Approaches for the Deployment of a Mechanical Chest Compression Device

Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment

Assessing alveolar recruitment at different positive end-expiratory pressure (PEEP) levels is a major clinical and research interest because protective ventilation implies opening the lung without inducing overdistention.... read more

Variation of Poorly Ventilated Lung Units Measured by EIT to Dynamically Assess Recruitment

Antipsychotics for Prevention and Treatment of Delirium

Delirium is a common, complex and costly condition in older adults. Every year, over 7 million hospitalized Americans suffer from delirium. A recent systematic review found that 31% of critical care patients have delirium,... read more

Antipsychotics for Prevention and Treatment of Delirium

Bedside Limited Echocardiography by the Emergency Physician Is Accurate During Evaluation of the Critically Ill Patient

Our study suggests that PEP sonographers are capable of obtaining images that permit accurate assessment of LVF and IVC volume. BLEEP can be performed with focused training and oversight by a pediatric cardiologist. We conducted... read more

Bedside Limited Echocardiography by the Emergency Physician Is Accurate During Evaluation of the Critically Ill Patient

Early Application of APRV May Reduce the Duration of Mechanical Ventilation in ARDS

Compared with LTV, early application of airway pressure release ventilation (APRV) in patients with ARDS improved oxygenation and respiratory system compliance, decreased Pplat and reduced the duration of both mechanical... read more

Early Application of APRV May Reduce the Duration of Mechanical Ventilation in ARDS

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enteral feeding was not superior to parenteral feeding for early nutritional support in critically ill patients receiving mechanical ventilation and vasopressor support for shock, according to the results of a study published... read more

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enabling Machine Learning in Critical Care

Critical care units are home to some of the most sophisticated patient technology within hospitals. In parallel, the field of machine learning is advancing rapidly and increasingly touching our lives. To facilitate the adoption... read more

Enabling Machine Learning in Critical Care

Barriers and Facilitators to Early Rehabilitation in Mechanically Ventilated Patients

Using a theoretically driven approach, this study identified important barriers and facilitators to early rehabilitation in ICU patients. In particular, the domains of social influences and behavioral regulation were not... read more

Barriers and Facilitators to Early Rehabilitation in Mechanically Ventilated Patients

Supplemental Parenteral Nutrition vs. Usual Care in Critically Ill Adults

This individually titrated supplemental PN strategy applied over 7 days significantly increased energy delivery when compared to usual care delivery. Clinical and functional outcomes were similar between the two patient groups.... read more

Supplemental Parenteral Nutrition vs. Usual Care in Critically Ill Adults

Mechanical Ventilation Strategies for the Surgical Patient

The understanding on the protective roles of tidal volume and PEEP settings against PPCs has rapidly expanded. During intraoperative ventilation, low tidal volumes are protective, the protective role of high levels of PEEP... read more

Mechanical Ventilation Strategies for the Surgical Patient

Principles And Practice of Mechanical Ventilation

A comprehensive, authoritative coverage of all the clinical, pharmacological, and technical issues surrounding the use of mechanical ventilation. More than 100 authors, all of whom are at the forefront of research in their... read more

Principles And Practice of Mechanical Ventilation

Comparison between a nurse-led weaning protocol and weaning based on physician’s clinical judgment in tracheostomized critically ill patients

In this pilot RCT we demonstrated that a nurse-led weaning protocol from tracheostomy was feasible and safe. A larger RCT is justified to assess efficacy. We enrolled 65 patients, 27 were in the protocol group and 38 in the... read more

Comparison between a nurse-led weaning protocol and weaning based on physician’s clinical judgment in tracheostomized critically ill patients