Predictor of Weaning Outcome Using Sonographic Assessment of Post-intubation Laryngeal Obstruction

The study determined that both cuff leak volume and ultrasound-guided LACWD exhibited excellent sensitivity and specificity in predicting clinically significant upper airway blockage post-extubation, with cuff leak volume... read more

Transtracheal Ultrasound as a Preventive Tool for Endotracheal Tube Malpositioning in the ICU

Endotracheal tube (ETT) malpositioning can result in a myriad of complications. Daily chest radiographs (CXR) is the gold standard in monitoring these complications. Point-of-care transtracheal ultrasound (TTUS) is an emerging... read more

The Advanced Ventilator Book

The Advanced Ventilator Book is a companion to the best-selling The Ventilator Book and is written for clinicians who already have a solid foundation in the basics of mechanical ventilation. It goes beyond the ventilator... read more

The Advanced Ventilator Book

Factors Associated with Delayed Extubation in Post Cardiac Surgery Patients

The process of extubation is a crucial phase in postoperative care. By comprehending the elements that impact DE, healthcare providers can effectively allocate medical resources to enhance the success of weaning, extubation,... read more

Awake Veno-Venous ECMO in ICU

Extracorporeal membrane oxygenation (ECMO) is an advanced treatment for severe respiratory failure. Implantation of ECMO before invasive ventilation or extubation during ECMO has been reported and is becoming increasingly... read more

Clinical Outcomes of Early Phenotype-Desirable Antimicrobial Therapy for Enterobacterales Bacteremia

This is first study to compare clinical outcomes between patients with E coli, K pneumoniae, K oxytoca, and P mirabilis BSIs receiving early PDAT vs delayed PDAT using DOOR analysis. Receiving early phenotype-desirable... read more

Intubate Patients with Sepsis Before Midnight or When the Time Comes?

The ever-recurring decision for every clinician is to act or not to act and when to act. The balance of benefit or harm of an intervention and the optimal timing of treatment is not always clear. Intervening or not and... read more

New Insights on CRRT for ARDS

In recent times, the applications of continuous renal replacement therapy (CRRT) beyond kidney‐related conditions have been progressively increasing, and its implementation in randomized controlled trials (RCTs) specifically... read more

Single-use vs. Multiple-use Endotracheal Suction Catheters Flushed with Chlorhexidine in Mechanically Ventilated ICU Patients

The aim of this feasibility randomized controlled trial (fRCT) is to assess the practicality and impact of using single-use versus multiple-use endotracheal suction catheters flushed with chlorhexidine on the incidence of... read more

Textbook of Ventilation, Fluids, Electrolytes and Blood Gases

The Textbook of Ventilation, Fluids, Electrolytes and Blood Gases encompass essential topics for which thorough education and training is a must for any clinician who manages these patients. This book has four sections, each... read more

Textbook of Ventilation, Fluids, Electrolytes and Blood Gases

Mechanical Ventilator-Associated Pneumonia in the COVID-19 Pandemic Era

The most common pathogens isolated in our ventilator-vssociated pneumonia (VAP) patients were Acinetobacter spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Resistance to the major classes... read more

Ventilator-associated Lung Disease: A Complex Reality in the ICU

Mechanical ventilation, by tracheal intubation or tracheostomy, is the common supplementary treatment for several reasons for hospitalization. Since the advent of long-term mechanical ventilation during the polio epidemic. In... read more

Ventilator-associated Lung Disease: A Complex Reality in the ICU

Invasive Mechanical Ventilation Strategies For ICU Patients with COVID-19

Lung protective ventilation and prone positioning were used in many of the Danish ICU patients with COVID-19, but barotrauma, prolonged ventilation and death occurred frequently. A total of 774 patients were invasively... read more

7-day Fluid Balance Associated with Poor Outcomes

The net fluid balance in patients with sepsis 7 days following ICU administration was significantly related to mortality during hospitalization. Specifically, a 7-day fluid balance > 5,240 mL was associated with poor... read more

Extubation Failure Risk Prediction Model Using Bedside Ultrasound

We have established a risk prediction model for extubation failure in mechanically ventilated ICU patients. This risk model base on bedside ultrasound parameters provides valuable insights for identifying high-risk patients... read more

Successful Treatment of Unilateral Pulmonary Edema as Minimally Invasive Mitral Valve Surgery Complication

We successfully treated this patient using ECMO and independent lung ventilation. Several cases have been described in the literature, but the pathogenesis and risk factors of UPE remain unclear. Management depends on... read more

Evaluation Effects of Nebulized Hypertonic Saline and Nebulized Corticosteroids in Patients with ARDS

Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute respiratory failure as a result of diffuse lung inflammation and oedema manifested by hypoxemia and stiffness in the lungs. This study... read more

72‐h Infusion of Prostacyclin in Mechanically Ventilated Patients with Pulmonary Infection and Endotheliopathy

Acute respiratory failure (ARF) is common in critically ill patients, and 50% of patients in intensive care units require mechanical ventilation. The COVID‐19 pandemic revealed that COVID‐19 infection induced ARF... read more

Multidisciplinary Collaborative Bundled Care Improves Outcomes in ICU Patients with Endotracheal Intubation

Multidisciplinary analgesic and sedative bundled care has demonstrated the potential to decrease restraint use in patients undergoing endotracheal intubation and mechanical ventilation, reduce the need for analgesic and sedative... read more

Prediction of Prolonged Mechanical Ventilation in the ICU via Machine Learning

Early recognition of risk factors for prolonged mechanical ventilation (PMV) could allow for early clinical interventions, prevention of secondary complications such as nosocomial infections, and effective triage of hospital... read more

Mechanical Ventilation Timing in Sepsis

A recent study by Dr. Kim and colleagues examined the association between the timing of mechanical ventilation (MV) and clinical outcomes in ICU patients with sepsis. The study included 2440 adult sepsis patients from... read more

Early Tracheostomy in Ventilated COVID-19 Patients Reduces VAP Incidence

Tracheostomy can reduce mechanical ventilation (MV) duration, ICU and hospital length of stay (LOS), and ventilator-associated pneumonia (VAP) risk in critically ill patients. The timing of tracheostomy in COVID-19 patients... read more