Immunotherapy

Immunotherapy

The field of immuno-oncology continues to rapidly evolve as new insights to fight and treat cancer emerge. The fourth edition of Immunotherapy provides the most current overview of immuno-oncology in different cancer types... read more

ECMO in Children Receiving HCT and Immune Effector Cell Therapy

ECMO in Children Receiving HCT and Immune Effector Cell Therapy

Use of extracorporeal membrane oxygenation (ECMO) in children receiving hematopoietic cell transplantation (HCT) and immune effector cell therapy is controversial and evidence-based guidelines have not been established. Remarkable... read more

Critical Illness and Cardiac Dysfunction in Anthracycline-Exposed Pediatric Oncology Patients

Critical Illness and Cardiac Dysfunction in Anthracycline-Exposed Pediatric Oncology Patients

Children with cancer who received anthracyclines, especially at higher doses, and who develop cardiac dysfunction are at higher risk of critical illness, have higher rates of multiple organ dysfunction and higher rates of... read more

Also Human: The Inner Lives of Doctors

Also Human: The Inner Lives of Doctors

From ER and M*A*S*H to Grey's Anatomy and House, the medical drama endures for good reason: we're fascinated by the people we must trust when we are most vulnerable. In Also Human, vocational psychologist Caroline Elton introduces... read more

Attitudes, Beliefs, and Awareness of Graduate Medical Education Trainees Regarding Palliative Care

Attitudes, Beliefs, and Awareness of Graduate Medical Education Trainees Regarding Palliative Care

Surgical trainees and trainees without previous PC rotation had significantly less awareness of PC. Overall, trainees perceived PC as beneficial to patients and capable of reducing costs while increasing survival; they also... read more

Patient-reported Outcomes Included Into Daily Practice

Patient-reported Outcomes Included Into Daily Practice

Measuring relevant outcomes in a timely manner is a priority in a health care system increasingly focused on the delivery of high-value care. Most quality measures focus on care processes or downstream outcomes such as survival;... read more

Delirium in Advanced Cancer Patients Worsens Survival

Delirium in Advanced Cancer Patients Worsens Survival

Patients with advanced cancer who arrived at the ED with delirium had increased rates of hospitalization and ICU admissions, as well as shorter survival rates, according to a study published in The Oncologist. Many patients... read more

The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients

The Intensive Care Medicine Research Agenda on Critically Ill Oncology and Hematology Patients

Over the coming years, accelerating progress against cancer will be associated with an increased number of patients who require life‑sustaining therapies for infectious or toxic chemotherapy‑related events. Major changes... read more

Association of Attitudes Regarding Overuse of Inpatient Laboratory Testing With Health Care Provider Type

Association of Attitudes Regarding Overuse of Inpatient Laboratory Testing With Health Care Provider Type

Routine hospital laboratory testing is common, and unnecessary tests can harm patients. Multiple professional societies have recommended against routine laboratory testing in hospitalized patients. Advanced practice health... read more

Personalised Medicine in Intensive Care

Personalised Medicine in Intensive Care

The specialty of intensive care medicine grew out of the realisation that critically ill patients needed more attention and specialised treatment than could be provided on a general ward, and that many of these patients had... read more

Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History

Benefits of PCI for STEMI Not Attenuated in Patients With a Cancer History

Having a history of cancer does not worsen outcomes for patients with STEMI who undergo primary PCI and should not be a barrier to revascularization and optimal therapy.... read more

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

New Cytokine Approach is Synergistic With Checkpoint Inhibitors

Among the new agents currently being explored in clinical trials, NKTR-214 stands out as a new cytokine therapy approach that could show additive benefit when combined with checkpoint inhibitors. ... read more

Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients

Frontline PARP inhibitor shrinks tumors in BRCA-positive breast patients

All 13 newly diagnosed breast cancer patients with BRCA mutations had their tumors shrink significantly when treated with a PARP inhibitor ahead of frontline presurgical chemotherapy in a pilot study at The University of... read more

Early Palliative Care Improves Quality of Life for Terminal Cancer Patients

Early Palliative Care Improves Quality of Life for Terminal Cancer Patients

The new study included 350 patients recently diagnosed with incurable lung or gastrointestinal cancer. They were randomly assigned to one of two care groups. One group received early palliative care integrated with cancer... read more

Utilising the immune system in the fight against sepsis – On Medicine

Utilising the immune system in the fight against sepsis – On Medicine

In this blog, Dr. Naoshi Takeyama, Senior Editor of Journal of Intensive Care, discusses about how knowledge of immuno-oncology can also be applied to strategies for managing sepsis and severe trauma.... read more