Tag: microbiome
Decreased Intestinal Microbiome Diversity in Pediatric Sepsis
Intestinal dysbiosis was associated with altered short-chain fatty acid metabolites in children with sepsis, but these findings were not linked directly to mitochondrial or immunologic changes. More detailed mechanistic studies... read more
Should fecal microbial transplantation be used in the ICU?
FMT has become an attractive option to mitigate multiple organ dysfunction in the ICU. This article discusses the physiology, rationale, early experience, and expectations for such therapy in the critically ill patient. The... read more
Evidence Backs Giving Probiotics with Antibiotics
So much of what we're told to do calls for sweeping practice changes or titanic additions to our routine approach. My own articles have advocated for tremendous shifts in typical techniques, and one need not look far to find... read more
Meet the trillions of viruses that make up your virome
If you think you don’t have viruses, think again. It may be hard to fathom, but the human body is occupied by large collections of microorganisms, commonly referred to as our microbiome, that have evolved with us since... read more
I Contain Multitudes: The Microbes Within Us and a Grander View of Life
Joining the ranks of popular science classics like The Botany of Desire and The Selfish Gene, a groundbreaking, wondrously informative, and vastly entertaining examination of the most significant revolution in biology since... read more
Nutrition in Surgery and Critical Care
DCRI Perioperative Nutrition focuses on the study of hospital-based treatments to improve preparation and recovery from surgery, major illness, and critical care. We put real science into improving patients' lives with interventions... read more
Admission to the ICU is Associated With Changes in the Oral Mycobiome
A prospective exploratory study was conducted to characterize the oral mycobiome at baseline and determine whether changes occur after admission to the intensive care unit (ICU). We found that ICU admission is associated... read more
Lung Microbiome: Key to Respiratory Ills?
Recently, JAMA discussed this research and its potential clinical applications with 2 experts on the front lines, Jack Gilbert, PhD, a microbial ecologist at the University of Chicago and director of its new Microbiome Center... read more
Disruption of the microbiota across multiple body sites in critically ill children
Microbiota in critically ill children differs sharply from the microbiota of healthy children and adults. Acknowledgement of dysbiosis associated with critical illness could provide opportunities to modulate the microbiota... read more
