Tag: mortality
Delays in Antibiotic Administration for Sepsis
Todd Fraser, MD, speaks with Christopher W. Seymour, MD, MSc, about the article, "Delays From First Medical Contact to Antibiotic Administration for Sepsis," published in Critical Care Medicine. Dr. Seymour's article contends... read more
External validation of a biomarker and clinical prediction model for hospital mortality in ARDS
Mortality prediction in ARDS is important for prognostication and risk stratification. However, no prediction models have been independently validated. We validated a mortality prediction model for ARDS that includes age,... read more
Validation of the Vasoactive-Inotropic Score in Pediatric Sepsis
Secondary retrospective analysis of a single-center sepsis registry. Vasoactive-Inotropic Score in pediatric sepsis patients is independently associated with important clinically relevant outcomes including ICU length of... read more
Acute Lung Failure – Our Evolving Understanding of ARDS
Since Laennec described the gross pathology of idiopathic anasarca of the lungs in 1821, mortality due to the acute respiratory distress syndrome has been vastly reduced. Yet the poor subsequent condition of ARDS survivors... read more
SOFA Effective Pediatric Version
An age-adjusted version of the Sequential Organ Failure Assessment score for sepsis has been found to be at least as good, if not better than, other pediatric organ dysfunction scores at predicting in-hospital mortality.... read more
Mechanisms of Severe Mortality-associated Bacterial Co-infections Following Influenza Virus Infection
The mechanisms of severe morbidity following influenza-bacteria co-infections mainly include failure of an antibacterial immune response and pathogen synergy. Moreover, failure to resume function and tolerance might be one... read more
Direct Oral Anticoagulant- or Warfarin-Related Major Bleeding
Direct oral anticoagulants (DOACs) have expanded the armamentarium for antithrombotic therapy. Although DOAC-related major bleeding was associated with favorable outcomes compared with warfarin in clinical trials, warfarin... read more
Targeted Temperature Management and Neurologic Outcome After Out-of-Hospital Cardiac Arrest
In this randomized clinical trial enrolling 355 adults with out-of-hospital cardiac arrest, there was no significant difference in favorable neurologic outcome at 6 months for those treated for 48 hours (69%) vs 24 hours... read more
Effects of Polymyxin B Hemoperfusion on Mortality in Patients With Severe Sepsis and Septic Shock
Several studies have reported a survival benefit for polymyxin B hemoperfusion treatment in patients with severe sepsis and septic shock. However, recently, a propensity-matched analysis and a randomized controlled trial... read more
Organ Dysfunction, Injury and Failure in Acute Heart Failure
Managing patients with AHF remains a clinical challenge and current therapies have uncertain impacts on long-term morbidity and mortality. The use of therapies that prevent or reverse congestion-induced organ injury may represent... read more
Are We Creating Survivors or Victims in Critical Care?
Delivering targeted nutrition to improve outcomes. Over the last 10 years, we are proud of the fact we have finally begun to reduce in-hospital mortality following severe sepsis in some countries worldwide. Further, mortality... read more
The "Quality Minute" – A New, Brief, and Structured Technique for Quality Improvement Education During the Morbidity and Mortality Conference
The Quality Minute is a brief, structured presentation designed to incorporate quality improvement (QI) education into the surgical morbidity and mortality (M&M) conference. The 6-slide, 5-minute structure makes it easy... read more
Drink Coffee and Live Longer: Cohort Study
A multinational cohort study on coffee drinking and mortality in 10 European countries. Coffee drinking was associated with reduced risk for death from various causes. This relationship did not vary by country. 521, 330 people... read more
The Role of Oliguria and the Absence of Fluid Administration and Balance Information in Illness Severity Scores
Urinary examination has formed part of patient assessment since the earliest days of medicine. Current definitions of oliguria are essentially arbitrary, but duration and intensity of oliguria have been associated with an... read more
The Complexities of Intravenous Fluid Research: Questions of Scale, Volume, and Accumulation
Despite near ubiquity, information regarding fluids consumption at a health care systems level, and patient exposure at an individual level, is surprisingly limited in the medical literature. The epidemiology of the foundational... read more
A population-based cohort study of rheumatoid arthritis-associated interstitial lung disease
ILD is a serious complication in RA, with a significantly increased mortality compared with a large matched cohort of RA comparisons without ILD. Mortality risks were assessed using Kaplan-Meier mortality curves, and hazard... read more
Impact of End-Stage Renal Disease and Acute Kidney Injury on ICU Outcomes in Patients With Sepsis
Patients with sepsis having AKI have a higher mortality rate than those with ESRD and non-KI. Hospital and ICU mortality rates for patients with ESRD were similar to non-KI patients. Late AKI compared to early AKI had a higher... read more
Electroencephalography Predicts Poor and Good Outcomes After Cardiac Arrest
The prognostic role of electroencephalography during and after targeted temperature management in postcardiac arrest patients, relatively to other predictors, is incompletely known. We assessed performances of electroencephalography... read more
