Management of Peripheral Venoarterial ECMO in Cardiogenic Shock

Extracorporeal membrane oxygenation (ECMO) is a powerful mechanical circulatory support modality capable of rapidly restoring systemic perfusion yet lacking in defined approaches to management. Adopting a management approach... read more

Management of Peripheral Venoarterial ECMO in Cardiogenic Shock

Epinephrine, Inodilator, or No Inotrope in VA-ECMO Implantation

Early epinephrine therapy within the first 24 h after cannulation for venoarterial extracorporeal membrane oxygenation (VA-ECMO) was associated with poor survival compared to patients with or without any inodilator therapy.... read more

Epinephrine, Inodilator, or No Inotrope in VA-ECMO Implantation

Oxygen Treatment in Intensive Care and Emergency Medicine

Hypoxemia should certainly be avoided, but the fact that the liberal administration of oxygen to patients in intensive care units and emergency rooms tends to increase morbidity and mortality implies the advisability of a... read more

Oxygen Treatment in Intensive Care and Emergency Medicine

Platelet Function During ECMO in Adult Patients

Employing impedance aggregometry and flow cytometry, we found both impaired platelet aggregation and decreased platelet activation on day 1 of Extracorporeal Membrane Oxygenation (ECMO) support compared with healthy controls.... read more

Platelet Function During ECMO in Adult Patients

Lung Recruitability in Severe ARDS Requiring ECMO

Significant variability in potential for lung recruitment in patients with severe acute respiratory distress syndrome (ARDS) requiring extracorporeal membrane oxygenation (ECMO). 47 adults with severe ARDS requiring ECMO... read more

Lung Recruitability in Severe ARDS Requiring ECMO

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Transfusion of red blood cells is an everyday practice in critical care with the primary aim of restoring adequate tissue oxygenation. However, blood transfusion may also be harmful and costly, therefore a so called restrictive... read more

The Role of Central Venous Oxygen Saturation (ScvO2) as an Indicator of Blood Transfusion in the Critically Ill

Risk Factors Associated with 30-day Mortality for Out-of-Center ECMO Support

Out-of-hospital extracorporeal membrane oxygenation (ECMO) implantation and ECMO transport have become a growing field useful for emergent treatment of heart or lung failure with increasing number of centers launching such... read more

Risk Factors Associated with 30-day Mortality for Out-of-Center ECMO Support

Interhospital Transport on Extracorporeal Membrane Oxygenation of Neonates

In recent years the number of extracorporeal membrane oxygenation (ECMO) cases in neonates has been relatively constant. Future expansion lays in new indications for treatment. Regionalization to high-volume ECMO centers... read more

Interhospital Transport on Extracorporeal Membrane Oxygenation of Neonates

ECMO and Bloodstream Infection in Congenital Diaphragmatic Hernia

The objective of this review is to characterize the risk of bloodstream infection (BSI) and urinary tract infection (UTI) and describe antibiotic use in infants with congenital diaphragmatic hernia (CDH) requiring extracorporeal... read more

ECMO and Bloodstream Infection in Congenital Diaphragmatic Hernia

Hemodynamic Impact of Oxygen Desaturation During Tracheal Intubation Among Critically Ill Children With Cyanotic and Noncyanotic Heart Disease

Oxygen desaturation was more commonly observed during tracheal intubation in children with cyanotic versus noncyanotic heart disease. However, hemodynamic tracheal intubation associated event rates were similar. In both groups,... read more

Hemodynamic Impact of Oxygen Desaturation During Tracheal Intubation Among Critically Ill Children With Cyanotic and Noncyanotic Heart Disease

Does Head of Bed Elevation During Intubation Improve Patient Oriented Outcomes?

To date the study that has shown the biggest benefit to HOB elevation is the 2016 study performed by Khandelwal and colleagues in a teaching hospital system in Seattle, WA. 528 patients managed by anesthesiologists... read more

Does Head of Bed Elevation During Intubation Improve Patient Oriented Outcomes?

Prevalence and outcome of heparin-induced thrombocytopenia diagnosed under veno-arterial extracorporeal membrane oxygenation

Prevalence of HIT among patients under VA‑ECMO is extremely low at 0.36% with an associated mortality rate of 33.3%, which appears to be in the same range as that observed in patients treated with VA‑ECMO without HIT.... read more

Prevalence and outcome of heparin-induced thrombocytopenia diagnosed under veno-arterial extracorporeal membrane oxygenation

Study of the Effects of Epinephrine on Cerebral Oxygenation and Metabolism During Cardiac Arrest and Resuscitation by Hyperspectral Near-Infrared Spectroscopy

Epinephrine administration by bolus resulted in transient improvements in cerebral oxygenation and metabolism, whereas continuous epinephrine infusion did not, compared with placebo. Future studies are needed to evaluate... read more

Study of the Effects of Epinephrine on Cerebral Oxygenation and Metabolism During Cardiac Arrest and Resuscitation by Hyperspectral Near-Infrared Spectroscopy

Oxygen Use, Lower Lung Function Seen as Predictors of Death or Transplant in IPF

The use of oxygen at rest is associated with a greater likelihood of death or lung transplant in people with idiopathic pulmonary fibrosis (IPF), a study shows. The results also showed that lower lung function at the start... read more

Oxygen Use, Lower Lung Function Seen as Predictors of Death or Transplant in IPF

Minimizing Catecholamines and Optimizing Perfusion

The main goal of hemodynamic resuscitation in shock is to improve tissue perfusion and oxygenation. As these cannot be directly evaluated at bedside in routine practice, physicians are left with surrogates such as perfusion... read more

Minimizing Catecholamines and Optimizing Perfusion

Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With ARF

Among critically ill immunocompromised patients with acute respiratory failure (ARF), high-flow oxygen therapy did not significantly decrease day-28 mortality compared with standard oxygen therapy. Of 778 randomized patients... read more

Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With ARF

Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine

Endotracheal intubation (ETI) is a high-risk procedure commonly performed in emergency medicine, critical care, and the prehospital setting. Traditional rapid sequence intubation (RSI), the simultaneous administration of... read more

Alternatives to Rapid Sequence Intubation: Contemporary Airway Management with Ketamine

Sedation Practice in ECMO-Treated Patients with ARDS

Our objective was to characterize sedation management in adult patients with severe respiratory distress syndrome (ARDS) treated with venovenous extracorporeal membrane oxygenation (VV-ECMO). We conducted a retrospective... read more

Sedation Practice in ECMO-Treated Patients with ARDS

How Should ECMO Initiation and Withdrawal Decisions Be Shared?

Extracorporeal membrane oxygenation (ECMO) is a new technology used to rescue patients with severe circulatory or respiratory failure and help bridge them to recovery or to definitive therapies like device implantation or... read more

How Should ECMO Initiation and Withdrawal Decisions Be Shared?

Economic Evaluation of vv-ECMO for Severe ARDS

Venovenous extracorporeal membrane oxygenation (vv-ECMO) is increasingly being used to support patients with severe acute respiratory distress syndrome (ARDS), but its cost-effectiveness is unknown. The cost-utility of vv-ECMO... read more

Economic Evaluation of vv-ECMO for Severe ARDS

ECMO Use in Cardiogenic Shock

Increasing age is a well-recognized risk factor for in-hospital mortality in patients receiving extracorporeal membrane oxygenation (ECMO) for cardiogenic shock, but the shape of this relationship is unknown. Age is linearly... read more

ECMO Use in Cardiogenic Shock