Monitoring of the Adult Patient on VA ECMO

Monitoring of the Adult Patient on VA ECMO

Venoarterial extracorporeal membrane oxygenation (VA ECMO), a form of mechanical circulatory support, had its origins in the operating room as cardiopulmonary bypass and has evolved for use in the intensive care unit and... read more

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual Therapy Using Sildenafil and Milrinone Superior to Monotherapy in Neonates with Severe PPHN

Dual therapy using sildenafil and milrinone was superior to monotherapy with either drug in neonates with severe persistent pulmonary hypertension (PPHN) and is recommended for use in resource-constrained settings. A double-blind... read more

Consequences of Cardiopulmonary Bypass: What the Intensivist Needs to Know

Consequences of Cardiopulmonary Bypass: What the Intensivist Needs to Know

Cardiopulmonary bypass (CPB) is common for most cardiac surgeries. CPB drains blood from the heart and returns it to the proximal systemic circulation allowing perfusion during the operative period. It was pioneered in 1951... read more

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

VA-ECMO to Rescue Sepsis-induced Cardiogenic Shock

Patients with sepsis-induced cardiomyopathy with cardiogenic shock have a high mortality. This study assessed venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for sepsis-induced cardiogenic shock refractory... read more

Factors Behind Decline of VV ECMO to Support Neonatal Respiratory Failure

Factors Behind Decline of VV ECMO to Support Neonatal Respiratory Failure

The majority of U.K. centers are unable to provide venovenous extracorporeal membrane oxygenation (VV ECMO) for neonates due to concerns with availability and suitability of dual lumen cannulae. An alternative to be considered... read more

Safety and Feasibility of Early Physical Therapy for Patients on ECMO

Safety and Feasibility of Early Physical Therapy for Patients on ECMO

With a highly trained multidisciplinary team and a focus on restoring function, it is feasible and safe to deliver early rehabilitation including standing and ambulation to patients on extracorporeal membrane oxygenation... read more

Inhaled Pulmonary Vasodilators

Inhaled Pulmonary Vasodilators

Confusion between inhaled versus intravenous routes for pulmonary vasodilators. For optimal clinical benefit (especially regarding oxygenation), these agents must be given via an inhaled route. The misconception that inhaled... read more

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Lenzilumab Showed Rapid Clinical Improvement in 12 COVID-19 Patients

Humanigen, the clinical stage biopharmaceutical company focused on preventing and treating cytokine storm, has reported positive data from the first clinical use of lenzilumab, its humaneered anti-human granulocyte macrophage-colony... read more

Thousands Who Got COVID-19 in March Are Still Sick

Thousands Who Got COVID-19 in March Are Still Sick

COVID-19 has existed for less than six months, and it is easy to forget how little we know about it. The standard view is that a minority of infected people, who are typically elderly or have preexisting health problems,... read more

The Perils of Premature Phenotyping in COVID-19

The Perils of Premature Phenotyping in COVID-19

The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) poses an unprecedented global healthcare challenge. Severe novel Coronavirus disease (COVID-19) pneumonia frequently causes hypoxemic respiratory failure, manifesting... read more

Prolonged Prone Position Ventilation for SARS-CoV-2 Patients is Feasible and Effective

Prolonged Prone Position Ventilation for SARS-CoV-2 Patients is Feasible and Effective

Recently, novel coronavirus 2019 (nCOV-19) is spreading all around the world causing severe acute respiratory syndrome (SARS-CoV-2) requiring mechanical ventilation in about 5% of infected people. Prone position ventilation... read more

Predictors of Care in Persons Under Investigation for COVID-19

Predictors of Care in Persons Under Investigation for COVID-19

The healthcare burden of the coronavirus disease 2019 (COVID-19) pandemic extends beyond patients who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), according to a retrospective cohort study... read more

How to Intubate the Critically Ill Like a Boss

How to Intubate the Critically Ill Like a Boss

Despite decades of experience with endotracheal intubation, we continue to find approaches to improving the process of how we intubate. In today's post we are not only going to talk about how to avoid post intubation cardiac... read more

Long-Term Health-Related Quality of Life After Venovenous Extracorporeal Membrane Oxygenation

Long-Term Health-Related Quality of Life After Venovenous Extracorporeal Membrane Oxygenation

This study examined the long-term health-related quality of life in adult patients treated with venovenous extracorporeal membrane oxygenation (V-V ECMO) for severe acute respiratory failure in Ireland. A retrospective, cross-sectional... read more