Post-discharge Impact of Healthcare-associated Infections in a Developing Country

Post-discharge Impact of Healthcare-associated Infections in a Developing Country

The impact of healthcare-associated infections (HCAIs) on in-hospital mortality, morbidity, length-of-stay, and costs has been extensively reported. However, few studies have focused on the follow-up of HCAI-affected subjects... read more

Withholding or Withdrawing of Life-sustaining Therapy in Older Adults Admitted to the ICU

The most important patient variables associated with the instigation of Life-sustaining Therapy (LST) limitation were acute admission, frailty, age, admission SOFA score and country. LST limitation was identified in 1356/5021... read more

It Is Important to Talk About Death

It Is Important to Talk About Death

Changes to the rules on organ donation will "reframe" the way people talk about death, a top critical care doctor said today. Dr Matt Morgan said the introduction of "deemed consent" in Wales almost four years ago – a similar... read more

Early Prediction of Prognosis in Elderly Acute Stroke Patients

Early Prediction of Prognosis in Elderly Acute Stroke Patients

Acute stroke has a high morbidity and mortality in elderly population. Baseline confounding illnesses, initial clinical examination, and basic laboratory tests may impact prognostics. In this study, we aimed to establish... read more

Association of Age With Short-term and Long-term Mortality Among Patients Discharged From ICUs in France

Association of Age With Short-term and Long-term Mortality Among Patients Discharged From ICUs in France

Results of this study suggest that aging was associated with an increased risk of mortality in the 3 years after hospital discharge that included an ICU admission, with a sharp increase in those 80 years and older. However,... read more

In-hospital Mortality Associated with the Misdiagnosis or Unidentified Site of Infection at Admission

In-hospital Mortality Associated with the Misdiagnosis or Unidentified Site of Infection at Admission

Rapid detection, early resuscitation, and appropriate antibiotic use are crucial for sepsis care. Accurate identification of the site of infection may facilitate a timely provision of appropriate care. We aimed to investigate... read more

Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With ARF

Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With ARF

Among critically ill immunocompromised patients with acute respiratory failure (ARF), high-flow oxygen therapy did not significantly decrease day-28 mortality compared with standard oxygen therapy. Of 778 randomized patients... read more

Reproducibility Trial Publishes Two Conclusions For One Paper

Reproducibility Trial Publishes Two Conclusions For One Paper

The British Journal of Anaesthesia's unusual experiment is designed to broaden replicability efforts beyond just methods and results. How deeply an anaesthetist should sedate an elderly person when they have surgery is... read more

The Epidemiology of Symptomatic Catheter-associated Urinary Tract Infections in the ICU

The Epidemiology of Symptomatic Catheter-associated Urinary Tract Infections in the ICU

Catheter-associated urinary tract infection (CAUTI) occurs frequently in critical illness with significant morbidity, mortality, and additional hospital costs. The epidemiology of symptomatic ward-acquired CAUTI (within 48... read more

Disease History to Predict Mortality Risk in ICU Patients

Disease History to Predict Mortality Risk in ICU Patients

Patients in the intensive care unit are highly heterogeneous, and include elderly patients who generally have a long history of disease. Prediction of prognosis can often be difficult because of the severity of patient illness... read more

Impact of Mean Arterial Pressure Fluctuation on Mortality in Critically Ill Patients

Impact of Mean Arterial Pressure Fluctuation on Mortality in Critically Ill Patients

The purpose of this study was to investigate the association between mean arterial pressure fluctuations and mortality in critically ill patients admitted to the ICU. The reduced mean arterial pressure fluctuation (within... read more

Outcomes and Costs of Patients Admitted to the ICU Due to Spontaneous Intracranial Hemorrhage

Outcomes and Costs of Patients Admitted to the ICU Due to Spontaneous Intracranial Hemorrhage

Spontaneous intracranial hemorrhage, including subarachnoid hemorrhage and intracerebral hemorrhage, is associated with significant morbidity and mortality. Although many of these patients will require ICU admission, little... read more

Excited Delirium: Acute Management in the ED Setting

Excited Delirium: Acute Management in the ED Setting

Excited delirium syndrome is a common yet poorly characterized ED presentation with a wide differential diagnosis. Patients are often identified initially by law enforcement, but attempts to control individuals experiencing... read more

Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors

Risk Factors at Index Hospitalization Associated With Longer-term Mortality in Adult Sepsis Survivors

In this cohort study of 94 748 adult sepsis survivors, age, male sex, 1 or more severe comorbidities, prehospitalization dependency, nonsurgical status, acute severity of illness, site of infection, and organ dysfunction... read more