Tag: mechanical ventilation
5-Year Trends of Critical Care Practice and Outcomes
According to researchers in the U.S., analyses of patients, practices, and outcomes from a large geographically dispersed sample of adult ICUs revealed trends of increasing age and acuity, higher rates of adherence to best... read more
Benzodiazepines and Delirium in ICU Patients
We have learned an extraordinary amount about ICU delirium over the last 2 decades, which is associated with increased duration of mechanical ventilation, length of hospital stay, long-term cognitive impairment, and mortality... read more
Selepressin – An Effective Substitute for Norepinephrine
Selepressin, a novel selective vasopressin V1A agonist, is an effective substitute for norepinephrine in a phase IIa randomized, placebo-controlled trial in septic shock patients. Vasopressin is widely used for vasopressor... read more
Successful Long-Term ECMO for Invasive Pulmonary Aspergillosis
Extracorporeal membrane oxygenation is an established life-saving procedure for severe acute respiratory failure due to various causes. Long-term extracorporeal membrane oxygenation might be considered if the primary causes... read more
Antibiotic Therapy in Comatose Mechanically Ventilated Patients Following Aspiration
Among comatose patients receiving mechanical ventilation, those without clinical, laboratory, or radiologic evidence of bacterial aspiration pneumonia did not require antibiotics. In those with suspected bacterial aspiration... read more
High-Observation Protocol Cuts Length of Stay in Head
A high-observation protocol (HOP) appears to optimize clinical care for patients with head and neck cancer undergoing primary surgery, according to a study published online June 20 in Head & Neck. The researchers found... read more
Low Levels of Physical Activity During Critical Illness and Weaning
Physical rehabilitation can benefit critically ill patients during ICU admission, but routine clinical practice remains inconsistent nor examined in prolonged mechanical ventilation patients transferred to a specialist ventilator... read more
Rescue Strategy for Treating Severe Carbapenemase-Producing Klebsiella Pneumoniae Infections
Recent reports have suggested the efficacy of a double carbapenem (DC) combination, including ertapenem, for the treatment of carbapenem-resistant Klebsiella pneumoniae (CR-Kp) infections. We aimed to evaluate the clinical... read more
Analgosedation practices and the impact of sedation depth on clinical outcomes among patients requiring mechanical ventilation
Analgesia and sedation are cornerstone therapies for mechanically ventilated patients. Despite data showing that early deep sedation in the intensive care unit influences outcome, this has not been investigated in the emergency... read more
ECMO for Adult Respiratory Failure: 2017 Update
The use of extracorporeal membrane oxygenation (ECMO) for respiratory failure in adults is growing rapidly, driven in large part by advances in technology, which have made ECMO devices easier to implement, safer and more... read more
Humidification During Mechanical Ventilation: A Systematic Review
Mechanical ventilation (MV) suppresses the mechanisms that heat and moisturise inhaled air; hence, humidification is mandatory during MV. However, a systematic review published in the journal Critical Care finds no clear... read more
Transthoracic echocardiography: an accurate and precise method for estimating cardiac output in the critically ill patient
Cardiac output (CO) monitoring is a valuable tool for the diagnosis and management of critically ill patients. In the critical care setting, few studies have evaluated the level of agreement between CO estimated by transthoracic... read more
Using Ventilator to Control Oxygen May Be COPD Game-changer
Using a ventilator to control the level of supplemental oxygen a chronic obstructive pulmonary disease (COPD) patient receives halved patients' trips to the hospital from disease flare-ups, according to a clinical trial. British... read more
Prediction of Survival and Functional Outcomes After ICU Admission
This study assesses the 6-month discriminative accuracy of patient mortality and functional outcome predictions made by intensive care unit (ICU) physicians and nurses at the time of ICU admission. Intensive care unit physicians'... read more
Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with ARDS
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.... read more
Identifying barriers to delivering the ABCDE bundle to minimize adverse outcomes for mechanically ventilated patients
Improved outcomes are associated with the Awakening, Breathing Coordination, Delirium and Early mobility/exercise (ABCDE) bundle; however, implementation issues are common. As yet, no study has integrated the barriers to... read more
Extra Corporeal Carbon Dioxide Removal
In patients with chronic obstructive airway disease and hypercapneic acidosis, who are failing non-invasive ventilation, does extra corporeal carbon dioxide removal compared to non-invasive ventilation alone, reduce the... read more
Spontaneous Breathing during Mechanical Ventilation. Risks, Mechanisms, and Management
Spontaneous respiratory effort during mechanical ventilation has long been recognized to improve oxygenation, and because oxygenation is a key management target, such effort may seem beneficial. Also, disuse and loss of peripheral... read more
Pricey Technology Is Keeping People Alive Who Don’t Want to Live
As an ICU physician, I’ve used technologies like breathing machines and feeding tubes to save lives that would have been lost just a few decades earlier. But I’ve also seen the substantial costs, both human and financial,... read more
Family Responses to Prognostic Information in Chronic Critical Illness
Prognostic disclosure by skilled clinician communicators evokes a repertoire of responses from surrogates for the chronically critically ill. Recognition of these response patterns may help all clinicians better communicate... read more
Use of ‘tidal volume challenge’ to improve the reliability of pulse pressure variation
Fluid loading is usually the first step in the resuscitation of patients with acute circulatory failure. Fluid responsiveness is defined as the ability of the left ventricle to increase its stroke volume in response to fluid... read more
Anesthesiologists Found Underreporting Medication Errors
Medication errors are apparently significantly underreported by anesthesia providers, at least at certain institutions. These recent findings may reflect a culture of underreporting or fear of punitive action, despite the... read more
