Alleviating ICU Survivors’ Burden

Alleviating ICU Survivors’ Burden

In a review paper, a team of international researchers highlights how critical illness and critical care affect longer-term outcomes. According to the authors, the severity of acute illness determines the degree of impairment... read more

Inpatient antiviral treatment reduces ICU admissions among influenza patients

Inpatient antiviral treatment reduces ICU admissions among influenza patients

Administering inpatient antiviral influenza treatment may reduce admissions to the ICU among adults hospitalized with flu, according to a study presented at ID Week 2017, an infectious diseases meeting. While interventions... read more

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Challenges and Opportunities for a Precision Medicine Approach to Critical Illness

Precision medicine in critical care is a key part of our present and future. However, many challenges limit its application for all patients in the ICU. Complex acute illness among patients with multi-morbidity, integrated... read more

Enhancing Delirium Case Definitions in Electronic Health Records

Enhancing Delirium Case Definitions in Electronic Health Records

Delirium is an acute confusional state, associated with morbidity and mortality in diverse medically ill populations. Delirium may be better captured by composite outcomes, including both administrative claims data and elements... read more

Frailty Association with Perioperative Morbidity in Patients After Ambulatory General Surgery Operations

Frailty Association with Perioperative Morbidity in Patients After Ambulatory General Surgery Operations

Frailty is associated with increased perioperative morbidity in common ambulatory general surgery operations, independent of age, type of anesthesia, and other comorbidities. Surgeons should consider frailty rather than chronological... read more

Reduced Risk of Acute Exacerbation of COPD after Bariatric Surgery

Reduced Risk of Acute Exacerbation of COPD after Bariatric Surgery

Obesity is common among individuals with chronic obstructive pulmonary disease (COPD) and associated with increased COPD morbidities. However, little is known about the impact of weight reduction on COPD-related outcomes... read more

Organ Dysfunction, Injury and Failure in Acute Heart Failure

Organ Dysfunction, Injury and Failure in Acute Heart Failure

Managing patients with AHF remains a clinical challenge and current therapies have uncertain impacts on long-term morbidity and mortality. The use of therapies that prevent or reverse congestion-induced organ injury may represent... read more

PICU Repeated and Unplanned Readmissions Within 1 Year

PICU Repeated and Unplanned Readmissions Within 1 Year

Unplanned readmissions occurred in a sizable minority of PICU patients. Patients with complex chronic conditions and particular conditions were at much higher risk for readmission. In this multi-institutional study, we found... read more

The "Quality Minute" – A New, Brief, and Structured Technique for Quality Improvement Education During the Morbidity and Mortality Conference

The "Quality Minute" – A New, Brief, and Structured Technique for Quality Improvement Education During the Morbidity and Mortality Conference

The Quality Minute is a brief, structured presentation designed to incorporate quality improvement (QI) education into the surgical morbidity and mortality (M&M) conference. The 6-slide, 5-minute structure makes it easy... read more

Aspirin therapy in patients with ARDS is associated with reduced ICU mortality

Aspirin therapy in patients with ARDS is associated with reduced ICU mortality

Acute respiratory distress syndrome (ARDS) is a common clinical syndrome with high mortality and long-term morbidity. To date there is no effective pharmacological therapy. Aspirin therapy has recently been shown to reduce... read more

Prevention of AKI and protection of renal function in ICU

Prevention of AKI and protection of renal function in ICU

Acute kidney injury (AKI) in the intensive care unit is associated with significant mortality and morbidity. The results of recent randomised controlled trials have allowed the formulation of new recommendations and/or increase... read more

Malbrain Fluid Overload

Malbrain Fluid Overload

Fluid overload is associated with increased morbidity and mortality. In this presentations an overview is given of the different definitions followed by a step-by-step description of the deleterious effects of fluid overload... read more

Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Blood pressure deficits in acute kidney injury: not all about the mean arterial pressure?

Acute kidney injury (AKI) is associated with increased morbidity and mortality. Although there are many causes of AKI, it is known that patients undergoing high-risk surgery are known to be at significant risk. Although much... read more

The Prevalence of Acute Critical Neurological Disease in Children

The Prevalence of Acute Critical Neurological Disease in Children

Neurologic insults are a significant pediatric international health issue. They are frequent and contribute substantial morbidity and mortality. These data suggest a need for an increased focus on acute critical neurologic... read more

Clinical practice guideline on diagnosis and treatment of hyponatraemia

Clinical practice guideline on diagnosis and treatment of hyponatraemia

Hyponatraemia, defined as a serum sodium concentration <135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms,... read more