Tag: mechanical ventilation
Factors Associated With Pediatric Ventilator-Associated Conditions in Six U.S. Hospitals
A newly proposed surveillance definition for ventilator-associated conditions among neonatal and pediatric patients has been associated with increased morbidity and mortality among ventilated patients in cardiac ICU, neonatal... read more
50 Years of Research in ARDS
Mechanical ventilation (MV) is critical in the management of many patients with the acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate... read more
Does a 1-h Rest After a Successful SBT Really Improve Extubation Outcome?
Discussion on whether reconnection to mechanical ventilation for 1h after a successful spontaneous breathing trial (SBT) reduces reintubation in critically ill patients: a multicenter randomized controlled trial.... read more
Focus on Ventilation and Airway Management in the ICU
Airway and ventilation management are particularly challenging in the intensive care unit (ICU), and are associated with high morbidity and mortality. Figure summarizes some of the more recent findings from the literature.... read more
Higher PEEP versus Lower PEEP Strategies for Patients with ARDS
Use of higher positive end-expiratory pressure (PEEP) is unlikely to improve clinical outcomes among unselected patients with ARDS. We identified eight randomized trials comparing higher versus lower PEEP strategies, enrolling... read more
The Role of Physiotherapy in Enhanced Recovery After Surgery in the ICU
Enhanced recovery after surgery (ERAS) is an evidence-based, multimodal approach to optimising patient outcomes following surgery. The role of physiotherapy within ERAS and intensive care units (ICU) is important. Patients... read more
Ultrasound-guided Mechanical Ventilation
Point-of-care ultrasound (POCUS) is now a tool used worldwide, integrating clinical assessment of the critically ill. In this review, we focus on lung, diaphragm and cardiac ultrasound in the management of the mechanically... read more
Severe AKI in Young ICU Patients Predicts Higher Mortality
Acute kidney injury (AKI) among critically ill children and young adults is common and is associated with higher mortality risk and other poor outcomes The condition also is associated with greater use of renal-replacement... read more
Aerosol Delivery During Invasive Mechanical Ventilation
Lung deposition was lower than 20% of nominal dose delivered with nebulizers and mostly occurred in proximal airways. Further studies are needed to link substantial concentrations of antibiotics in infected pulmonary fluids... read more
Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients
This prospective observational multicentre study (ARREVE) was done in 43 French ICUs to compare terminal weaning and immediate extubation, as chosen by the ICU team. Terminal weaning was a gradual decrease in the amount of... read more
Cytomegalovirus infection in immunocompetent critically ill adults
Some studies have demonstrated an association between Cytomegalovirus (CMV) disease and increased mortality rates, prolonged intensive care unit and hospital length of stay, prolonged mechanical ventilation, and nosocomial... read more
Efficacy of Combination Therapy of Shenfu Injection and Postresuscitation Bundle in Patients With Return of Spontaneous Circulation
This study demonstrates that Shenfu injection in combination with conventional postresuscitation care bundle treatment is effective at improving clinical outcomes in patients with return of spontaneous circulation after in-hospital... read more
Drug does not significantly reduce duration of mechanical ventilation for COPD patients
Among mechanically ventilated patients with COPD, administration of the respiratory stimulant acetazolamide did not significantly reduce the duration of invasive mechanical ventilation.... read more
5-Year Trends of Critical Care Practice and Outcomes
According to researchers in the U.S., analyses of patients, practices, and outcomes from a large geographically dispersed sample of adult ICUs revealed trends of increasing age and acuity, higher rates of adherence to best... read more
Benzodiazepines and Delirium in ICU Patients
We have learned an extraordinary amount about ICU delirium over the last 2 decades, which is associated with increased duration of mechanical ventilation, length of hospital stay, long-term cognitive impairment, and mortality... read more
Selepressin – An Effective Substitute for Norepinephrine
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients. Vasopressin is widely used for vasopressor... read more
Successful Long-Term ECMO for Invasive Pulmonary Aspergillosis
Extracorporeal membrane oxygenation is an established life-saving procedure for severe acute respiratory failure due to various causes. Long-term extracorporeal membrane oxygenation might be considered if the primary causes... read more
Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration
Among comatose patients receiving mechanical ventilation, those without clinical, laboratory, or radiologic evidence of bacterial aspiration pneumonia did not require antibiotics. In those with suspected bacterial aspiration... read more
High-Observation Protocol Cuts Length of Stay in Head
A high-observation protocol (HOP) appears to optimize clinical care for patients with head and neck cancer undergoing primary surgery, according to a study published online June 20 in Head & Neck. The researchers found... read more
Low Levels of Physical Activity During Critical Illness and Weaning
Physical rehabilitation can benefit critically ill patients during ICU admission, but routine clinical practice remains inconsistent nor examined in prolonged mechanical ventilation patients transferred to a specialist ventilator... read more
Rescue Strategy for Treating Severe Carbapenemase-Producing Klebsiella Pneumoniae Infections
Recent reports have suggested the efficacy of a double carbapenem (DC) combination, including ertapenem, for the treatment of carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infections. We aimed to evaluate the clinical... read more
